Arid
DOI10.3389/fnins.2022.867664
A dominant set-informed interpretable fuzzy system for automated diagnosis of dementia
Chen, Tianhua; Su, Pan; Shen, Yinghua; Chen, Lu; Mahmud, Mufti; Zhao, Yitian; Antoniou, Grigoris
通讯作者Chen, TH
来源期刊FRONTIERS IN NEUROSCIENCE
EISSN1662-453X
出版年2022
卷号16
英文摘要Dementia is an incurable neurodegenerative disease primarily affecting the older population, for which the World Health Organisation has set to promoting early diagnosis and timely management as one of the primary goals for dementia care. While a range of popular machine learning algorithms and their variants have been applied for dementia diagnosis, fuzzy systems, which have been known effective in dealing with uncertainty and offer to explicitly reason how a diagnosis can be inferred, sporadically appear in recent literature. Given the advantages of a fuzzy rule-based model, which could potentially result in a clinical decision support system that offers understandable rules and a transparent inference process to support dementia diagnosis, this paper proposes a novel fuzzy inference system by adapting the concept of dominant sets that arise from the study of graph theory. A peeling-off strategy is used to iteratively extract from the constructed edge-weighted graph a collection of dominant sets. Each dominant set is further converted into a parameterized fuzzy rule, which is finally optimized in a supervised adaptive network-based fuzzy inference framework. An illustrative example is provided that demonstrates the interpretable rules and the transparent reasoning process of reaching a decision. Further systematic experiments conducted on data from the Open Access Series of Imaging Studies (OASIS) repository, also validate its superior performance over alternative methods.
英文关键词clinical decision support medical diagnostic systems dementia Alzheimer's disease fuzzy systems explainable AI
类型Article
语种英语
开放获取类型gold, Green Published, Green Accepted
收录类别SCI-E
WOS记录号WOS:000840822100001
WOS关键词GENETIC ALGORITHM ; CLASSIFICATION ; RELIABILITY ; RULES ; SLAVE
WOS类目Neurosciences
WOS研究方向Neurosciences & Neurology
资源类型期刊论文
条目标识符http://119.78.100.177/qdio/handle/2XILL650/392794
推荐引用方式
GB/T 7714
Chen, Tianhua,Su, Pan,Shen, Yinghua,et al. A dominant set-informed interpretable fuzzy system for automated diagnosis of dementia[J],2022,16.
APA Chen, Tianhua.,Su, Pan.,Shen, Yinghua.,Chen, Lu.,Mahmud, Mufti.,...&Antoniou, Grigoris.(2022).A dominant set-informed interpretable fuzzy system for automated diagnosis of dementia.FRONTIERS IN NEUROSCIENCE,16.
MLA Chen, Tianhua,et al."A dominant set-informed interpretable fuzzy system for automated diagnosis of dementia".FRONTIERS IN NEUROSCIENCE 16(2022).
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