干旱区生态环境知识资源中心(Arid): Are herbal medicines alone or in combination for diabetic peripheral neuropathy more effective than methylcobalamin alone? A systematic review and meta-analysis

Arid

DOI	10.1016/j.ctcp.2022.101657
	Are herbal medicines alone or in combination for diabetic peripheral neuropathy more effective than methylcobalamin alone? A systematic review and meta-analysis
	Lee, Chang-Woo; Jin, Joon -Soo; Kwon, Seungwon; Jin, Chul; Cho, Seung-Yeon; Park, Seong-Uk; Jung, Woo-Sang; Moon, Sang-Kwan; Park, Jung-Mi; Ko, Chang -Nam; Cho, Ki-Ho
通讯作者	Kwon, S ; Park, JM
来源期刊	COMPLEMENTARY THERAPIES IN CLINICAL PRACTICE
ISSN	1744-3881
EISSN	1873-6947
出版年	2022
卷号	49
英文摘要	Background and purpose: In Asian countries, herbal medicines have been used to treat diabetic peripheral neuropathy (DPN) as an adjunctive therapy. This review aims to assess the effectiveness and safety of herbal medicines for the treatment of DPN.Methods: A literature search was conducted on PubMed, Embase, CENTRAL, Scopus, CINAHL, CNKI, DBPIA, and OASIS for randomized controlled trials that evaluated the effects of herbal medicines on DPN. The oral methylcobalamin administered group was selected as the control. The primary outcome measure was nerve conduction velocity (NCV), and the secondary outcome measure was the total efficacy rate (TER). The methodological quality of the included studies was assessed using the Cochrane risk of bias tool. A meta-analysis was conducted using Review Manager 5.4.1 software. Results: Seventy-two RCTs with a total of 6260 patients were included. The meta-analysis showed that herbal medicine and co-administration of herbal medicine and methylcobalamin (CHM) treatment for DPN significantly increased the sensory nerve conduction velocity (SNCV) and motor nerve conduction velocity (MNCV) of the median and common peroneal nerves than methylcobalamin treatment alone. Herbal medicine and CHM treatment for DPN also significantly improved the TER compared to the control group. Herbal medicine and CHM treatment was found to be relatively safe.Conclusion: Our study suggests that herbal medicine and CHM might be more effective than methylcobalamin alone in the management of DPN. Further rigorous studies should be conducted to make more definite conclusions.
英文关键词	Diabetic peripheral neuropathy Herbal medicine Meta -analysis Nerve conduction velocity Systematic review
类型	Review
语种	英语
收录类别	SCI-E
WOS记录号	WOS:000848012600002
WOS关键词	DANGGUI SINI DECOCTION ; NERVE-CONDUCTION ; INJURY ; TANG
WOS类目	Integrative & Complementary Medicine
WOS研究方向	Integrative & Complementary Medicine
资源类型	期刊论文
条目标识符	http://119.78.100.177/qdio/handle/2XILL650/392175
推荐引用方式 GB/T 7714	Lee, Chang-Woo,Jin, Joon -Soo,Kwon, Seungwon,et al. Are herbal medicines alone or in combination for diabetic peripheral neuropathy more effective than methylcobalamin alone? A systematic review and meta-analysis[J],2022,49.
APA	Lee, Chang-Woo.,Jin, Joon -Soo.,Kwon, Seungwon.,Jin, Chul.,Cho, Seung-Yeon.,...&Cho, Ki-Ho.(2022).Are herbal medicines alone or in combination for diabetic peripheral neuropathy more effective than methylcobalamin alone? A systematic review and meta-analysis.COMPLEMENTARY THERAPIES IN CLINICAL PRACTICE,49.
MLA	Lee, Chang-Woo,et al."Are herbal medicines alone or in combination for diabetic peripheral neuropathy more effective than methylcobalamin alone? A systematic review and meta-analysis".COMPLEMENTARY THERAPIES IN CLINICAL PRACTICE 49(2022).