干旱区生态环境知识资源中心(Arid): Profiles of antibiotic resistance genes in an inland salt-lake Ebinur Lake, Xinjiang, China: The relationship with antibiotics, environmental factors, and microbial communities

Arid

DOI	10.1016/j.ecoenv.2021.112427
	Profiles of antibiotic resistance genes in an inland salt-lake Ebinur Lake, Xinjiang, China: The relationship with antibiotics, environmental factors, and microbial communities
	Wang, Yongqiang; Lu, Shaoyong; Liu, Xiaohui; Chen, Jing; Han, Maozhen; Wang, Zhi; Guo, Wei
通讯作者	Lu, SY ; Liu, XH (corresponding author), Chinese Res Inst Environm Sci, Res Ctr Lake Environm,State Environm Protect Key, State Key Lab Environm Criteria & Risk Assessment, Natl Engn Lab Lake Pollut Control & Ecol Restorat, Beijing 100012, Peoples R China.
来源期刊	ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY
ISSN	0147-6513
EISSN	1090-2414
出版年	2021
卷号	221
英文摘要	Lakes in arid northwestern China, as the main pollutant-holding water bodies in the typical ecologically fragile areas, are facing the unknown risk of exposure to antibiotics and antibiotic resistance genes (ARGs). In this study, five ARGs and one mobile genetic element (intI1) and their relation with antibiotics, microbial communities and water quality were investigated in Ebinur Lake Basin, a typical salt-lake of China. Quantitative PCR analysis indicated that ARGs decreasing order in both surface water and sediment was sul1 sul2 >tetW>ermB>qnrS, which means sulfonamide resistance genes were the main pollution ARGs. Macrolide antibiotics were the predominant antibiotics in the surface water and sediment in winter, while sulfonamides and quinolones accounted for a high proportion in summer. There was a non-corresponding relationship between ARGs and antibiotics. Moreover, the relationship between ARGs and microbial communities were defined. Sulfonamide resistance genes were carried by a greater diversity of potential host bacteria (76 genera) than other ARGs (9 genera). And their positive correlation with intI1 (p < 0.05) which promotes their migration and provides possibility of their co-occurrence in bacterial populations (e.g., Nitrospira). Bacterial genera were the main driver of ARGs distribution pattern in highly saline lake sediment. Environmental factors like salinity, total nitrogen and organic matter could have a certain influence on the occurrence of ARGs by affecting microorganisms. The results systematically show the distribution and propagation characteristics of ARGs in typical inland salt-lakes in China, and preliminarily explored the relationship between ARGs and antibiotics, resistance genes and microorganisms in lakes in ecologically fragile areas.
英文关键词	Ebinur Lake Basin Antibiotics Antibiotic resistance genes Microbial community
类型	Article
语种	英语
开放获取类型	gold
收录类别	SCI-E
WOS记录号	WOS:000669485700011
WOS关键词	PEARL RIVER ESTUARY ; WASTE-WATER ; BACTERIAL COMMUNITY ; ORGANIC-MATTER ; EUTROPHIC LAKE ; SEDIMENT ; SURFACE ; DIVERSITY ; REMOVAL ; IMPACT
WOS类目	Environmental Sciences ; Toxicology
WOS研究方向	Environmental Sciences & Ecology ; Toxicology
来源机构	清华大学
资源类型	期刊论文
条目标识符	http://119.78.100.177/qdio/handle/2XILL650/368454
作者单位	[Wang, Yongqiang; Lu, Shaoyong; Liu, Xiaohui] Chinese Res Inst Environm Sci, Res Ctr Lake Environm,State Environm Protect Key, State Key Lab Environm Criteria & Risk Assessment, Natl Engn Lab Lake Pollut Control & Ecol Restorat, Beijing 100012, Peoples R China; [Wang, Yongqiang] Harbin Inst Technol, State Key Lab Urban Water Resource & Environm, Harbin 150090, Peoples R China; [Liu, Xiaohui] Tsinghua Univ, Beijing 100084, Peoples R China; [Chen, Jing] Wuhan Polytech Univ, Coll Biol & Pharmaceut Engn, Wuhan 430023, Peoples R China; [Han, Maozhen] Anhui Med Univ, Sch Life Sci, Hefei 230032, Peoples R China; [Wang, Zhi] Chinese Acad Sci, Inst Geodesy & Geophys, Key Lab Environm & Disaster Monitoring & Evaluat, Wuhan 430077, Hubei, Peoples R China; [Guo, Wei] Beijing Univ Technol, Coll Environm & Energy Engn, Beijing 100124, Peoples R China
推荐引用方式 GB/T 7714	Wang, Yongqiang,Lu, Shaoyong,Liu, Xiaohui,et al. Profiles of antibiotic resistance genes in an inland salt-lake Ebinur Lake, Xinjiang, China: The relationship with antibiotics, environmental factors, and microbial communities[J]. 清华大学,2021,221.
APA	Wang, Yongqiang.,Lu, Shaoyong.,Liu, Xiaohui.,Chen, Jing.,Han, Maozhen.,...&Guo, Wei.(2021).Profiles of antibiotic resistance genes in an inland salt-lake Ebinur Lake, Xinjiang, China: The relationship with antibiotics, environmental factors, and microbial communities.ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY,221.
MLA	Wang, Yongqiang,et al."Profiles of antibiotic resistance genes in an inland salt-lake Ebinur Lake, Xinjiang, China: The relationship with antibiotics, environmental factors, and microbial communities".ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY 221(2021).