干旱区生态环境知识资源中心(Arid): Bioactive principles in exudate gel from the leaf of Aloe fleurentiniorum, traditionally used as folkloric medicine by local people of Aridah and Fayfa mountains, Saudi Arabia

Arid

DOI	10.1016/j.arabjc.2021.103400
	Bioactive principles in exudate gel from the leaf of Aloe fleurentiniorum, traditionally used as folkloric medicine by local people of Aridah and Fayfa mountains, Saudi Arabia
	Moni, Sivakumar Sivagurunathan; Sultan, Muhammad H.; Makeen, Hafiz A.; Madkhali, Osama A.; Bakkari, Mohammed Ali; Alqahtani, Saad S.; Alshahrani, Saeed; Menachery, Santhosh Joseph; Alam, M. Intakhab; Elmobark, Mohamed Eltaib; Rehman, Zia ur; Alam, Md Shamsher; Faqihi, Abdulrahman Yahya; Mogaidi, Hassan Mansour; Khobrani, Hussein; Albana, Essa; Sharahily, Ahmed Mutib
通讯作者	Moni, SS (corresponding author), Jazan Univ, Coll Pharm, Dept Pharmaceut, Jazan, Saudi Arabia.
来源期刊	ARABIAN JOURNAL OF CHEMISTRY
ISSN	1878-5352
EISSN	1878-5379
出版年	2021
卷号	14 期号:11
英文摘要	Aloe fleurentiniorum is a desert plant that is occasionally used to treat wounds by local people of Aridah and Fayfa mountains in Saudi Arabia. However, medicinal value of the plant has not been scientifically established. The purpose of this study was to determine the bioactive phytocomponents contained in the exudate gel (EG) from the leaves of Aloe fleurentiniorum using GCMS and FT-IR studies, as well as antibacterial assays. Medicinally important bioactive compounds were identified using GC-MS analysis. The bioactive compounds are pregn-5-ene-3 alpha,20-diol, 16 alpha-methyl-pregnane-11,20-dione, 3-hydroxy-(3 alpha,5 alpha)-, ursodeoxycholic acid, ``1-heptatriacot anol, allopregnane-7 alpha,11 alpha-diol-3,20-dione, D-arabino-hexopyranoside, 2-octadecenoic acid methyl ester, D-ribo-hexose,2,6-dideoxy-3-O-methyl glucosamine, N-acetyl-N-benzoyl-alpha-D-glucopyranoside, nonyl 1-thio pregnenolone, 5-cholestene-3-ol, 24-methyl-cholestanol, and D-allose hexadecanoic acid methyl ester. Furthermore, specific groups and their respective chemical compounds were identified via FT-IR spectroscopy studies. The FT-IR spectroscopy of EG showed various functional groups at 3354, 2945, 2832, 2523, 2046, 1707, 1451, 1108, 1031, 880, 737 and 610 cm(-1). The FT-IR peaks revealed the likely presence of various compounds such as glycosides, flavonoids, steroids, saponins, flavonoids, amino sugars, cutin and isothiocyanate. Moreover, EG produced a wide range of antibacterial effects on some screened human pathogenic bacteria. (C) 2021 The Author(s). Published by Elsevier B.V. on behalf of King Saud University.
英文关键词	Desert plant Aloe fleurentiniorum Bioactive constituents Anti-bacterial activity
类型	Article
语种	英语
开放获取类型	gold
收录类别	SCI-E
WOS记录号	WOS:000712533800009
WOS关键词	D-ALLOSE ; EXTRACT ; PLANTS ; ACID ; STEM
WOS类目	Chemistry, Multidisciplinary
WOS研究方向	Chemistry
资源类型	期刊论文
条目标识符	http://119.78.100.177/qdio/handle/2XILL650/368215
作者单位	[Moni, Sivakumar Sivagurunathan; Sultan, Muhammad H.; Madkhali, Osama A.; Bakkari, Mohammed Ali; Alam, M. Intakhab; Elmobark, Mohamed Eltaib] Jazan Univ, Coll Pharm, Dept Pharmaceut, Jazan, Saudi Arabia; [Makeen, Hafiz A.; Alqahtani, Saad S.; Menachery, Santhosh Joseph] Jazan Univ, Coll Pharm, Clin Pharm Dept, Pharm Practice Res Unit, Jazan, Saudi Arabia; [Alqahtani, Saad S.] Jazan Univ, Coll Pharm, Dept Pharmacol & Toxicol, Jazan, Saudi Arabia; [Rehman, Zia ur; Alam, Md Shamsher] Jazan Univ, Coll Pharm, Dept Pharmaceut Chem, Jazan, Saudi Arabia; Jazan Univ, Coll Pharm, Jazan, Saudi Arabia
推荐引用方式 GB/T 7714	Moni, Sivakumar Sivagurunathan,Sultan, Muhammad H.,Makeen, Hafiz A.,et al. Bioactive principles in exudate gel from the leaf of Aloe fleurentiniorum, traditionally used as folkloric medicine by local people of Aridah and Fayfa mountains, Saudi Arabia[J],2021,14(11).
APA	Moni, Sivakumar Sivagurunathan.,Sultan, Muhammad H..,Makeen, Hafiz A..,Madkhali, Osama A..,Bakkari, Mohammed Ali.,...&Sharahily, Ahmed Mutib.(2021).Bioactive principles in exudate gel from the leaf of Aloe fleurentiniorum, traditionally used as folkloric medicine by local people of Aridah and Fayfa mountains, Saudi Arabia.ARABIAN JOURNAL OF CHEMISTRY,14(11).
MLA	Moni, Sivakumar Sivagurunathan,et al."Bioactive principles in exudate gel from the leaf of Aloe fleurentiniorum, traditionally used as folkloric medicine by local people of Aridah and Fayfa mountains, Saudi Arabia".ARABIAN JOURNAL OF CHEMISTRY 14.11(2021).