干旱区生态环境知识资源中心(Arid): Metastatic cancer along ancient Silk Road: A possible case from Xinjiang (China)

Arid

DOI	10.1016/j.ijpp.2022.03.001
	Metastatic cancer along ancient Silk Road: A possible case from Xinjiang (China)
	He, Letian; Gibbon, Victoria E.; Xiao, Xiaoyong; Wang, Bo; Li, Haijun
通讯作者	He, LT
来源期刊	INTERNATIONAL JOURNAL OF PALEOPATHOLOGY
ISSN	1879-9817
EISSN	1879-9825
出版年	2022
卷号	37 页码:23-29
英文摘要	Objective: Palaeopathological evidence of cancer, especially metastatic cancer, is rare in China. This paper de-scribes and diagnoses a cranium with multiple lytic lesions recovered from the Sampula cemetery in Xinjiang, attempting to diagnose the type of disease that could have caused the pathological lesions observed. Material: A cranium from an adult male (#00106) was recovered from the Sampula cemetery (dated to 55 BCE to 335 CE) located in the Luopu County, the Hotan River oasis on the southern edge of the Tarim Basin in southern Xinjiang.Methods: The cranium was assessed macroscopically and radiographically (CT). Results: Multiple osteolytic lesions with irregular and moth-eaten margins were detected in cranium #00106. CT scans revealed the development of the lesions began at the diploe and identified a button sequestrum.Conclusions: Based on lesion characteristics, metastatic carcinoma was likely the cause of lesions found in cra-nium #00106. Significance: This case has expanded our knowledge of the malignant neoplasms of ancient populations in northwest China and discusses the possible risk factors in the occurrence of cancer in the Sampula site, as well as the possible impacts of skeletal metastases on the individual. Limitations: The distribution of osteolytic lesions over the complete skeleton cannot be observed because of the unavailability of postcranial bone.Suggestions for future research: With the increasing number of reports describing diseases in ancient China, the patterns of diseases occurrence and development can be further explored from spatial and temporal perspectives.
英文关键词	Multiple osteolytic lesions CT imaging Sampula cemetery Xinjiang
类型	Article
语种	英语
收录类别	SCI-E ; SSCI
WOS记录号	WOS:000783945700001
WOS关键词	LANGERHANS CELL HISTIOCYTOSIS ; MULTIPLE-MYELOMA ; CARCINOMA ; AGE ; PALEOPATHOLOGY ; CRYPTOCOCCOSIS ; INVOLVEMENT ; PATHOLOGY ; SKELETON ; LESIONS
WOS类目	Paleontology ; Pathology
WOS研究方向	Paleontology ; Pathology
资源类型	期刊论文
条目标识符	http://119.78.100.177/qdio/handle/2XILL650/393205
推荐引用方式 GB/T 7714	He, Letian,Gibbon, Victoria E.,Xiao, Xiaoyong,et al. Metastatic cancer along ancient Silk Road: A possible case from Xinjiang (China)[J],2022,37:23-29.
APA	He, Letian,Gibbon, Victoria E.,Xiao, Xiaoyong,Wang, Bo,&Li, Haijun.(2022).Metastatic cancer along ancient Silk Road: A possible case from Xinjiang (China).INTERNATIONAL JOURNAL OF PALEOPATHOLOGY,37,23-29.
MLA	He, Letian,et al."Metastatic cancer along ancient Silk Road: A possible case from Xinjiang (China)".INTERNATIONAL JOURNAL OF PALEOPATHOLOGY 37(2022):23-29.