干旱区生态环境知识资源中心(Arid): Accumulation, metabolites formation and elimination behavior of rac-glufosinate-ammonium and glufosinate-P in zebrafish (Danio rerio)

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DOI	10.1016/j.fochx.2022.100383
	Accumulation, metabolites formation and elimination behavior of rac-glufosinate-ammonium and glufosinate-P in zebrafish (Danio rerio)
	Wang, Fei; Lin, Qiao; Shi, Xueqin; Li, Yunfang; Deng, Pengyu; Zhang, Yuping; Hu, Deyu
通讯作者	Zhang, YP ; Hu, DY
来源期刊	FOOD CHEMISTRY-X
ISSN	2590-1575
出版年	2022
卷号	15
英文摘要	An efficient trace detection method for the determination of residues of the glufosinate enantiomers and metabolites in zebrafish by HPLC???Q-Exactive Orbitrap Mass Spectrometry was developed. After the purification of dichloromethane and Oasis PRiME HLB SPE column, the recovery ranges from 77% to 104%, with RSD < 10.03%. The limits of quantitation in zebrafish were 0.006???0.02 mg/kg. The results revealed zebrafish absorbed glufosinate slowly, reaching a steady state in 10???14 days, and the bioaccumulation factor (BCF) of D/Lglufosinate-ammonium was less than 0.3. L-glufosinate-ammonium accumulated preferentially in zebrafish. The residue of the metabolite N-acetyl glutamate (NAG) was smaller than that of 3-methyl phosphonic acid (MPP). D/L-glufosinate-ammonium had an elimination half-life of less than 2.3 days during the elimination phase. The bioaccumulation and elimination behavior of glufosinate-ammonium in zebrafish aquatic system was shown in this work, which offered scientific data for assessing the food safety of rac-glufosinate-ammonium and glufosinate-P (pure L-glufosinate-ammonium) in fish.
英文关键词	Rac-glufosinate-ammonium Glufosinate-P Degradation Bioaccumulation Metabolites Zebrafish
类型	Article
语种	英语
开放获取类型	Green Published
收录类别	SCI-E
WOS记录号	WOS:000829178800010
WOS关键词	TANDEM MASS-SPECTROMETRY ; LIQUID-CHROMATOGRAPHY ; GLYPHOSATE ; BIOACCUMULATION ; DERIVATIZATION ; RESIDUE ; RISK ; ACID
WOS类目	Chemistry, Applied ; Food Science & Technology
WOS研究方向	Chemistry ; Food Science & Technology
资源类型	期刊论文
条目标识符	http://119.78.100.177/qdio/handle/2XILL650/392596
推荐引用方式 GB/T 7714	Wang, Fei,Lin, Qiao,Shi, Xueqin,et al. Accumulation, metabolites formation and elimination behavior of rac-glufosinate-ammonium and glufosinate-P in zebrafish (Danio rerio)[J],2022,15.
APA	Wang, Fei.,Lin, Qiao.,Shi, Xueqin.,Li, Yunfang.,Deng, Pengyu.,...&Hu, Deyu.(2022).Accumulation, metabolites formation and elimination behavior of rac-glufosinate-ammonium and glufosinate-P in zebrafish (Danio rerio).FOOD CHEMISTRY-X,15.
MLA	Wang, Fei,et al."Accumulation, metabolites formation and elimination behavior of rac-glufosinate-ammonium and glufosinate-P in zebrafish (Danio rerio)".FOOD CHEMISTRY-X 15(2022).