干旱区生态环境知识资源中心(Arid): Anti-anger Effects of Herbal Medicine: A Mini-Review of Rat Studies

Arid

DOI	10.1007/s11655-022-3506-3
	Anti-anger Effects of Herbal Medicine: A Mini-Review of Rat Studies
	Kwon, Chan-Young; Suh, Hyo-Weon; Kim, Jong Woo; Chung, Sun-Yong
通讯作者	Chung, SY (corresponding author)，Kyung Hee Univ, Dept Neuropsychiat, Korean Med Hosp Gangdong, 892 Dongnam Ro, Seoul 05278, South Korea.
来源期刊	CHINESE JOURNAL OF INTEGRATIVE MEDICINE
ISSN	1672-0415
EISSN	1993-0402
出版年	2022
卷号	28 期号:3 页码:263-271
英文摘要	Objective To analyze the available data on the anti-anger effects of herbal medicines (HMs) as well as their underlying mechanisms in rat models. Methods From 6 electronic databases [PubMed, EMBASE, China National Knowledge Infrastructure (CNKI), Wanfang, Oriental Medicine Advanced Searching Integrated System (OASIS), and Research Information Sharing Service (RISS)], relevant animal experiments were searched by using anger, rats, and animal as search keywords. The last search was conducted on November 22, 2019, and all experiments involving rat models of anger and treatment using HMs published until the date of the search were considered. Results A total of 24 studies with 16 kinds of HMs were included. Most studies have used the tail irritating method and social isolation and resident intruder method to establish anger models. According to the included studies, the therapeutic mechanisms of HMs for anger regulation and important herbs by their frequency and/or preclinical evidence mainly incladed regulation of hemorheology (Bupleuri Radix, Paeoniae Radix Alba, and Glycyrrhizae Radix), regulation of sex hormones (Bupleuri Radix, Cyperi Rhizoma, and Paeoniae Radix Alba), regulation of neurotransmitters (Cyperi Rhizoma), regulation of anger-related genes (Bupleuri Radix, Glycyrrhizae Radix, and Paeoniae Radix Alba), and other effects. Overall, Liver (Gan) qi-smoothing herbs including Bupleuri Radix and Cyperi Rhizoma were the most frequently used. Conclusions This review found the frequent methods to establish an anger model, and major mechanisms of anti-anger effects of HMs. Interestingly, some Liver qi-smoothing herbs have been frequently used to investigate the anti-anger effects of HM. These findings provide insight into the role and relevance of HMs in the field of anger management.
英文关键词	anger anger management therapy herbal medicine Korean traditional medicine
类型	Article
语种	英语
收录类别	SCI-E
WOS记录号	WOS:000749008800002
WOS关键词	GENE-EXPRESSION PROFILE ; AGGRESSIVE-BEHAVIOR ; JINGQIANPING GRANULE ; STRESS ; BRAIN ; RISK ; TESTOSTERONE ; VIOLENCE ; HEALTH ; HEART
WOS类目	Integrative & Complementary Medicine
WOS研究方向	Integrative & Complementary Medicine
资源类型	期刊论文
条目标识符	http://119.78.100.177/qdio/handle/2XILL650/376508
作者单位	[Kwon, Chan-Young] Dong Eui Univ, Dept Oriental Neuropsychiat, Coll Korean Med, Busan 47227, South Korea; [Suh, Hyo-Weon; Kim, Jong Woo; Chung, Sun-Yong] Kyung Hee Univ, Dept Neuropsychiat, Korean Med Hosp Gangdong, 892 Dongnam Ro, Seoul 05278, South Korea
推荐引用方式 GB/T 7714	Kwon, Chan-Young,Suh, Hyo-Weon,Kim, Jong Woo,et al. Anti-anger Effects of Herbal Medicine: A Mini-Review of Rat Studies[J],2022,28(3):263-271.
APA	Kwon, Chan-Young,Suh, Hyo-Weon,Kim, Jong Woo,&Chung, Sun-Yong.(2022).Anti-anger Effects of Herbal Medicine: A Mini-Review of Rat Studies.CHINESE JOURNAL OF INTEGRATIVE MEDICINE,28(3),263-271.
MLA	Kwon, Chan-Young,et al."Anti-anger Effects of Herbal Medicine: A Mini-Review of Rat Studies".CHINESE JOURNAL OF INTEGRATIVE MEDICINE 28.3(2022):263-271.