干旱区生态环境知识资源中心(Arid): Risk Assessment of the Role of the Ecotones in the Transmission of Zoonotic Cutaneous Leishmaniasis in Central Tunisia

Arid

DOI	10.3390/ijerph18179274
	Risk Assessment of the Role of the Ecotones in the Transmission of Zoonotic Cutaneous Leishmaniasis in Central Tunisia
	Barhoumi, Walid; Chelbi, Ifhem; Fares, Wasfi; Zhioua, Sami; Abbas, Mohamed; Derbali, Mohamed; Ramalho-Ortigao, Marcelo; Zhioua, Elyes
通讯作者	Zhioua, E (corresponding author), Pasteur Inst Tunis, Lab Vector Ecol, Tunis 1002, Tunisia. ; Ramalho-Ortigao, M (corresponding author), Uniformed Serv Univ Hlth Sci, Dept Prevent Med & Biostat, Bethesda, MD 20814 USA.
来源期刊	INTERNATIONAL JOURNAL OF ENVIRONMENTAL RESEARCH AND PUBLIC HEALTH
EISSN	1660-4601
出版年	2021
卷号	18 期号:17
英文摘要	Zoonotic cutaneous leishmaniasis (ZCL), endemic in Central and Southern Tunisia, is caused by Leishmania major (Kinetoplastida: Trypanosomatidae), which is transmitted by the sand fly Phlebotomus papatasi. In Tunisia, the fat sand rat Psammomys obesus and the desert jird Meriones shawi are the principal reservoir hosts of L. major. The presence of the P. papatasi vector of the L. major etiologic agent of ZCL was assessed in the vicinity of villages in endemic areas of Central Tunisia. The study was performed from September through October 2019, a period corresponding to the main peak of activity of P. papatasi. Sand flies were collected from rodent burrows located at the ecotone level, which is the transition zone between the natural environment and human settlement. Sand flies were identified to species level and tested for the presence of L. major by PCR. Our entomological survey showed that P. papatasi is the most abundant sand fly species associated with rodent burrows, and this abundance is even higher in ecotones primarily occupied by P. obesus in comparison to ecotones occupied by M. shawi. Infections with Leishmania major were detected only in P. papatasi, with an overall minimum infection rate (MIR) of 2.64%. No significant difference was observed between the MIRs in ecotones of P. obesus and of M. shawi. Incidence of ZCL in the studied areas ranged from 200 to 700 cases per 100,000 inhabitants, with a mean incidence of 385.41 per 100,000. Higher ZCL incidence was identified in ecotones of M. shawi compared to ecotones of P. obesus. ZCL cases are positively correlated with the MIRs. Considering the short flight range of P. papatasi, increases in its densities associated with burrows of P. obesus or M. shawi at the ecotone level expand the overlap of infected vectors with communities and subsequently increase ZCL incidence. Therefore, control measures should target P. papatasi populations at the ecotones.
英文关键词	sand flies rodents ecotones transmission dynamics zoonotic cutaneous leishmaniasis
类型	Article
语种	英语
开放获取类型	gold, Green Published
收录类别	SCI-E ; SSCI
WOS记录号	WOS:000694061700001
WOS关键词	PHLEBOTOMUS-PAPATASI SCOPOLI ; MERIONES-SHAWI DUVERNOY ; MOLECULAR CHARACTERIZATION ; RESERVOIR HOST ; SAND FLIES ; 1914 KINETOPLASTIDA ; PSAMMOMYS-OBESUS ; MAJOR INFECTION ; RIBOSOMAL DNA ; 1842 RODENTIA
WOS类目	Environmental Sciences ; Public, Environmental & Occupational Health
WOS研究方向	Environmental Sciences & Ecology ; Public, Environmental & Occupational Health
资源类型	期刊论文
条目标识符	http://119.78.100.177/qdio/handle/2XILL650/363646
作者单位	[Barhoumi, Walid; Chelbi, Ifhem; Fares, Wasfi; Abbas, Mohamed; Derbali, Mohamed; Zhioua, Elyes] Pasteur Inst Tunis, Lab Vector Ecol, Tunis 1002, Tunisia; [Fares, Wasfi] Pasteur Inst Tunis, Lab Clin Virol, Tunis 1002, Tunisia; [Zhioua, Sami] Pasteur Inst Tunis, Lab Bioinformat, Math, Biostat, Tunis 1002, Tunisia; [Ramalho-Ortigao, Marcelo] Uniformed Serv Univ Hlth Sci, Dept Prevent Med & Biostat, Bethesda, MD 20814 USA
推荐引用方式 GB/T 7714	Barhoumi, Walid,Chelbi, Ifhem,Fares, Wasfi,et al. Risk Assessment of the Role of the Ecotones in the Transmission of Zoonotic Cutaneous Leishmaniasis in Central Tunisia[J],2021,18(17).
APA	Barhoumi, Walid.,Chelbi, Ifhem.,Fares, Wasfi.,Zhioua, Sami.,Abbas, Mohamed.,...&Zhioua, Elyes.(2021).Risk Assessment of the Role of the Ecotones in the Transmission of Zoonotic Cutaneous Leishmaniasis in Central Tunisia.INTERNATIONAL JOURNAL OF ENVIRONMENTAL RESEARCH AND PUBLIC HEALTH,18(17).
MLA	Barhoumi, Walid,et al."Risk Assessment of the Role of the Ecotones in the Transmission of Zoonotic Cutaneous Leishmaniasis in Central Tunisia".INTERNATIONAL JOURNAL OF ENVIRONMENTAL RESEARCH AND PUBLIC HEALTH 18.17(2021).