干旱区生态环境知识资源中心(Arid): Emerging diversity and ongoing expansion of the genus Brucella

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DOI	10.1016/j.meegid.2021.104865
	Emerging diversity and ongoing expansion of the genus Brucella
	Whatmore, Adrian M.; Foster, Jeffrey T.
通讯作者	Whatmore, AM (corresponding author), Anim & Plant Hlth Agcy APHA, OIE & FAO Brucellosis Reference Lab, Dept Bacteriol, Woodham Lane, Addlestone, Surrey, England.
来源期刊	INFECTION GENETICS AND EVOLUTION
ISSN	1567-1348
EISSN	1567-7257
出版年	2021
卷号	92
英文摘要	Remarkable genetic diversity and breadth of host species has been uncovered in the Brucella genus over the past decade, fundamentally changing our concept of what it means to be a Brucella. From ocean fishes and marine mammals, to pond dwelling amphibians, forest foxes, desert rodents, and cave-dwelling bats, Brucella have revealed a variety of previously unknown niches. Classical microbiological techniques have been able to help us classify many of these new strains but at times have limited our ability to see the true relationships among or within species. The closest relatives of Brucella are soil bacteria and the adaptations of Brucella spp. to live intracellularly suggest that the genus has evolved to live in vertebrate hosts. Several recently discovered species appear to have phenotypes that are intermediate between soil bacteria and core Brucella, suggesting that they may represent ancestral traits that were subsequently lost in the traditional species. Remarkably, the broad relationships among Brucella species using a variety of sequence and fragment-based approaches have been upheld when using comparative genomics with whole genomes. Nonetheless, genomes are required for fine-scale resolution of many of the relationships and for understanding the evolutionary history of the genus. We expect that the coming decades will reveal many more hosts and previously unknown diversity in a wide range of environments.
英文关键词	Brucella Brucellosis Zoonoses MLVA MLSA Genomics
类型	Review
语种	英语
收录类别	SCI-E
WOS记录号	WOS:000733833000009
WOS关键词	SUIS BIOVAR 2 ; TANDEM-REPEAT ANALYSIS ; MULTIPLEX PCR ASSAY ; SINGLE-NUCLEOTIDE POLYMORPHISMS ; VARIABLE-NUMBER ; MOLECULAR EPIDEMIOLOGY ; GENETIC DIVERSITY ; MELITENSIS STRAINS ; GENOME SEQUENCE ; VACCINE STRAINS
WOS类目	Infectious Diseases
WOS研究方向	Infectious Diseases
资源类型	期刊论文
条目标识符	http://119.78.100.177/qdio/handle/2XILL650/373609
作者单位	[Whatmore, Adrian M.] Anim & Plant Hlth Agcy APHA, OIE & FAO Brucellosis Reference Lab, Dept Bacteriol, Woodham Lane, Addlestone, Surrey, England; [Foster, Jeffrey T.] No Arizona Univ, Pathogen & Microbiome Inst, Flagstaff, AZ 86011 USA
推荐引用方式 GB/T 7714	Whatmore, Adrian M.,Foster, Jeffrey T.. Emerging diversity and ongoing expansion of the genus Brucella[J],2021,92.
APA	Whatmore, Adrian M.,&Foster, Jeffrey T..(2021).Emerging diversity and ongoing expansion of the genus Brucella.INFECTION GENETICS AND EVOLUTION,92.
MLA	Whatmore, Adrian M.,et al."Emerging diversity and ongoing expansion of the genus Brucella".INFECTION GENETICS AND EVOLUTION 92(2021).