干旱区生态环境知识资源中心(Arid): Ethnopharmacology, phytochemistry, agrotechnology, and conservation of Inula racemosa Hook f. - A critically endangered medicinal plant of the western Himalaya

Arid

DOI	10.1016/j.jep.2021.114613
	Ethnopharmacology, phytochemistry, agrotechnology, and conservation of Inula racemosa Hook f. - A critically endangered medicinal plant of the western Himalaya
	Rathore, Shalika; Raj, Yog; Debnath, Pritam; Kumar, Manish; Kumar, Rakesh
通讯作者	Kumar, R (corresponding author), CSIR Inst Himalayan Bioresource Technol, Agrotechnol Div, Palampur 176061, Himachal Prades, India.
来源期刊	JOURNAL OF ETHNOPHARMACOLOGY
ISSN	0378-8741
EISSN	1872-7573
出版年	2022
卷号	283
英文摘要	Ethnopharmacological relevance: Inula racemosa Hook. f., is a critically endangered perennial herb distributed throughout the Himalaya; commercially useful in pharmaceutical products mainly because of its expectorant, antispasmodic, hypotensive, anti-inflammatory, carminative, thermogenic, digestive, cardiotonic, acrid, alexipharmic, anodyne, aphrodisiac, febrifuge, and antiseptic properties. The roots including rhizomes of the plant were used in the treatment of various ailments like chest pain, liver dysfunction, dyspnoea, and cardiovascular diseases by the ethenic Himalayan residents. Aim of the review: Even though there are plentiful studies involving I. racemosa for pharmacological properties, but there is gap or few records available on production technologies and patents. The purpose of review is to provide large unmanageable information in systematic form for researchers, health care contributors, and policy makers so that they efficiently integrate the existing information and provide balanced decision making. Materials and methods: Relevant data search was completed through systematic searches using various scientific databases including e-resources viz., Scopus, Google Scholar, Science Direct, ACS, Springer Link, Taylor and Francis, Scifinder, PubMed, PubChem, Web of Science, LibGen, Wiley, and China National Knowledge Infrastructure (CNKI). The list of literature cited in this review are dated from 1959 to 2021. Results: Till date variety of ethnobotanical and pharmacological properties of essential oil including crude extract of I. racemosa have been documented. The shortlisted records revealed that the herb has a potential to treat stomach ulcer, respiratory tract infections including chronic obstructive pulmonary disease (COPD). Alantolactone and isoalloalantolactone were reported as the major bioactive constituents along with few fatty acids, phytosterols, and glycosides characterized by GC, GC/MS, HPLC, HPTLC and qNMR techniques. Conclusions: Based on a detailed literature survey on the plant, evidences were found fascinating for biological, traditional, and pharmacological effects, whilst there are no genomic resources available for this medicinal herb. Thus, molecular studies are critical for unravelling the production process of bioactive metabolites inside herb, which will underlay a path for improving these metabolites at commercial scale. Moreover, the association and role of particular phytoconstituent in its biological properties still needs to be validated. In addition, there are no reports on measures on its conservation and mechanism of toxicity research, which also needs more attention. We hope this review can provide a basis for further studies concerning the protected and efficient utilization of I. racemosa.
英文关键词	Agrotechnology Alantolactones Ethnopharmacology Isoalantolactones Pushkarmool
类型	Article
语种	英语
收录类别	SCI-E
WOS记录号	WOS:000710234500002
WOS关键词	SECONDARY POLLEN PRESENTATION ; ALLERGIC CONTACT-DERMATITIS ; SESQUITERPENE LACTONES ; IN-VITRO ; COLD DESERT ; ESSENTIAL OIL ; GENUS INULA ; ALANTOLACTONE ; ISOALANTOLACTONE ; EXTRACTS
WOS类目	Plant Sciences ; Chemistry, Medicinal ; Integrative & Complementary Medicine ; Pharmacology & Pharmacy
WOS研究方向	Plant Sciences ; Pharmacology & Pharmacy ; Integrative & Complementary Medicine
资源类型	期刊论文
条目标识符	http://119.78.100.177/qdio/handle/2XILL650/374498
作者单位	[Rathore, Shalika; Raj, Yog; Debnath, Pritam; Kumar, Manish; Kumar, Rakesh] CSIR Inst Himalayan Bioresource Technol, Agrotechnol Div, Palampur 176061, Himachal Prades, India; [Rathore, Shalika; Raj, Yog; Kumar, Rakesh] Acad Sci & Innovat Res AcSIR, Ghaziabad 201002, India
推荐引用方式 GB/T 7714	Rathore, Shalika,Raj, Yog,Debnath, Pritam,et al. Ethnopharmacology, phytochemistry, agrotechnology, and conservation of Inula racemosa Hook f. - A critically endangered medicinal plant of the western Himalaya[J],2022,283.
APA	Rathore, Shalika,Raj, Yog,Debnath, Pritam,Kumar, Manish,&Kumar, Rakesh.(2022).Ethnopharmacology, phytochemistry, agrotechnology, and conservation of Inula racemosa Hook f. - A critically endangered medicinal plant of the western Himalaya.JOURNAL OF ETHNOPHARMACOLOGY,283.
MLA	Rathore, Shalika,et al."Ethnopharmacology, phytochemistry, agrotechnology, and conservation of Inula racemosa Hook f. - A critically endangered medicinal plant of the western Himalaya".JOURNAL OF ETHNOPHARMACOLOGY 283(2022).