干旱区生态环境知识资源中心(Arid): Simultaneous Determination of Albendazole and Its Three Metabolites in Pig and Poultry Muscle by Ultrahigh-Performance Liquid Chromatography-Fluorescence Detection

Arid

DOI	10.3390/foods10102350
	Simultaneous Determination of Albendazole and Its Three Metabolites in Pig and Poultry Muscle by Ultrahigh-Performance Liquid Chromatography-Fluorescence Detection
	He, Zhaoyuan; Diao, Zhixiang; Guo, Yawen; Xie, Kaizhou; Chen, Lan; Xue, Chun; Lu, Yang; Chen, Jinyuan; Zhang, Tao
通讯作者	Xie, KZ (corresponding author), Yangzhou Univ, Coll Anim Sci & Technol, Yangzhou 225009, Jiangsu, Peoples R China. ; Xie, KZ (corresponding author), Yangzhou Univ, Joint Int Res Lab Agr & Agriprod Safety, Yangzhou 225009, Jiangsu, Peoples R China.
来源期刊	FOODS
EISSN	2304-8158
出版年	2021
卷号	10 期号:10
英文摘要	A fast, simple and efficient ultrahigh-performance liquid chromatography-fluorescence detection (UPLC-FLD) method for the determination of residues of albendazole (ABZ) and its three metabolites, albendazole sulfone (ABZ-SO2), albendazole sulfoxide (ABZ-SO), and albendazole-2-aminosulfone (ABZ-2NH(2)-SO2), in pig and poultry muscle (chicken, duck and goose) was established. The samples were extracted with ethyl acetate, and the extracts were further subjected to cleanup by utilizing a series of liquid-liquid extraction (LLE) steps. Then, extracts were purified by OASIS(R) PRiME hydrophilic-lipophilic balance (HLB) solid-phase extraction (SPE) cartridges (60 mg/3 mL). The target compounds were separated on an ACQUITY UPLC(R) BEH C-18 (2.1 mm x 100 mm, 1.7 mu m) chromatographic column, using a mobile phase composed of 31% acetonitrile and 69% aqueous solution (containing 0.2% formic acid and 0.05% triethylamine). The limits of detection (LODs) and limits of quantification (LOQs) of the four target compounds in pig and poultry muscle were 0.2-3.8 mu g/kg and 1.0-10.9 mu g/kg, respectively. The recoveries were all above 80.37% when the muscle samples were spiked with the four target compounds at the LOQ, 0.5 maximum residue limit (MRL), 1.0 MRL, and 2.0 MRL levels. The intraday relative standard deviations (RSDs) were less than 5.11%, and the interday RSDs were less than 6.29%.
英文关键词	ultrahigh-performance liquid chromatography-fluorescence detection (UPLC-FLD) albendazole (ABZ) and its three metabolites pig muscle poultry muscle
类型	Article
语种	英语
开放获取类型	gold, Green Published
收录类别	SCI-E
WOS记录号	WOS:000712870400001
WOS关键词	TANDEM MASS-SPECTROMETRY ; BENZIMIDAZOLE ANTHELMINTICS ; SAMPLE PREPARATION ; MARKER RESIDUE ; RAT PLASMA ; QUANTIFICATION ; EXTRACTION ; MILK ; HPLC ; MICROEXTRACTION
WOS类目	Food Science & Technology
WOS研究方向	Food Science & Technology
资源类型	期刊论文
条目标识符	http://119.78.100.177/qdio/handle/2XILL650/368362
作者单位	[He, Zhaoyuan; Diao, Zhixiang; Guo, Yawen; Xie, Kaizhou; Xue, Chun; Lu, Yang; Chen, Jinyuan; Zhang, Tao] Yangzhou Univ, Coll Anim Sci & Technol, Yangzhou 225009, Jiangsu, Peoples R China; [He, Zhaoyuan; Diao, Zhixiang; Guo, Yawen; Xie, Kaizhou; Chen, Lan; Xue, Chun; Lu, Yang; Chen, Jinyuan; Zhang, Tao] Yangzhou Univ, Joint Int Res Lab Agr & Agriprod Safety, Yangzhou 225009, Jiangsu, Peoples R China; [Chen, Lan] Yangzhou Univ, Coll Vet Med, Yangzhou 225009, Jiangsu, Peoples R China
推荐引用方式 GB/T 7714	He, Zhaoyuan,Diao, Zhixiang,Guo, Yawen,et al. Simultaneous Determination of Albendazole and Its Three Metabolites in Pig and Poultry Muscle by Ultrahigh-Performance Liquid Chromatography-Fluorescence Detection[J],2021,10(10).
APA	He, Zhaoyuan.,Diao, Zhixiang.,Guo, Yawen.,Xie, Kaizhou.,Chen, Lan.,...&Zhang, Tao.(2021).Simultaneous Determination of Albendazole and Its Three Metabolites in Pig and Poultry Muscle by Ultrahigh-Performance Liquid Chromatography-Fluorescence Detection.FOODS,10(10).
MLA	He, Zhaoyuan,et al."Simultaneous Determination of Albendazole and Its Three Metabolites in Pig and Poultry Muscle by Ultrahigh-Performance Liquid Chromatography-Fluorescence Detection".FOODS 10.10(2021).