干旱区生态环境知识资源中心(Arid): Early circulation of rabbit haemorrhagic disease virus type 2 in domestic and wild lagomorphs in southern California, USA (2020-2021)

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DOI	10.1111/tbed.14315
	Early circulation of rabbit haemorrhagic disease virus type 2 in domestic and wild lagomorphs in southern California, USA (2020-2021)
	Asin, Javier; Rejmanek, Daniel; Clifford, Deana L.; Mikolon, Andrea B.; Henderson, Eileen E.; Nyaoke, Akinyi C.; Macias-Rioseco, Melissa; Streitenberger, Nicolas; Beingesser, Juliann; Woods, Leslie W.; Lavazza, Antonio; Capucci, Lorenzo; Crossley, Beate; Uzal, Francisco A.
通讯作者	Asin, J (corresponding author), Univ Calif Davis, Calif Anim Hlth & Food Safety Lab Syst, San Bernardino Branch, San Bernardino, CA 92408 USA.
来源期刊	TRANSBOUNDARY AND EMERGING DISEASES
ISSN	1865-1674
EISSN	1865-1682
出版年	2021-09
英文摘要	Rabbit haemorrhagic disease virus type 2 (RHDV2) causes a severe systemic disease with hepatic necrosis. Differently from classic RHDV, which affects only European rabbits (Oryctolagus cuniculus), RHDV2 can affect many leporid species, including hares (Lepus spp.) and cottontail rabbits (Sylvilagus spp.). RHDV2 emerged in Europe in 2010 and spread worldwide. During the last 5 years, there have been multiple outbreaks in North America since the first known event in 2016 in Quebec, Canada, including several detections in British Columbia, Canada, between 2018 and 2019, Washington State and Ohio, USA, in 2018 and 2019, and New York, USA, in 2020. However, the most widespread outbreak commenced in March 2020 in the southwestern USA and Mexico. In California, RHDV2 spread widely across several southern counties between 2020 and 2021, and the aim of this study was to report and characterize these early events of viral incursion and circulation within the state. Domestic and wild lagomorphs (n = 81) collected between August 2020 and February 2021 in California with a suspicion of RHDV2 infection were tested by reverse transcription quantitative real-time PCR on the liver, and histology and immunohistochemistry for pan-lagovirus were performed on liver sections. In addition, whole genome sequencing from 12 cases was performed. During this period, 33/81 lagomorphs including 24/59 domestic rabbits (O. cuniculus), 3/16 desert cottontail rabbits (Sylvilagus audubonii), and 6/6 black-tailed jackrabbits (Lepus californicus) tested positive. All RHDV2-positive animals had hepatic necrosis typical of pathogenic lagovirus infection, and the antigen was detected in sections from individuals of the three species. The 12 California sequences were closely related (98.9%-99.95%) to each other, and also very similar (99.0%-99.4%) to sequences obtained in other southwestern states during the 2020-2021 outbreak; however, they were less similar to strains obtained in New York in 2020 (96.7%-96.9%) and Quebec in 2016 (92.4%-92.6%), suggesting that those events could be related to different viral incursions. The California sequences were more similar (98.6%-98.7%) to a strain collected in British Columbia in 2018, which suggests that that event could have been related to the 2020 outbreak in the southwestern USA.
英文关键词	California lagomorphs rabbit RHD RHDV2
类型	Article ; Early Access
语种	英语
收录类别	SCI-E
WOS记录号	WOS:000696392000001
WOS关键词	NORTH-AMERICA ; VARIANT ; IDENTIFICATION ; GI.2/RHDV2/B ; OUTBREAK ; RHDV
WOS类目	Infectious Diseases ; Veterinary Sciences
WOS研究方向	Infectious Diseases ; Veterinary Sciences
来源机构	University of California, Davis
资源类型	期刊论文
条目标识符	http://119.78.100.177/qdio/handle/2XILL650/364799
作者单位	[Asin, Javier; Henderson, Eileen E.; Nyaoke, Akinyi C.; Streitenberger, Nicolas; Beingesser, Juliann; Uzal, Francisco A.] Univ Calif Davis, Calif Anim Hlth & Food Safety Lab Syst, San Bernardino Branch, San Bernardino, CA 92408 USA; [Rejmanek, Daniel; Woods, Leslie W.; Crossley, Beate] Univ Calif Davis, Davis Branch, Calif Anim Hlth & Food Safety Lab Syst, Davis, CA 95616 USA; [Clifford, Deana L.] Calif Dept Fish & Wildlife, Wildlife Hlth Lab, Rancho Cordova, CA USA; [Mikolon, Andrea B.] Calif Dept Food & Agr, Sacramento, CA 95814 USA; [Macias-Rioseco, Melissa] Univ Calif Davis, Tulare Branch, Calif Anim Hlth & Food Safety Lab Syst, Tulare, CA USA; [Lavazza, Antonio; Capucci, Lorenzo] Ist Zooprofilatt Sperimentale Lombardia & Emilia, Brescia, Italy; [Lavazza, Antonio; Capucci, Lorenzo] OIE Reference Lab Rabbit Hemorrhag Dis, Brescia, Italy
推荐引用方式 GB/T 7714	Asin, Javier,Rejmanek, Daniel,Clifford, Deana L.,et al. Early circulation of rabbit haemorrhagic disease virus type 2 in domestic and wild lagomorphs in southern California, USA (2020-2021)[J]. University of California, Davis,2021.
APA	Asin, Javier.,Rejmanek, Daniel.,Clifford, Deana L..,Mikolon, Andrea B..,Henderson, Eileen E..,...&Uzal, Francisco A..(2021).Early circulation of rabbit haemorrhagic disease virus type 2 in domestic and wild lagomorphs in southern California, USA (2020-2021).TRANSBOUNDARY AND EMERGING DISEASES.
MLA	Asin, Javier,et al."Early circulation of rabbit haemorrhagic disease virus type 2 in domestic and wild lagomorphs in southern California, USA (2020-2021)".TRANSBOUNDARY AND EMERGING DISEASES (2021).