干旱区生态环境知识资源中心(Arid): Effect of monensin on milk fatty acid profile in dairy cows and on the use of fatty acids for early diagnosis of elevated blood plasma concentrations of nonesterified fatty acids and hyperketonemia

Arid

DOI	10.3168/jds.2020-20041
	Effect of monensin on milk fatty acid profile in dairy cows and on the use of fatty acids for early diagnosis of elevated blood plasma concentrations of nonesterified fatty acids and hyperketonemia
	Henno, M.; Ling, K.; Kaart, T.; Ariko, T.; Karis, P.; Jaakson, H.; Kuusik, S.; Ots, M.
通讯作者	Henno, M (corresponding author), Estonian Univ Life Sci, Inst Vet Med & Anim Sci, Anim Nutr, Kreutzwaldi St 46, EE-51006 Tartu, Estonia.
来源期刊	JOURNAL OF DAIRY SCIENCE
ISSN	0022-0302
EISSN	1525-3198
出版年	2021
卷号	104 期号:9 页码:10355-10362
英文摘要	This work examined the effects of precalving administration of continuous-release monensin capsule on post-calving milk fatty acid (FA) profile and on the accuracy of FA as a biomarker in the early identification of cows with elevated blood plasma nonesterified fatty acids (NEFA) and beta-hydroxybutyrate (BHB) concentrations. Approximately 3 wk before expected calving, 203 multiparous Estonian Holstein cows were randomly divided into control (CO; n = 116) and experimental (MO; n = 87) groups, and a continuous-release capsule of monensin was administered to the MO cows. Blood samples were taken daily in the first 4 d postpartum, then on the sixth or seventh clay in milk, twice in the second week, and thenceforth once per week until the end of the sixth week. Milk samples were taken once from 4 to 7 d in milk, twice in the second week, and thenceforth once per week. Blood samples were analyzed for NEFA and BHB, and milk was analyzed for FA concentrations. Cows with postpartum BHB concentrations >= 1.2 mmol/L at least once during the 6 wk were classified as hyperketonemic (HYK), and cows with NEFA conceritrations >= 1.0 mmol/L as having elevated concentration of NEFA (NEFA(H)). The ability of FA to predict NEFA(H) and HYK cows was studied with logistic regression and receiver operating characteristic curve analysis and the identification accuracy was estimated by area under the receiver operating characteristic curve. For these analyses, we used FA measured on the ninth day after calving. Monensin administration affected FA mobilization and metabolism of the animals as blood NEFA were lower in the MO group on wk 1 and wk 3, and BHB values were considerably lower from wk 1 to wk 4 compared with the CO group. The FA dynamics were generally similar for MO and CO groups. Monensin ad ministration resulted in higher concentrations of C15:0, C16:0, iso C17:0, anteiso C15:0, anteiso C17:0, total trans monounsaturated FA, and C18:2 cis-9,trans-1.1., and lower proportions of C18:0, C18:1 cis-9, arid most of the iso FA. The identification accuracy of NEFA(H) and HYK cows was higher in the CO compared with the MO group and for the identification of HYK compared with NEFA(H) cows (0.75-0.77 vs. 0.78-0.80 in the CO group, and 0.61-0.66 vs. 0.68-0.75 in the MO group for NEFA(H) vs. HYK, respectively). For all FA, the threshold values to identify NEFA(H) and HYK cows were different in the CO and MO groups. Results suggest that specific threshold values for the identification of NEFA(H) and HYK cows could be applicable only within similar feeding conditions and rumen environment.
英文关键词	biomarker milk fatty acid negative energy balance monensin
类型	Article
语种	英语
收录类别	SCI-E
WOS记录号	WOS:000687978800013
WOS关键词	POSSIBLE BIOMARKERS ; ESSENTIAL OILS ; PERFORMANCE ; CATTLE ; METAANALYSIS ; METABOLISM ; STARCH ; IMPACT ; BLEND ; CHAIN
WOS类目	Agriculture, Dairy & Animal Science ; Food Science & Technology
WOS研究方向	Agriculture ; Food Science & Technology
资源类型	期刊论文
条目标识符	http://119.78.100.177/qdio/handle/2XILL650/368093
作者单位	[Henno, M.; Ling, K.; Ariko, T.; Karis, P.; Jaakson, H.; Kuusik, S.; Ots, M.] Estonian Univ Life Sci, Inst Vet Med & Anim Sci, Anim Nutr, Kreutzwaldi St 46, EE-51006 Tartu, Estonia; [Kaart, T.] Estonian Univ Life Sci, Inst Vet Med & Anim Sci, Anim Breeding & Biotechnol, Kreutzwaldi St 62, EE-51006 Tartu, Estonia
推荐引用方式 GB/T 7714	Henno, M.,Ling, K.,Kaart, T.,et al. Effect of monensin on milk fatty acid profile in dairy cows and on the use of fatty acids for early diagnosis of elevated blood plasma concentrations of nonesterified fatty acids and hyperketonemia[J],2021,104(9):10355-10362.
APA	Henno, M..,Ling, K..,Kaart, T..,Ariko, T..,Karis, P..,...&Ots, M..(2021).Effect of monensin on milk fatty acid profile in dairy cows and on the use of fatty acids for early diagnosis of elevated blood plasma concentrations of nonesterified fatty acids and hyperketonemia.JOURNAL OF DAIRY SCIENCE,104(9),10355-10362.
MLA	Henno, M.,et al."Effect of monensin on milk fatty acid profile in dairy cows and on the use of fatty acids for early diagnosis of elevated blood plasma concentrations of nonesterified fatty acids and hyperketonemia".JOURNAL OF DAIRY SCIENCE 104.9(2021):10355-10362.