干旱区生态环境知识资源中心(Arid): Structural and Functional Characteristics of miRNAs in Five Strategic Millet Species and Their Utility in Drought Tolerance

Arid

DOI	10.3389/fgene.2020.608421
	Structural and Functional Characteristics of miRNAs in Five Strategic Millet Species and Their Utility in Drought Tolerance
	Chakraborty, Animikha; Viswanath, Aswini; Malipatil, Renuka; Rathore, Abhishek; Thirunavukkarasu, Nepolean
通讯作者	Thirunavukkarasu, N (corresponding author), Indian Council Agr Res, Genom & Mol Breeding Lab, Indian Inst Millets Res, Hyderabad, India. ; Rathore, A (corresponding author), Int Crops Res Inst Semi Arid Trop, Stat Bioinformat & Data Management, Hyderabad, India.
来源期刊	FRONTIERS IN GENETICS
EISSN	1664-8021
出版年	2020
卷号	11
英文摘要	Millets are the strategic food crops in arid and drought-prone ecologies. Millets, by virtue of nature, are very well-adapted to drought conditions and able to produce sustainable yield. Millets have important nutrients that can help prevent micro-nutrient malnutrition. As a result of the adverse effect of climate change and widespread malnutrition, millets have attained a strategic position to sustain food and nutritional security. Although millets can adapt well to the drought ecologies where other cereals fail completely, the yield level is very low under stress. There is a tremendous opportunity to increase the genetic potential of millet crops in dry lands when the genetics of the drought-tolerance mechanism is fully explained. MicroRNAs (miRNAs) are the class of small RNAs that control trait expression. They are part of the gene regulation but little studied in millets. In the present study, novel miRNAs and gene targets were identified from the genomic resources of pearl millet, sorghum, foxtail millet, finger millet, and proso millet through in silico approaches. A total of 1,002 miRNAs from 280 families regulating 23,158 targets were identified using different filtration criteria in five millet species. The unique as well as conserved structural features and functional characteristics of miRNA across millets were explained. About 84 miRNAs were conserved across millets in different species combinations, which explained the evolutionary relationship of the millets. Further, 215 miRNAs controlling 155 unique major drought-responsive genes, transcription factors, and protein families revealed the genetics of drought tolerance that are accumulated in the millet genomes. The miRNAs regulating the drought stress through specific targets or multiple targets showed through a network analysis. The identified genes regulated by miRNA genes could be useful in developing functional markers and used for yield improvement under drought in millets as well as in other crops.
英文关键词	microRNAs millets drought stress conserved genes functional genes
类型	Article
语种	英语
开放获取类型	Green Accepted, gold, Green Published
收录类别	SCI-E
WOS记录号	WOS:000600643700001
WOS关键词	COMPUTATIONAL IDENTIFICATION ; MICRORNAS ; STRESS ; ARABIDOPSIS ; EXPRESSION ; GENE ; EVOLUTION ; TARGETS ; RESISTANCE ; ROLES
WOS类目	Genetics & Heredity
WOS研究方向	Genetics & Heredity
来源机构	International Crops Research Institute for the Semi-Arid Tropics
资源类型	期刊论文
条目标识符	http://119.78.100.177/qdio/handle/2XILL650/369194
作者单位	[Chakraborty, Animikha; Viswanath, Aswini; Malipatil, Renuka; Thirunavukkarasu, Nepolean] Indian Council Agr Res, Genom & Mol Breeding Lab, Indian Inst Millets Res, Hyderabad, India; [Rathore, Abhishek] Int Crops Res Inst Semi Arid Trop, Stat Bioinformat & Data Management, Hyderabad, India
推荐引用方式 GB/T 7714	Chakraborty, Animikha,Viswanath, Aswini,Malipatil, Renuka,et al. Structural and Functional Characteristics of miRNAs in Five Strategic Millet Species and Their Utility in Drought Tolerance[J]. International Crops Research Institute for the Semi-Arid Tropics,2020,11.
APA	Chakraborty, Animikha,Viswanath, Aswini,Malipatil, Renuka,Rathore, Abhishek,&Thirunavukkarasu, Nepolean.(2020).Structural and Functional Characteristics of miRNAs in Five Strategic Millet Species and Their Utility in Drought Tolerance.FRONTIERS IN GENETICS,11.
MLA	Chakraborty, Animikha,et al."Structural and Functional Characteristics of miRNAs in Five Strategic Millet Species and Their Utility in Drought Tolerance".FRONTIERS IN GENETICS 11(2020).