干旱区生态环境知识资源中心(Arid): Comprehensive traditional East Asian medicine treatment strategy for obesity considering the therapeutic effects and adverse events A protocol for systematic review and network meta-analysis

Arid

DOI	10.1097/MD.0000000000028673
	Comprehensive traditional East Asian medicine treatment strategy for obesity considering the therapeutic effects and adverse events A protocol for systematic review and network meta-analysis
	Chu, Hongmin; Kang, Byungsoo; Youn, Bo-Young; Kim, Kwan-il; Park, Jinbong; Leem, Jungtae
通讯作者	Leem, J (corresponding author)，Wonkwang Univ, Res Ctr Tradit Korean Med, 460 Iksan Daero, Iksan, Jeollabuk Do, South Korea.
来源期刊	MEDICINE
ISSN	0025-7974
EISSN	1536-5964
出版年	2022
卷号	101 期号:6
英文摘要	Background: Obesity has become a serious global health problem due to its increasing prevalence. Because of several limitations or adverse events associated with conventional western medicine therapies, there has been an increase in demand for alternative therapies such as traditional East Asian medicine (TEAM). This study aims to provide comprehensive evidence-based information assessing the clinical efficacy and safety of TEAM treatment for obesity as the basis for reliable clinical strategies for patients with obesity. Methods: Electronic searches of the PubMed, Cochrane Library, EMBASE, China National Knowledge Infrastructure, OASIS, and Korea Citation Index will be performed. Methodological quality will be assessed using the risk of bias tool. The primary outcome for efficacy will be weight loss. The secondary outcomes will be response rate, body mass index, waist circumference, and blood pressure. We will also evaluate the rates of adverse events and mortality for safety assessment. First, we will conduct a conventional pairwise meta-analysis. Next, we will conduct network meta-analysis using the frequentist approach. We shall verify the assumption of network meta-analysis and provide network geometry, P-score, net league table, and intervention-based forest plot. A subgroup analysis will be conducted to ascertain the factors that affect treatment, such as dosage, treatment duration, and severity of obesity. Results: The results of this study will provide high-quality systematic reviews that can assist decision making in obesity management. Our network meta-analysis results can provide direct and indirect comparison evidence on comparative efficacy and safety. Conclusion: This study will provide fundamental data for prospective research on the application of TEAM in patients with obesity. Protocol registry number of online registry: This study protocol was registered in open Science framework (OSF) (Registration DOI: 10.17605/OSF.IO/ETWDS) .
英文关键词	acupuncture herbal medicine network meta-analysis obesity systematic review traditional East Asian medicine
类型	Review
语种	英语
开放获取类型	Green Published, gold
收录类别	SCI-E
WOS记录号	WOS:000753996800009
WOS关键词	INTERVENTIONS ; ACUPUNCTURE ; SIBUTRAMINE ; MANAGEMENT ; DIET
WOS类目	Medicine, General & Internal
WOS研究方向	General & Internal Medicine
资源类型	期刊论文
条目标识符	http://119.78.100.177/qdio/handle/2XILL650/376300
作者单位	[Chu, Hongmin] Daecheong Publ Hlth Subctr, 3 Daecheong Ro, Incheon, South Korea; [Kang, Byungsoo] Dongshin Univ, Coll Korean Med, 67 Dongsindae Gil, Naju Si, Jeollanamdo, South Korea; [Youn, Bo-Young] Kyung Hee Univ, Coll Korean Med, Dept Prevent Med, 26 Kyungheedae Ro, Seoul, South Korea; [Kim, Kwan-il] Kyung Hee Univ, Coll Korean Med, Dept Internal Med, Div Allergy,Immune Div Allergy Immune & Resp Syst, 23 Kyungheedae Ro, Seoul, South Korea; [Park, Jinbong] Kyung Hee Univ, Coll Korean Med, Dept Pharmacol, 26 Kyungheedae Ro, Seoul, South Korea; [Leem, Jungtae] Wonkwang Univ, Res Ctr Tradit Korean Med, 460 Iksan Daero, Iksan, Jeollabuk Do, South Korea
推荐引用方式 GB/T 7714	Chu, Hongmin,Kang, Byungsoo,Youn, Bo-Young,et al. Comprehensive traditional East Asian medicine treatment strategy for obesity considering the therapeutic effects and adverse events A protocol for systematic review and network meta-analysis[J],2022,101(6).
APA	Chu, Hongmin,Kang, Byungsoo,Youn, Bo-Young,Kim, Kwan-il,Park, Jinbong,&Leem, Jungtae.(2022).Comprehensive traditional East Asian medicine treatment strategy for obesity considering the therapeutic effects and adverse events A protocol for systematic review and network meta-analysis.MEDICINE,101(6).
MLA	Chu, Hongmin,et al."Comprehensive traditional East Asian medicine treatment strategy for obesity considering the therapeutic effects and adverse events A protocol for systematic review and network meta-analysis".MEDICINE 101.6(2022).