干旱区生态环境知识资源中心(Arid): Observational study to estimate the proportion of surgical site infection following excision of ulcerated skin tumours (OASIS study)

Arid

DOI	10.1111/ced.15037
	Observational study to estimate the proportion of surgical site infection following excision of ulcerated skin tumours (OASIS study)
	Abbott, R. A.; Cordaro, A.; Lloyd, B.; Cannings-John, R.; Wootton, M.; Kirby, N.; Pickles, T.; McQueen, A.; Westmoreland, M.; Ziaj, S.; Martin-Clavijo, A.; Wernham, A.; Matin, R.; Thomas-Jones, E.
通讯作者	Abbott, RA (corresponding author)，Univ Hosp Wales, Dept Dermatol, Heath Pk, Cardiff CF14 4XW, Wales.
来源期刊	CLINICAL AND EXPERIMENTAL DERMATOLOGY
ISSN	0307-6938
EISSN	1365-2230
出版年	2021-12
英文摘要	Background Ulceration is a recognized risk factor for surgical site infection (SSI); however, the proportion of patients developing SSI after excision of an ulcerated skin cancer is unknown. Aim To determine the proportion of participants with SSI after surgical excision of an ulcerated skin cancer. A secondary aim was to assess feasibility outcomes to inform the design of a randomized controlled trial to investigate the benefits and harms of perioperative antibiotics following excision of ulcerated tumours. Methods This was a multicentre, prospective, observational study of patients undergoing excision of an ulcerated skin cancer between March 2019 and March 2020. Prior to surgical excision, surface swabs of the ulcerated tumours of participants recruited from one centre were undertaken to determine organism growth. At 4 weeks after surgery, all participants were e-mailed or posted the Wound Healing Questionnaire (WHQ) to determine whether they had developed SSI. Results In total, 148 participants were recruited 105 (70.9%) males; mean +/- SD age 77.1 +/- 12.3 years. Primary outcome data were available for 116 (78.4%) participants, of whom 35 (30.2%) were identified as having an SSI using the WHQ with a cutoff score of 8, and 47 (40.5%) were identified with a cutoff score of 6. Using the modified WHQ in participants with wounds left to heal by secondary intention, 33 (28.4%) and 43 (37.1%) were identified to have SSI respectively. Conclusion This prospective evaluation of SSI identified with the WHQ following excision of ulcerated skin cancers demonstrated a high proportion with SSI. The WHQ was acceptable to patients; however, further evaluation is required to ensure validity in assessing skin wounds.
类型	Article ; Early Access
语种	英语
收录类别	SCI-E
WOS记录号	WOS:000736441000001
WOS关键词	WOUND INFECTIONS ; RISK-FACTORS
WOS类目	Dermatology
WOS研究方向	Dermatology
资源类型	期刊论文
条目标识符	http://119.78.100.177/qdio/handle/2XILL650/377037
作者单位	[Abbott, R. A.; Cordaro, A.; McQueen, A.] Univ Hosp Wales, Cardiff & Vale Univ Hlth Board, Dept Dermatol, Cardiff, Wales; [Lloyd, B.; Cannings-John, R.; Kirby, N.; Pickles, T.; Thomas-Jones, E.] Cardiff Univ, Ctr Trials Res, Cardiff, Wales; [Wootton, M.] Publ Hlth Wales, Specialist Antimicrobial Chemotherapy Unit, Cardiff, Wales; [Westmoreland, M.; Ziaj, S.; Matin, R.] Oxford Univ Hosp NHS Fdn Trust, Churchill Hosp, Dept Dermatol, Oxford, England; [Martin-Clavijo, A.] Univ Hosp Birmingham NHS Fdn Trust, Queen Elizabeth Hosp, Dept Dermatol, Birmingham, W Midlands, England; [Wernham, A.] Walsall Healthcare NHS Trust, Dept Dermatol, Manor Hosp, Wallsall, England; [Wernham, A.] Leicester Univ Hosp NHS Trust, Leicester Royal Infirm, Dept Dermatol, Leicester, Leics, England
推荐引用方式 GB/T 7714	Abbott, R. A.,Cordaro, A.,Lloyd, B.,et al. Observational study to estimate the proportion of surgical site infection following excision of ulcerated skin tumours (OASIS study)[J],2021.
APA	Abbott, R. A..,Cordaro, A..,Lloyd, B..,Cannings-John, R..,Wootton, M..,...&Thomas-Jones, E..(2021).Observational study to estimate the proportion of surgical site infection following excision of ulcerated skin tumours (OASIS study).CLINICAL AND EXPERIMENTAL DERMATOLOGY.
MLA	Abbott, R. A.,et al."Observational study to estimate the proportion of surgical site infection following excision of ulcerated skin tumours (OASIS study)".CLINICAL AND EXPERIMENTAL DERMATOLOGY (2021).