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DOI | 10.1016/j.compbiomed.2022.105780 |
Nonfinite-modality data augmentation for brain image registration | |
He, Yuanbo; Wang, Aoyu; Li, Shuai; Yang, Yikang; Hao, Aimin | |
通讯作者 | Li, S |
来源期刊 | COMPUTERS IN BIOLOGY AND MEDICINE
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ISSN | 0010-4825 |
EISSN | 1879-0534 |
出版年 | 2022 |
卷号 | 147 |
英文摘要 | Brain image registration is fundamental for brain medical image analysis. However, the lack of paired images with diverse modalities and corresponding ground truth deformations for training hinder its development. We propose a novel nonfinite-modality data augmentation for brain image registration to combat this. Specifically, some available whole-brain segmentation masks, including complete fine brain anatomical structures, are collected from the actual brain dataset, OASIS-3. One whole-brain segmentation mask can generate many nonfinite-modality brain images by randomly merging some fine anatomical structures and subsequently sampling the intensities for each fine anatomical structure using random Gaussian distribution. Furthermore, to get more realistic deformations as the ground truth, an improved 3D Variational Auto-encoder (VAE) is proposed by introducing the intensity-level reconstruction loss and the structure-level reconstruction loss. Based on the generated images and trained improved 3D VAE, a new Synthetic Nonfinite-Modality Brain Image Dataset (SNMBID) is created. Experiments show that pre-training on SNMBID can improve the accuracy of registration. Notably, SNMBID can be a landmark for evaluating other brain registration methods, and the model trained on the SNMBID can be a baseline for the brain image registration task. Our code is available at https://github.com/MangoWAY/SMIBID_BrainRegistration. |
英文关键词 | Nonfinite-modality Data augmentation Improved 3D VAE Brain image registration |
类型 | Article |
语种 | 英语 |
收录类别 | SCI-E |
WOS记录号 | WOS:000833546500004 |
WOS关键词 | ALGORITHMS ; MRI |
WOS类目 | Biology ; Computer Science, Interdisciplinary Applications ; Engineering, Biomedical ; Mathematical & Computational Biology |
WOS研究方向 | Life Sciences & Biomedicine - Other Topics ; Computer Science ; Engineering ; Mathematical & Computational Biology |
资源类型 | 期刊论文 |
条目标识符 | http://119.78.100.177/qdio/handle/2XILL650/392189 |
推荐引用方式 GB/T 7714 | He, Yuanbo,Wang, Aoyu,Li, Shuai,et al. Nonfinite-modality data augmentation for brain image registration[J],2022,147. |
APA | He, Yuanbo,Wang, Aoyu,Li, Shuai,Yang, Yikang,&Hao, Aimin.(2022).Nonfinite-modality data augmentation for brain image registration.COMPUTERS IN BIOLOGY AND MEDICINE,147. |
MLA | He, Yuanbo,et al."Nonfinite-modality data augmentation for brain image registration".COMPUTERS IN BIOLOGY AND MEDICINE 147(2022). |
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