干旱区生态环境知识资源中心(Arid): Kidney progression project (KiPP): Protocol for a longitudinal cohort study of progression in chronic kidney disease of unknown etiology in Sri Lanka

Arid

DOI	10.1080/17441692.2018.1508480
	Kidney progression project (KiPP): Protocol for a longitudinal cohort study of progression in chronic kidney disease of unknown etiology in Sri Lanka
	Vlahos, Penny; Schensul, Stephen L.; Nanayakkara, Nishantha; Chandrajith, Rohana; Haider, Lalarukh; Anand, Shuchi; Silva, Kalinga Tudor; Schensul, Jean J.
通讯作者	Vlahos, P (corresponding author), Univ Connecticut, Dept Marine Sci, 1080 Shennecossett Rd, Groton, CT 06340 USA.
来源期刊	GLOBAL PUBLIC HEALTH
ISSN	1744-1692
EISSN	1744-1706
出版年	2019
卷号	14 期号:2 页码:214-226
英文摘要	Over the last two decades, a global epidemic of chronic kidney disease of unknown etiology (CKDu) has emerged in rural, arid, agricultural, lowland areas. Endemic regions have reported 15 to 20% prevalence among residents aged 30-60 years. CKDu is a progressive and irreversible disease resulting in renal failure and death in the absence of dialysis or a kidney transplant. While much of the research has focused on identifying etiology, this project seeks to ascertain factors associated with the rapidity of kidney disease progression in one of Sri Lanka's CKDu endemic areas. A sample of 296 male and female residents aged 21 to 65 with moderate CKD, as measured by their serum creatinine level, and a clinical diagnosis of CKDu are followed using quarterly serum testing to track the rate of progression. A baseline survey administered to the entire sample addresses potential risk factors, supplemented by a short survey focusing on changes through time. Concurrently water, soil and air are tested at the local and household levels. The study is the first to foster a multi-disciplinary approach that focuses on disease progression, identifying behavioural and exposure risk factors for rapid kidney function decline, in this progressively fatal disease.
英文关键词	CKDu kidney disease progression agriculture contaminants
类型	Article
语种	英语
开放获取类型	Green Accepted
收录类别	SSCI
WOS记录号	WOS:000456387700005
WOS关键词	UNCERTAIN ETIOLOGY ; TRACE-ELEMENTS ; HEAT-STRESS ; NEPHROPATHY ; EXPOSURES ; RISK ; CKDU
WOS类目	Public, Environmental & Occupational Health
WOS研究方向	Public, Environmental & Occupational Health
资源类型	期刊论文
条目标识符	http://119.78.100.177/qdio/handle/2XILL650/369449
作者单位	[Vlahos, Penny] Univ Connecticut, Dept Marine Sci, 1080 Shennecossett Rd, Groton, CT 06340 USA; [Schensul, Stephen L.; Haider, Lalarukh] Univ Connecticut, Sch Med, Storrs, CT 06268 USA; [Nanayakkara, Nishantha] Univ Peradeniya, Kandy Teaching Hosp, Fac Med, Kandy, Sri Lanka; [Chandrajith, Rohana] Univ Peradeniya, Dept Geol, Kandy, Sri Lanka; [Silva, Kalinga Tudor] Univ Peradeniya, Dept Sociol, Kandy, Sri Lanka; [Anand, Shuchi] Stanford Univ, Sch Med, Stanford, CA 94305 USA; [Schensul, Jean J.] Inst Community Res, Hartford, CT USA
推荐引用方式 GB/T 7714	Vlahos, Penny,Schensul, Stephen L.,Nanayakkara, Nishantha,et al. Kidney progression project (KiPP): Protocol for a longitudinal cohort study of progression in chronic kidney disease of unknown etiology in Sri Lanka[J],2019,14(2):214-226.
APA	Vlahos, Penny.,Schensul, Stephen L..,Nanayakkara, Nishantha.,Chandrajith, Rohana.,Haider, Lalarukh.,...&Schensul, Jean J..(2019).Kidney progression project (KiPP): Protocol for a longitudinal cohort study of progression in chronic kidney disease of unknown etiology in Sri Lanka.GLOBAL PUBLIC HEALTH,14(2),214-226.
MLA	Vlahos, Penny,et al."Kidney progression project (KiPP): Protocol for a longitudinal cohort study of progression in chronic kidney disease of unknown etiology in Sri Lanka".GLOBAL PUBLIC HEALTH 14.2(2019):214-226.