干旱区生态环境知识资源中心(Arid): Comparative analysis of antioxidant and antiproliferative activities of crude and purified flavonoid enriched fractions of pods/seeds of two desert legumes Prosopis cineraria and Cyamopsis tetragonoloba

Arid

DOI	10.1016/j.heliyon.2021.e07304
	Comparative analysis of antioxidant and antiproliferative activities of crude and purified flavonoid enriched fractions of pods/seeds of two desert legumes Prosopis cineraria and Cyamopsis tetragonoloba
	Asati, Vidushi; Srivastava, Abhilasha; Mukherjee, Sudeshna; Sharma, Pankaj Kumar
通讯作者	Asati, V (corresponding author), BITS Pilani, Dept Biol Sci, Pilani Campus, Pilani 333031, Rajasthan, India.
来源期刊	HELIYON
EISSN	2405-8440
出版年	2021
卷号	7 期号:6
英文摘要	Cyamopsis tetragonoloba and Prosopis cineraria are two legumes of the semi-arid region of Indian subcontinent which are unexplored with respect to their medicinal potential. Moreover, there is considerable lack in the comparative analysis of the biological properties of crude and enriched fractions obtained from the pods and seeds. Therefore, this study aims in investigating the effect of purification on the antioxidant and anticancerous activities of the extracts from the two legumes. This is the first study to purify an enriched methanolic fraction using Amberlite XAD7HP column chromatography followed by analysis using Thin Layer Chromatography. This matrix provided an economic and time efficient isolation of flavonoids and isoflavonoids from the seeds and pods of the above mentioned legumes. In addition, antioxidant activity carried out using DPPH assay showed that purification process did not contributed to enhanced antioxidant potential. However, inverse results were obtained during anticancerous activity assay on Huh-7 cell lines.
英文关键词	Hepatocellular carcinoma Nutrition Desert legumes Cyamopsis tetragonoloba Prosopis cineraria
类型	Article
语种	英语
开放获取类型	gold, Green Published
收录类别	SCI-E
WOS记录号	WOS:000674481000027
WOS关键词	PHYTOCHEMICALS ; CELLS
WOS类目	Multidisciplinary Sciences
WOS研究方向	Science & Technology - Other Topics
资源类型	期刊论文
条目标识符	http://119.78.100.177/qdio/handle/2XILL650/363505
作者单位	[Asati, Vidushi; Srivastava, Abhilasha; Mukherjee, Sudeshna; Sharma, Pankaj Kumar] BITS Pilani, Dept Biol Sci, Pilani Campus, Pilani 333031, Rajasthan, India
推荐引用方式 GB/T 7714	Asati, Vidushi,Srivastava, Abhilasha,Mukherjee, Sudeshna,et al. Comparative analysis of antioxidant and antiproliferative activities of crude and purified flavonoid enriched fractions of pods/seeds of two desert legumes Prosopis cineraria and Cyamopsis tetragonoloba[J],2021,7(6).
APA	Asati, Vidushi,Srivastava, Abhilasha,Mukherjee, Sudeshna,&Sharma, Pankaj Kumar.(2021).Comparative analysis of antioxidant and antiproliferative activities of crude and purified flavonoid enriched fractions of pods/seeds of two desert legumes Prosopis cineraria and Cyamopsis tetragonoloba.HELIYON,7(6).
MLA	Asati, Vidushi,et al."Comparative analysis of antioxidant and antiproliferative activities of crude and purified flavonoid enriched fractions of pods/seeds of two desert legumes Prosopis cineraria and Cyamopsis tetragonoloba".HELIYON 7.6(2021).