干旱区生态环境知识资源中心(Arid): Antioxidant, Anti-alpha-amylase and Antimicrobial Activities of Doum (Hyphaene thebaica) and Argun (Medemia argun) Fruit Parts

Arid

DOI	10.3923/ijp.2019.953.961
	Antioxidant, Anti-alpha-amylase and Antimicrobial Activities of Doum (Hyphaene thebaica) and Argun (Medemia argun) Fruit Parts
	Atito, Eman; Moustafa, Mahmoud F.; Siddiqui, S.; El-Sayed, Magdi
通讯作者	El-Sayed, M (corresponding author), Aswan Univ, Fac Sci, Dept Bot, Aswan 81528, Egypt.
来源期刊	INTERNATIONAL JOURNAL OF PHARMACOLOGY
ISSN	1811-7775
EISSN	1812-5700
出版年	2019
卷号	15 期号:8 页码:953-961
英文摘要	Background and Objectives: Doum (Hyphaene thebaica) is a common palm tree in Egypt and produce an edible fresh fruits or dried in refreshment drinks. Another relative desert uncommon palm, Argun (Medemia argun) deserves extra focus as its fruits were found reserved in Pharaohs tombs. This study is designated to examine the phytochemicals, nutrient content, antioxidant and antimicrobial inhibitions activities of fruit parts of H thebaica (HT) and M argun (MAR). Materials and Methods: The total phenolic and flavonoid contents of fruit parts (mesocarp (M), coat (C) and seed endocarp (E)) were investigated spectrophotometrically. Antioxidant properties were measured as total antioxidant capacity, DPPH and H2O2 scavenging. The nutritional values determined as carbohydrates, proteins contents and anti-alpha-amylase activities. A bioassay based on inhibition zone on agar plate was applied to evaluate the antibiotic activity of the HT and MAR metabolites against 4 pathogenic bacterial strains. Results:The results displayed that antioxidant, antibacterial activities and nutritional values differ significantly in the endocarp, mesocarp and coat samples of both fruits. Flavonoids and phenolics content are high in endocarp of each fruit and low in mesocarp. Total phenolics from fruits parts ranged between 40.65-327.48 mg GAE g(-1) of dry sample. The IC50 values for radical scavenging of DPPH of MARE, MARM, MARC, HTE, HTM and HTC were 55.01, >500, 293.36, 53.76, >500 and 137.89 mu g mL(-1), respectively. The hydrogen peroxide scavenging efficacy of the various extracts obtained from HT and MAR was in the order of HTE>MARE>MARC>HTC>HTM>MARM. IC50 inhibitory activity of alpha-amylase showed the maximum in HT mesocarp, followed by HT coat and HT endocarp. At the concentrations of 100, 200, 300, 400 and 500 mu g mL(-1), HT mesocarp (HTM) showed inhibitory activity of 61.57, 85.67, 86.93, 83.97 and 85.20%, respectively and while MAR mesocarp (MARM) was 60.67, 64.13, 83.83, 82.23 and 82.27%, respectively. HTE and MARE extracts possess potential antioxidant and antibacterial properties followed by HT coat (HTC) and MAR coat (MARC). Conclusion: Argun fruit has strong biological activities similar to doum fruits and potentially can be used as food dietary supplement to cure cancer and diabetic diseases.
英文关键词	Antioxidants Hyphaene thebaica Medemia argun nutrient corn positions antibacterial activity
类型	Article
语种	英语
收录类别	SCI-E
WOS记录号	WOS:000500290200007
WOS关键词	PALM
WOS类目	Pharmacology & Pharmacy
WOS研究方向	Pharmacology & Pharmacy
资源类型	期刊论文
条目标识符	http://119.78.100.177/qdio/handle/2XILL650/369629
作者单位	[Atito, Eman; El-Sayed, Magdi] Aswan Univ, Fac Sci, Dept Bot, Aswan 81528, Egypt; [Moustafa, Mahmoud F.; Siddiqui, S.] King Khalid Univ, Coll Sci, Dept Biol, Abha 9004, Saudi Arabia; [Moustafa, Mahmoud F.] South Valley Univ, Dept Bot, Fac Sci, Qena, Egypt; [El-Sayed, Magdi] Aswan Univ, Unit Environm Studies & Dev, Aswan 81528, Egypt
推荐引用方式 GB/T 7714	Atito, Eman,Moustafa, Mahmoud F.,Siddiqui, S.,et al. Antioxidant, Anti-alpha-amylase and Antimicrobial Activities of Doum (Hyphaene thebaica) and Argun (Medemia argun) Fruit Parts[J],2019,15(8):953-961.
APA	Atito, Eman,Moustafa, Mahmoud F.,Siddiqui, S.,&El-Sayed, Magdi.(2019).Antioxidant, Anti-alpha-amylase and Antimicrobial Activities of Doum (Hyphaene thebaica) and Argun (Medemia argun) Fruit Parts.INTERNATIONAL JOURNAL OF PHARMACOLOGY,15(8),953-961.
MLA	Atito, Eman,et al."Antioxidant, Anti-alpha-amylase and Antimicrobial Activities of Doum (Hyphaene thebaica) and Argun (Medemia argun) Fruit Parts".INTERNATIONAL JOURNAL OF PHARMACOLOGY 15.8(2019):953-961.