干旱区生态环境知识资源中心(Arid): The Construction and Exploration of a Comprehensive MicroRNA Centered Regulatory Network in Foxtail Millet (Setaria italica L.)

Arid

DOI	10.3389/fpls.2022.848474
	The Construction and Exploration of a Comprehensive MicroRNA Centered Regulatory Network in Foxtail Millet (Setaria italica L.)
	Deng, Yang; Zhang, Haolin; Wang, Hailong; Xing, Guofang; Lei, Biao; Kuang, Zheng; Zhao, Yongxin; Li, Congcong; Dai, Shaojun; Yang, Xiaozeng; Wei, Jianhua; Zhang, Jiewei
通讯作者	Yang, XZ ; Wei, JH ; Zhang, JW
来源期刊	FRONTIERS IN PLANT SCIENCE
ISSN	1664-462X
出版年	2022
卷号	13
英文摘要	MicroRNA (miRNA) is an essential endogenous post-transcriptional regulatory factor, and foxtail millet (Setaria italica L.) is an ideal C4 model cereal that is a highly valuable crop in semiarid and arid areas. The Research on comprehensive and high confidence identification and annotation of foxtail millet miRNAs needs to be strengthened, and to our knowledge, there is no information on the regulatory network of foxtail millet miRNA. In this study, 136 high confidence miRNAs were identified through high-throughput sequencing of the small RNAs in seven tissues at the shooting and grain filling stages of foxtail millet. A total of 2,417 target genes were obtained by combining computational biology software and degradome sequencing methods. Furthermore, an analysis using transcriptome sequencing revealed the relationships between miRNAs and their target genes and simultaneously explored key regulatory modules in panicles during the grain filling stage. An miRNA regulatory network was constructed to explore the functions of miRNA in more detail. This network, centered on miRNAs and combining upstream transcriptional factors and downstream target genes, is primarily composed of feed forward loop motifs, which greatly enhances our knowledge of the potential functions of miRNAs and uncovers numerous previously unknown regulatory links. This study provides a solid foundation for research on the function and regulatory network of miRNAs in foxtail millet.
英文关键词	foxtail millet expression correlation regulatory network microRNA PARE-seq sRNA-seq
类型	Article
语种	英语
开放获取类型	gold, Green Published
收录类别	SCI-E
WOS记录号	WOS:000800044800001
WOS关键词	GENOME ; MIRNAS ; PREDICTION ; IDENTIFICATION ; ANNOTATION ; CRITERIA ; TARGETS ; GENES
WOS类目	Plant Sciences
WOS研究方向	Plant Sciences
资源类型	期刊论文
条目标识符	http://119.78.100.177/qdio/handle/2XILL650/392804
推荐引用方式 GB/T 7714	Deng, Yang,Zhang, Haolin,Wang, Hailong,et al. The Construction and Exploration of a Comprehensive MicroRNA Centered Regulatory Network in Foxtail Millet (Setaria italica L.)[J],2022,13.
APA	Deng, Yang.,Zhang, Haolin.,Wang, Hailong.,Xing, Guofang.,Lei, Biao.,...&Zhang, Jiewei.(2022).The Construction and Exploration of a Comprehensive MicroRNA Centered Regulatory Network in Foxtail Millet (Setaria italica L.).FRONTIERS IN PLANT SCIENCE,13.
MLA	Deng, Yang,et al."The Construction and Exploration of a Comprehensive MicroRNA Centered Regulatory Network in Foxtail Millet (Setaria italica L.)".FRONTIERS IN PLANT SCIENCE 13(2022).