干旱区生态环境知识资源中心(Arid): Emergence of dengue virus serotype 2 in Mauritania and molecular characterization of its circulation in West Africa

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DOI	10.1371/journal.pntd.0009829
	Emergence of dengue virus serotype 2 in Mauritania and molecular characterization of its circulation in West Africa
	Fourie, Toscane; El Bara, Ahmed; Dubot-Peres, Audrey; Grard, Gilda; Briolant, Sebastien; Basco, Leonardo K.; Moukah, Mohamed Ouldabdallahi; Leparc-Goffart, Isabelle
通讯作者	Leparc-Goffart, I (corresponding author)，Aix Marseille Univ IRD 190 INSERM 1207, Unite Virus Emergents UVE, Marseille, France. ; Leparc-Goffart, I (corresponding author)，Inst Rech Biomed Armees, Marseille, France.
来源期刊	PLOS NEGLECTED TROPICAL DISEASES
ISSN	1935-2735
出版年	2021
卷号	15 期号:10
英文摘要	The number of sporadic and epidemic dengue fever cases have reportedly been increasing in recent years in some West African countries, such as Senegal and Mali. The first epidemic of laboratory-confirmed dengue occurred in Nouakchott, the capital city of Mauritania situated in the Saharan desert, in 2014. On-site diagnosis of dengue fever was established using a rapid diagnostic test for dengue. In parallel, the presence of Aedes aegypti mosquitoes in the city was confirmed. The initial diagnosis was confirmed by RT-PCR, which showed that all samples from the 2014 dengue epidemic in Nouakchott were dengue virus serotype 2 (DENV-2). The whole genome or envelope protein gene of these strains, together with other DENV-2 strains obtained from travelers returning from West African countries to France between 2016 and 2019 (including two Mauritanian strains in 2017 and 2018), were sequenced. Phylogenetic analysis suggested a recent emergence of an epidemic strain from the cosmopolitan genotype belonging to West African cosmopolitan lineage II, which is genetically distinct from African sylvatic genotype. The origin of this DENV-2 lineage is still unknown, but our data seem to suggest a recent and rapid dispersion of the epidemic strain throughout the region. More complete genome sequences of West African DENV-2 are required for a better understanding of the dynamics of its circulation. Arboviral surveillance and outbreak forecasting are urgently needed in West Africa.
类型	Article
语种	英语
开放获取类型	gold, Green Published
收录类别	SCI-E
WOS记录号	WOS:000750642600004
WOS关键词	AEGYPTI DIPTERA-CULICIDAE ; AEDES-AEGYPTI ; YELLOW-FEVER ; FEBRILE PATIENTS ; INFECTION ; SENEGAL ; SEROPREVALENCE ; SUSCEPTIBILITY ; ALBOPICTUS ; EPIDEMIC
WOS类目	Infectious Diseases ; Parasitology ; Tropical Medicine
WOS研究方向	Infectious Diseases ; Parasitology ; Tropical Medicine
资源类型	期刊论文
条目标识符	http://119.78.100.177/qdio/handle/2XILL650/375900
作者单位	[Fourie, Toscane; Dubot-Peres, Audrey; Grard, Gilda; Leparc-Goffart, Isabelle] Aix Marseille Univ IRD 190 INSERM 1207, Unite Virus Emergents UVE, Marseille, France; [Fourie, Toscane; Grard, Gilda; Briolant, Sebastien; Leparc-Goffart, Isabelle] Inst Rech Biomed Armees, Marseille, France; [El Bara, Ahmed] Inst Natl Rech Sante Publ, Nouakchott, Mauritania; [Briolant, Sebastien; Basco, Leonardo K.] Aix Marseille Univ, IRD, AP HM, SSA,VITROME, Marseille, France; [Briolant, Sebastien; Basco, Leonardo K.] IHU Mediterranee Infect, Marseille, France; [Moukah, Mohamed Ouldabdallahi] Univ Nouakchott Al Aasriya, Unite Rech Genomes & Milieux, Fac Sci & Tech, Nouakchott, Mauritania; [Moukah, Mohamed Ouldabdallahi] Initiat Mauritanienne Lutte Malad Endem MEDCINGO, Nouakchott, Mauritania
推荐引用方式 GB/T 7714	Fourie, Toscane,El Bara, Ahmed,Dubot-Peres, Audrey,et al. Emergence of dengue virus serotype 2 in Mauritania and molecular characterization of its circulation in West Africa[J],2021,15(10).
APA	Fourie, Toscane.,El Bara, Ahmed.,Dubot-Peres, Audrey.,Grard, Gilda.,Briolant, Sebastien.,...&Leparc-Goffart, Isabelle.(2021).Emergence of dengue virus serotype 2 in Mauritania and molecular characterization of its circulation in West Africa.PLOS NEGLECTED TROPICAL DISEASES,15(10).
MLA	Fourie, Toscane,et al."Emergence of dengue virus serotype 2 in Mauritania and molecular characterization of its circulation in West Africa".PLOS NEGLECTED TROPICAL DISEASES 15.10(2021).