干旱区生态环境知识资源中心(Arid): Development of an Analytical Method for Simultaneous Determination of Quinolones and Tetracyclines in Livestock and Fishery Products

Arid

DOI	10.3358/shokueishi.62.168
	Development of an Analytical Method for Simultaneous Determination of Quinolones and Tetracyclines in Livestock and Fishery Products
	Fukumitsu, Toru; Waki, Masumi; Hagio, Masahito; Hayashi, Takako; Kuwahara, Chikako
通讯作者	Fukumitsu, T (corresponding author), Kanagawa Prefectural Inst Publ Hlth, 1-3-1 Shimomachiya, Chigasaki, Kanagawa 2530087, Japan.
来源期刊	FOOD HYGIENE AND SAFETY SCIENCE
ISSN	0015-6426
出版年	2021
卷号	62 期号:5 页码:168-174
英文摘要	In this study, we developed an analytical method for simultaneous determination of 14 quino-lones and 4 tetracyclines in livestock and fishery products using LC-MS/MS. The analytes were extracted from food samples with citrate buffer (containing EDTA) -methanol-acetonitrile (3 : 1 : 1, v/v/v) in the presence of n-hexane, and the extract was purified with an Oasis PRIME HLB cartridge column. It was suggested that this analytical method can also extract analytes from solid samples containing fat by using n -hexane. In addition, using methanol-acetonitrile (3 : 7, v/v) containing 0.1 vol% formic acid as an eluent from the cartridge column, the purification effect could be improved, while minimizing the impairment of the recovery rate. As a result of the validation using six types of food samples, trueness (accuracy) was 70.6%-113.8%, the RSD of repeatability was 9.0% or less, and the RSD of within-laboratory reproducibility was 15.5% or less. Using this approach, the standard values mentioned in the Japanese guideline were successfully met.
英文关键词	quinolone tetracycline veterinary drug LC-MS/MS livestock and fishery product
类型	Article
语种	日语
收录类别	SCI-E
WOS记录号	WOS:000718939400006
WOS关键词	PERFORMANCE LIQUID-CHROMATOGRAPHY ; VETERINARY DRUGS ; FLUORESCENCE ; METABOLITE ; MILOXACIN
WOS类目	Food Science & Technology
WOS研究方向	Food Science & Technology
资源类型	期刊论文
条目标识符	http://119.78.100.177/qdio/handle/2XILL650/373651
作者单位	[Fukumitsu, Toru; Waki, Masumi; Hagio, Masahito; Hayashi, Takako; Kuwahara, Chikako] Kanagawa Prefectural Inst Publ Hlth, 1-3-1 Shimomachiya, Chigasaki, Kanagawa 2530087, Japan
推荐引用方式 GB/T 7714	Fukumitsu, Toru,Waki, Masumi,Hagio, Masahito,et al. Development of an Analytical Method for Simultaneous Determination of Quinolones and Tetracyclines in Livestock and Fishery Products[J],2021,62(5):168-174.
APA	Fukumitsu, Toru,Waki, Masumi,Hagio, Masahito,Hayashi, Takako,&Kuwahara, Chikako.(2021).Development of an Analytical Method for Simultaneous Determination of Quinolones and Tetracyclines in Livestock and Fishery Products.FOOD HYGIENE AND SAFETY SCIENCE,62(5),168-174.
MLA	Fukumitsu, Toru,et al."Development of an Analytical Method for Simultaneous Determination of Quinolones and Tetracyclines in Livestock and Fishery Products".FOOD HYGIENE AND SAFETY SCIENCE 62.5(2021):168-174.