干旱区生态环境知识资源中心(Arid): Flower beverages of native medicinal plants from Argentina (Acacia caven, Geoffroea decorticans and Larrea divaricata) as antioxidant and anti-inflammatory

Arid

DOI	10.1016/j.jep.2021.114490
	Flower beverages of native medicinal plants from Argentina (Acacia caven, Geoffroea decorticans and Larrea divaricata) as antioxidant and anti-inflammatory
	Isla, Maria Ines; Ezquer, Maria Elisa; Leal, Mariana; Moreno, Maria Alejandra; Zampini, Iris Catiana
通讯作者	Isla, MI ; Zampini, IC (corresponding author), Univ Nacl Tucuman, CONICET, Inst Bioprospecc Fisiol & Vegetal INBIOFIV, UNT,Fac Ciencias Nat, RA-1469 San Miguel De Tucuman, Tucuman, Argentina.
来源期刊	JOURNAL OF ETHNOPHARMACOLOGY
ISSN	0378-8741
EISSN	1872-7573
出版年	2021
卷号	281
英文摘要	Ethnopharmacological relevance: Herbal beverages have been used as a natural part of the medicinal and food culture in northwestern Argentina. The flower beverages (infusion or decoction) of Acacia caven, Geoffroea decorticans and Larrea divaricata, three native species from arid and semiarid regions of Argentina are widely used as anti-inflammatory and anti-rheumatic by several local communities. Aim of the study: The aim of this study was to analyze the phytochemical composition of some Argentine flower beverage and to validate its traditional use as an antioxidant and anti-inflammatory agent. Materials and methods: Phenolic profiles from all flower infusions and decoctions were analyzed by both spectrophotometric analysis and HPLC-DAD. ABTS center dot+; the scavenging activity of both hydrogen peroxide and hydroxyl radical was determined and finally, their ability to inhibit pro-inflammatory enzymes, such as xanthine oxidase (XOD), and lipoxygenase (LOX) was also assessed. Results: The flower beverages of all assayed species showed a high level of phenolic compounds with similar chromatographic patterns in both infusions and decoctions of each plant species, the major components of which have been identified. The flower beverages, especially G. decorticans infusion and decoctions, displayed an important antioxidant activity (SC50 values between 18.14 and 47 mu g/mL) through different mechanisms; all of them were able to inhibit the XOD enzyme activity and, consequently, the formation of uric acid and reactive oxygen species, the primary cause of arthritis-related diseases. The most active beverages as XOD inhibitor were G. decorticans flower infusion and decoctions (IC50 values of 20 and 35 mu g/mL, respectively). Pro-inflammatory enzymes, such as LOX, were also inhibited by infusions and decoctions of G. decorticans, L. cuneifolia and A caven flowers, lessening inflammation mediators in all beverages. Conclusions: The present work validates the traditional medicinal use of flower beverages from Argentina as an anti-rheumatic and anti-inflammatory agent as it has been used for hundreds of years in several pathologies associated with oxidative stress.
英文关键词	Traditional knowledge Infusions and decoctions Polyphenolic profile Antioxidant activity XOD inhibition LOX inhibition
类型	Article
语种	英语
收录类别	SCI-E
WOS记录号	WOS:000704860400007
WOS关键词	NORDIHYDROGUAIARETIC ACID NDGA ; VOLATILE CONSTITUENTS ; RICH FRACTION ; POTENTIAL USE ; IN-VITRO ; EXTRACTS ; DECOCTION ; FLOUR ; INFLAMMATION ; POLYPHENOLS
WOS类目	Plant Sciences ; Chemistry, Medicinal ; Integrative & Complementary Medicine ; Pharmacology & Pharmacy
WOS研究方向	Plant Sciences ; Pharmacology & Pharmacy ; Integrative & Complementary Medicine
资源类型	期刊论文
条目标识符	http://119.78.100.177/qdio/handle/2XILL650/363859
作者单位	Univ Nacl Tucuman, CONICET, Inst Bioprospecc Fisiol & Vegetal INBIOFIV, Lab Invest Produ Nat LIPRON,Fac Ciencias Nat, RA-1469 San Miguel De Tucuman, Tucuman, Argentina; Univ Nacl Tucuman, IML, RA-1469 San Miguel De Tucuman, Tucuman, Argentina
推荐引用方式 GB/T 7714	Isla, Maria Ines,Ezquer, Maria Elisa,Leal, Mariana,et al. Flower beverages of native medicinal plants from Argentina (Acacia caven, Geoffroea decorticans and Larrea divaricata) as antioxidant and anti-inflammatory[J],2021,281.
APA	Isla, Maria Ines,Ezquer, Maria Elisa,Leal, Mariana,Moreno, Maria Alejandra,&Zampini, Iris Catiana.(2021).Flower beverages of native medicinal plants from Argentina (Acacia caven, Geoffroea decorticans and Larrea divaricata) as antioxidant and anti-inflammatory.JOURNAL OF ETHNOPHARMACOLOGY,281.
MLA	Isla, Maria Ines,et al."Flower beverages of native medicinal plants from Argentina (Acacia caven, Geoffroea decorticans and Larrea divaricata) as antioxidant and anti-inflammatory".JOURNAL OF ETHNOPHARMACOLOGY 281(2021).