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	Assessment of In Vitro Antimicrobial and Anti-breast Cancer Activities of Extracts Isolated from Desert Truffles in Saudi Arabia
	Elsayed, E. A.; Alsahli, F. D.; Barakat, I. A.; El Enshasy, H. A.; Wadaan, M. A.
通讯作者	Elsayed, EA (corresponding author), King Saud Univ, Coll Sci, Zool Dept, Bioprod Res Chair, Riyadh 11451, Saudi Arabia. ; Elsayed, EA (corresponding author), Natl Res Ctr, Nat & Microbial Prod Dept, Cairo 12311, Egypt.
来源期刊	JOURNAL OF SCIENTIFIC & INDUSTRIAL RESEARCH
ISSN	0022-4456
EISSN	0975-1084
出版年	2019
卷号	78 期号:7 页码:419-425
英文摘要	Truffles are consumed worldwide as a type of precious food. Desert truffles are characterized by their growth under extreme soil and climate conditions. They have numerous nutritional and medicinal applications. Desert truffles have been shown to exhibit various biological activities. During the present work, we identified two truffle types collected from Riyadh Province, Kingdom of Saudi Arabia, as Tirmania nivea and Terfezia claveryi. Their extracts showed significant antimicrobial activity against Bacillus subtilis, while the activity was less obvious against Escherichia coli. Hexane and ethyl acetate extracts of both types showed a dose-dependent effect against MCF-7 cancer cells, where their highest toxicities ranged from 91-93%. The lowest effective IC50 values were 378.9 +/- 0.96 and 215.8 +/- 0.92 mu g/mL for T. nivea and T. claveryi, respectively.
英文关键词	Desert truffles Antimicrobial Anticancer MCF-7 Solvent extraction
类型	Article
语种	英语
收录类别	SCI-E
WOS记录号	WOS:000491213500005
WOS关键词	ANTIOXIDANT ; ANTICANCER
WOS类目	Engineering, Multidisciplinary
WOS研究方向	Engineering
来源机构	King Saud University
资源类型	期刊论文
条目标识符	http://119.78.100.177/qdio/handle/2XILL650/369532
作者单位	[Elsayed, E. A.; Wadaan, M. A.] King Saud Univ, Coll Sci, Zool Dept, Bioprod Res Chair, Riyadh 11451, Saudi Arabia; [Elsayed, E. A.] Natl Res Ctr, Nat & Microbial Prod Dept, Cairo 12311, Egypt; [Alsahli, F. D.; Barakat, I. A.] King Saud Univ, Coll Sci, Zool Dept, Riyadh 11451, Saudi Arabia; [Alsahli, F. D.] KACST, Natl Ctr Genome Technol, Life Sci & Environm Res Inst, Riyadh, Saudi Arabia; [El Enshasy, H. A.] Univ Teknol Malaysia, Inst Bioprod Dev, Johor Baharu 81310, Malaysia; [El Enshasy, H. A.] City Sci Res & Technol Applicat, Alexandria 21934, Egypt
推荐引用方式 GB/T 7714	Elsayed, E. A.,Alsahli, F. D.,Barakat, I. A.,et al. Assessment of In Vitro Antimicrobial and Anti-breast Cancer Activities of Extracts Isolated from Desert Truffles in Saudi Arabia[J]. King Saud University,2019,78(7):419-425.
APA	Elsayed, E. A.,Alsahli, F. D.,Barakat, I. A.,El Enshasy, H. A.,&Wadaan, M. A..(2019).Assessment of In Vitro Antimicrobial and Anti-breast Cancer Activities of Extracts Isolated from Desert Truffles in Saudi Arabia.JOURNAL OF SCIENTIFIC & INDUSTRIAL RESEARCH,78(7),419-425.
MLA	Elsayed, E. A.,et al."Assessment of In Vitro Antimicrobial and Anti-breast Cancer Activities of Extracts Isolated from Desert Truffles in Saudi Arabia".JOURNAL OF SCIENTIFIC & INDUSTRIAL RESEARCH 78.7(2019):419-425.