干旱区生态环境知识资源中心(Arid): Identification of Sterols from Anabasis articulata (Forssk.) Moq. (Chenopodiaceae) Growing in Algeria and Study of Their Potential Bioactivity

Arid

DOI	10.1007/s12649-022-01717-w
	Identification of Sterols from Anabasis articulata (Forssk.) Moq. (Chenopodiaceae) Growing in Algeria and Study of Their Potential Bioactivity
	Ben Menni, Dounia; Belyagoubi-Benhammou, Nabila; Benmahieddine, Assia; Ben Menni, Hanane; Gismondi, Angelo; Monteleone, Valentina; Di Marco, Gabriele; D'Agostino, Alessia; Canini, Antonela; Benamar, Houari; Atik-Bekkara, Fawzia
通讯作者	Belyagoubi-Benhammou, N (corresponding author)，Univ Abou Bekr Belkaid Tlemcen, Earth & Universe, Fac Nat & Life Sci, Nat Prod Lab,Dept Biol, Tilimsen 13000, Algeria.
来源期刊	WASTE AND BIOMASS VALORIZATION
ISSN	1877-2641
EISSN	1877-265X
出版年	2022-02
英文摘要	Purpose Anabasis articulata (Forssk.) Moq. (Chenopodiaceae), also called Eshnan, Ajremor Berry bearing glasswort, is widely distributed in Syrian, Algerian, Jordan, Lebanon, Saudi Arabia, Egyptian and Iraqi desert, Spain (Alicante, Almeria, Granada and Murcia provinces), Mauritania, Western Sahara and Morocco. Anabasis articulata is broadly used in folk medicine to treat diabetes, fever, eczema and kidney infections. The objective of this work was to examine the potential bioactivity of the plant, in vitro and in vivo experiment. Methods The sterol-rich extract was identified by GC/MS analysis. The antioxidant potential, anti-tyrosinase and antiproliferative activities, was evaluated by in vitro assays and anti-inflammatory function was determined by in vivo assay. Results The results revealed that the chromatographic analysis showed the presence of four sterols in the plant samples. A preliminary evaluation of the antiproliferative effect of A. articulata against two human tumor cell lines, MCF7 and MDA-MB 231, was evaluated by MTT assay. The plant extract was also subjected to four different in vitro antioxidant assays (i.e. total antioxidant capacity, reducing power, DPPH and beta-carotene-linoleic acid bleaching). The sterol-rich extract also showed a high anti-tyrosinase activity, and an acetylcholinesterase inhibitory effect, and in vivo toxicological and anti-inflammatory function of A. articulata sterols was tested on rats with carrageenan-induced inflammatory paw edema. Conclusions All this evidence suggests the possible application of the aerial part of A. articulata as food additive, in pharmaceutical and cosmetic industries. [GRAPHICS]
英文关键词	Anabasis articulata (Forssk.) Moq (Chenopodiaceae) Antiproliferative Antioxidant Anti-tyrosinase Anti-acetylcholinesterase Anti-inflammatory
类型	Article ; Early Access
语种	英语
收录类别	SCI-E
WOS记录号	WOS:000759319000002
WOS关键词	BREAST-CANCER CELLS ; BETA-SITOSTEROL ; ACETYLCHOLINESTERASE INHIBITORS ; LIPID-PEROXIDATION ; ANTIOXIDANT ; APOPTOSIS ; CHROMATOGRAPHY ; STIGMASTEROL ; PHYTOSTEROL ; GLUCOSIDE
WOS类目	Environmental Sciences
WOS研究方向	Environmental Sciences & Ecology
资源类型	期刊论文
条目标识符	http://119.78.100.177/qdio/handle/2XILL650/377239
作者单位	[Ben Menni, Dounia; Belyagoubi-Benhammou, Nabila; Benmahieddine, Assia; Ben Menni, Hanane; Atik-Bekkara, Fawzia] Univ Abou Bekr Belkaid Tlemcen, Earth & Universe, Fac Nat & Life Sci, Nat Prod Lab,Dept Biol, Tilimsen 13000, Algeria; [Gismondi, Angelo; Monteleone, Valentina; Di Marco, Gabriele; D'Agostino, Alessia; Canini, Antonela] Univ Roma Tor Vergata, Dept Biol, Via Ric Sci 1, I-00133 Rome, Italy; [Benamar, Houari] Univ Mostaganem Abdelhamid Ibn Badis, Fac Nat Sci & Life, Dept Biol, POB 188, Mostaganem 27000, Algeria; [Benamar, Houari] Univ Oran1, Fac Nat Sci & Life, Dept Biol, POB 1524, Oran 31000, Algeria
推荐引用方式 GB/T 7714	Ben Menni, Dounia,Belyagoubi-Benhammou, Nabila,Benmahieddine, Assia,et al. Identification of Sterols from Anabasis articulata (Forssk.) Moq. (Chenopodiaceae) Growing in Algeria and Study of Their Potential Bioactivity[J],2022.
APA	Ben Menni, Dounia.,Belyagoubi-Benhammou, Nabila.,Benmahieddine, Assia.,Ben Menni, Hanane.,Gismondi, Angelo.,...&Atik-Bekkara, Fawzia.(2022).Identification of Sterols from Anabasis articulata (Forssk.) Moq. (Chenopodiaceae) Growing in Algeria and Study of Their Potential Bioactivity.WASTE AND BIOMASS VALORIZATION.
MLA	Ben Menni, Dounia,et al."Identification of Sterols from Anabasis articulata (Forssk.) Moq. (Chenopodiaceae) Growing in Algeria and Study of Their Potential Bioactivity".WASTE AND BIOMASS VALORIZATION (2022).