干旱区生态环境知识资源中心(Arid): A chromosomal-level reference genome of the widely utilized Coccidioides posadasii laboratory strain Silveira

Arid

DOI	10.1093/g3journal/jkac031
	A chromosomal-level reference genome of the widely utilized Coccidioides posadasii laboratory strain Silveira
	Teixeira, Marcus de Melo; Stajich, Jason E.; Sahl, Jason W.; Thompson, George R. I. I. I. I. I. I.; Brem, Rachel B.; Dubin, Claire A.; Blackmon, Austin, V; Mead, Heather L.; Keim, Paul; Barker, Bridget M.
通讯作者	Barker, BM (corresponding author)，No Arizona Univ, Pathogen & Microbiome Inst, Appl Res & Dev Bldg,1395 5 Knoles Dr,Ste 204, Flagstaff, AZ 86011 USA.
来源期刊	G3-GENES GENOMES GENETICS
ISSN	2160-1836
出版年	2022-02
英文摘要	Coccidioidomycosis is a common fungal disease that is endemic to arid and semi-arid regions of both American continents. Coccidioides immitis and Coccidioides posadasii are the etiological agents of the disease, also known as Valley Fever. For several decades, the C. posadasii strain Silveira has been used widely in vaccine studies, is the source strain for production of diagnostic antigens, and is a widely used experimental strain for functional studies. In 2009, the genome was sequenced using Sanger sequencing technology, and a draft assembly and annotation were made available. In this study, the genome of the Silveira strain was sequenced using single molecule real-time sequencing PacBio technology, assembled into chromosomal-level contigs, genotyped, and the genome was reannotated using sophisticated and curated in silico tools. This high-quality genome sequencing effort has improved our understanding of chromosomal structure, gene set annotation, and lays the groundwork for identification of structural variants (e.g. transversions, translocations, and copy number variants), assessment of gene gain and loss, and comparison of transposable elements in future phylogenetic and population genomics studies.
英文关键词	valley fever long-read sequencing funannotate human fungal pathogen fungal genomes reference genome coccidioidomycosis
类型	Article ; Early Access
语种	英语
开放获取类型	Green Submitted, gold
收录类别	SCI-E
WOS记录号	WOS:000758836000001
WOS关键词	POPULATION-STRUCTURE ; IMMITIS ; MICE ; ACCURATE ; EXPRESSION ; ALGORITHM ; VACCINE ; IMMUNIZATION ; ANNOTATION ; GENERATION
WOS类目	Genetics & Heredity
WOS研究方向	Genetics & Heredity
资源类型	期刊论文
条目标识符	http://119.78.100.177/qdio/handle/2XILL650/377327
作者单位	[Teixeira, Marcus de Melo] Univ Brasilia, Fac Med, BR-70910900 Brasilia, DF, Brazil; [Teixeira, Marcus de Melo; Sahl, Jason W.; Blackmon, Austin, V; Mead, Heather L.; Keim, Paul; Barker, Bridget M.] No Arizona Univ, Pathogen & Microbiome Inst, Appl Res & Dev Bldg,1395 5 Knoles Dr,Ste 204, Flagstaff, AZ 86011 USA; [Stajich, Jason E.] Univ Calif Riverside, Inst Integrat Genome Biol, Riverside, CA 92521 USA; [Stajich, Jason E.] Univ Calif Riverside, Dept Microbiol & Plant Pathol, Riverside, CA 92521 USA; [Thompson, George R. I. I. I. I. I. I.] Univ Calif Davis, Dept Med Microbiol & Immunol, Davis, CA 95616 USA; [Brem, Rachel B.; Dubin, Claire A.] Univ Calif Berkeley, Dept Plant & Microbial Biol, Berkeley, CA 94720 USA
推荐引用方式 GB/T 7714	Teixeira, Marcus de Melo,Stajich, Jason E.,Sahl, Jason W.,et al. A chromosomal-level reference genome of the widely utilized Coccidioides posadasii laboratory strain Silveira[J],2022.
APA	Teixeira, Marcus de Melo.,Stajich, Jason E..,Sahl, Jason W..,Thompson, George R. I. I. I. I. I. I..,Brem, Rachel B..,...&Barker, Bridget M..(2022).A chromosomal-level reference genome of the widely utilized Coccidioides posadasii laboratory strain Silveira.G3-GENES GENOMES GENETICS.
MLA	Teixeira, Marcus de Melo,et al."A chromosomal-level reference genome of the widely utilized Coccidioides posadasii laboratory strain Silveira".G3-GENES GENOMES GENETICS (2022).