干旱区生态环境知识资源中心(Arid): Lipid composition of the stratum corneum in different regions of the body of Kuhl's pipistrelle from the Negev Desert, Israel

Arid

DOI	10.1016/j.cbpa.2021.111074
	Lipid composition of the stratum corneum in different regions of the body of Kuhl's pipistrelle from the Negev Desert, Israel
	Cockley, Alexis; Champagne, Alex M.; Ben-Hamo, Miriam; Pinshow, Berry; Korine, Carmi; Munoz-Garcia, Agusti
通讯作者	Munoz-Garcia, A (corresponding author), Ohio State Univ, Dept Evolut Ecol & Organismal Biol, 1760 Univ Dr, Mansfield, OH 44906 USA.
来源期刊	COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY A-MOLECULAR & INTEGRATIVE PHYSIOLOGY
ISSN	1095-6433
EISSN	1531-4332
出版年	2021
卷号	262
英文摘要	The most superficial epidermal layer in endotherms is the stratum corneum (SC), which is composed of dead corneocytes embedded in a lipid matrix with free fatty acids, cholesterol, ceramides, and cerebrosides; the lipid composition of the SC determines its permeability to water vapor. Lipids that are more polar, have longer hydrocarbon chains, and are less bulky are often packed in more ordered phase states to slow cutaneous evaporative water loss (CEWL); these lipids also resist transitions to more disordered phases at high ambient temperatures (T-a). In bats, wing and tail membranes (wing patagia and tail uropatagium, respectively) allow powered flight, but increase surface area, and hence CEWL, with implications for survival in arid environments. We captured Pipistrellus kuhlii from an arid habitat and measured the lipid composition of the SC of the plagiopatagium in the wing, the uropatagium, and the non-membranous region (NMR) of the body using thin layer chromatography and reversed phase high performance liquid chromatography coupled with atmospheric pressure photoionization mass spectrometry. The patagia contained more cholesterol and shorter-chained ceramides, and fewer cerebrosides than the NMR, indicating that the lipid phase transition temperature in the patagia is lower than in the NMR. Thus, at moderate T-a the lipids in the SC in all body regions will remain in an ordered phase state, allowing water conservation; but as T-a increases, the lipids in the SC of the patagia will more easily transition into a disordered phase, resulting in increased CEWL from the patagia facilitating efficient heat dissipation in hot environments.
英文关键词	Stratum corneum Epidermal lipids Kuhl's pipistrelle P. kuhlii Desert bats
类型	Article
语种	英语
收录类别	SCI-E
WOS记录号	WOS:000717617000007
WOS关键词	CUTANEOUS WATER-LOSS ; PERFORMANCE LIQUID-CHROMATOGRAPHY ; SKIN BARRIER ; PASSER-DOMESTICUS ; PHASE-BEHAVIOR ; HOUSE SPARROWS ; FATTY-ACIDS ; ORGANIZATION ; BATS ; TEMPERATURE
WOS类目	Biochemistry & Molecular Biology ; Physiology ; Zoology
WOS研究方向	Biochemistry & Molecular Biology ; Physiology ; Zoology
来源机构	Ben-Gurion University of the Negev
资源类型	期刊论文
条目标识符	http://119.78.100.177/qdio/handle/2XILL650/368118
作者单位	[Cockley, Alexis; Munoz-Garcia, Agusti] Ohio State Univ, Dept Evolut Ecol & Organismal Biol, 1760 Univ Dr, Mansfield, OH 44906 USA; [Champagne, Alex M.] Univ Southern Indiana, Dept Biol, 8600 Univ Blvd, Evansville, IN 47712 USA; [Ben-Hamo, Miriam] Tel Aviv Univ, Sackler Fac Med, IL-6997801 Tel Aviv, Israel; [Pinshow, Berry; Korine, Carmi] Ben Gurion Univ Negev, Swiss Inst Dryland Environm & Energy Res, Jacob Blaustein Inst Desert Res, Mitrani Dept Desert Ecol, IL-8499000 Midreshet Ben Gurion, Israel
推荐引用方式 GB/T 7714	Cockley, Alexis,Champagne, Alex M.,Ben-Hamo, Miriam,et al. Lipid composition of the stratum corneum in different regions of the body of Kuhl's pipistrelle from the Negev Desert, Israel[J]. Ben-Gurion University of the Negev,2021,262.
APA	Cockley, Alexis,Champagne, Alex M.,Ben-Hamo, Miriam,Pinshow, Berry,Korine, Carmi,&Munoz-Garcia, Agusti.(2021).Lipid composition of the stratum corneum in different regions of the body of Kuhl's pipistrelle from the Negev Desert, Israel.COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY A-MOLECULAR & INTEGRATIVE PHYSIOLOGY,262.
MLA	Cockley, Alexis,et al."Lipid composition of the stratum corneum in different regions of the body of Kuhl's pipistrelle from the Negev Desert, Israel".COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY A-MOLECULAR & INTEGRATIVE PHYSIOLOGY 262(2021).