干旱区生态环境知识资源中心(Arid): Doping-control analysis of 14 diuretics in animal-derived foods using ultra-high-performance liquid chromatography-tandem mass spectrometry

Arid

DOI	10.1016/j.microc.2021.106948
	Doping-control analysis of 14 diuretics in animal-derived foods using ultra-high-performance liquid chromatography-tandem mass spectrometry
	Yan, Yonghuan; Lian, Kaoqi; Zhang, Haichao; An, Jing; Zhang, Yan; Kang, Weijun; Ai, Lianfeng
通讯作者	Zhang, Y (corresponding author)，Hebei Med Univ, Coll Forens Med, Hebei Key Lab Forens Med, Shijiazhuang 050017, Hebei, Peoples R China. ; Kang, WJ (corresponding author)，Hebei Med Univ, Sch Publ Hlth, Dept Sanit Inspect, Shijiazhuang 050017, Hebei, Peoples R China. ; Zhang, Y (corresponding author)，Hebei Food Inspect & Res Inst, Hebei Food Safety Key Lab, Shijiazhuang 050227, Hebei, Peoples R China. ; Ai, LF (corresponding author)，Hebei Inst Drug & Med Device Control, Shijiazhuang 050299, Hebei, Peoples R China.
来源期刊	MICROCHEMICAL JOURNAL
ISSN	0026-265X
EISSN	1095-9149
出版年	2022
卷号	174
英文摘要	A rapid, sensitive, and confirmatory method was developed and validated for the determination of 14 diuretics in multiple animal-derived foods using ultra-high-performance liquid chromatography-tandem mass spectrometry (UHPLC-MS/MS). Analytes were extracted from samples using acetonitrile containing 0.1% formic acid (FA) and then purified and concentrated using an Oasis PRIME HLB cartridge. The extraction and purification as well as the chromatographic and MS conditions were investigated to increase sample throughput and sensitivity. Quantification was performed using MS/MS with an electrospray ionization source in the positive multiple reaction monitoring (MRM) mode. The overall recoveries ranged from 60.8 to 116.4% with intra-day and inter-day relative standard deviation lower than 11.8% and 12.2%, respectively. The limits of quantitation for different matrices (pork, beef, lamb, milk, and eggs) were between 0.53 and 2.43 mu g/kg, which were satisfactory for surveillance monitoring. The proposed method can be used to provide additional information for the reliable risk assessment of foodborne doping.
英文关键词	Diuretics Foodborne doping Animal-derived foods Ultra-high-performance liquid chromatography Mass spectrometry
类型	Article
语种	英语
收录类别	SCI-E
WOS记录号	WOS:000736677700011
WOS关键词	SOLID-PHASE EXTRACTION ; AGENTS ; URINE
WOS类目	Chemistry, Analytical
WOS研究方向	Chemistry
资源类型	期刊论文
条目标识符	http://119.78.100.177/qdio/handle/2XILL650/376924
作者单位	[Yan, Yonghuan; Zhang, Yan] Hebei Med Univ, Coll Forens Med, Hebei Key Lab Forens Med, Shijiazhuang 050017, Hebei, Peoples R China; [Lian, Kaoqi; An, Jing; Kang, Weijun] Hebei Med Univ, Sch Publ Hlth, Dept Sanit Inspect, Shijiazhuang 050017, Hebei, Peoples R China; [Zhang, Haichao; Ai, Lianfeng] Hebei Entry Exit Inspect & Quarantine Bur, Shijiazhuang 050051, Hebei, Peoples R China; [Zhang, Yan] Hebei Food Inspect & Res Inst, Hebei Food Safety Key Lab, Shijiazhuang 050227, Hebei, Peoples R China
推荐引用方式 GB/T 7714	Yan, Yonghuan,Lian, Kaoqi,Zhang, Haichao,et al. Doping-control analysis of 14 diuretics in animal-derived foods using ultra-high-performance liquid chromatography-tandem mass spectrometry[J],2022,174.
APA	Yan, Yonghuan.,Lian, Kaoqi.,Zhang, Haichao.,An, Jing.,Zhang, Yan.,...&Ai, Lianfeng.(2022).Doping-control analysis of 14 diuretics in animal-derived foods using ultra-high-performance liquid chromatography-tandem mass spectrometry.MICROCHEMICAL JOURNAL,174.
MLA	Yan, Yonghuan,et al."Doping-control analysis of 14 diuretics in animal-derived foods using ultra-high-performance liquid chromatography-tandem mass spectrometry".MICROCHEMICAL JOURNAL 174(2022).