干旱区生态环境知识资源中心(Arid): Mitochondrial Sequence Variation, Haplotype Diversity, and Relationships Among Dromedary Camel-Types

Arid

DOI	10.3389/fgene.2021.723964
	Mitochondrial Sequence Variation, Haplotype Diversity, and Relationships Among Dromedary Camel-Types
	Alaqeely, Randa; Alhajeri, Bader H.; Almathen, Faisal; Alhaddad, Hasan
通讯作者	Alhaddad, H (corresponding author), Kuwait Univ, Dept Biol Sci, Kuwait, Kuwait.
来源期刊	FRONTIERS IN GENETICS
EISSN	1664-8021
出版年	2021
卷号	12
英文摘要	Dromedary camels are outstanding livestock that developed efficient abilities to tolerate desert conditions. Many dromedary camel-types (i.e., named populations) exist but lack defined specific breed standards, registries, and breeders' governing organizations. The breed status of dromedary camel-types can partly be assessed by exploring mitochondrial DNA (mtDNA) variation. Accordingly, this study aimed to examine the breed status and the inter-population relationships of dromedary camel-types by analyzing sequence variation in the mtDNA control region and in three coding genes [cytochrome b, threonine, and proline tRNA, and part of the displacement loop (D-loop)] (867 bp region). Tail hair samples (n = 119) that represent six camel-types from Kuwait were collected, extracted, sequenced, and compared to other publicly available sequences (n = 853). Within the sequenced mitochondrial region, 48 polymorphic sites were identified that contributed to 82 unique haplotypes across 37 camel-types. Haplotype names and identities were updated to avoid previous discrepancies. When all sequences were combined (n = 972), a nucleotide diversity of 0.0026 and a haplotype diversity of 0.725 was observed across the dromedary-types. Two major haplogroups (A and B) were identified and the B1 haplotype was predominant and found in almost all dromedary-types whereas the A haplotypes were more abundant in African regions. Non-metric multidimensional scaling revealed an increased similarity among Arabian Peninsula Mezayen camel-types, despite their defining coat colors. The relationships among dromedary camel-types can partly be explained by mtDNA. Future work aimed at a deeper understanding of camel-type breed status should focus on a high number of nuclear markers.
英文关键词	camel mtDNA haplogroup polymorphism population
类型	Article
语种	英语
开放获取类型	gold, Green Published
收录类别	SCI-E
WOS记录号	WOS:000697848200001
WOS关键词	GENETIC DIVERSITY ; POPULATION-GENETICS ; DNA ; WILD ; DOMESTICATION ; HYPOPHYSIS ; INFERENCE ; ANCIENT ; MRBAYES ; REVEAL
WOS类目	Genetics & Heredity
WOS研究方向	Genetics & Heredity
资源类型	期刊论文
条目标识符	http://119.78.100.177/qdio/handle/2XILL650/363315
作者单位	[Alaqeely, Randa; Alhajeri, Bader H.; Alhaddad, Hasan] Kuwait Univ, Dept Biol Sci, Kuwait, Kuwait; [Almathen, Faisal] King Faisal Univ, Coll Vet Med, Dept Vet Publ Hlth, Al Hasa, Saudi Arabia; [Almathen, Faisal] King Faisal Univ, Camel Res Ctr, Al Hasa, Saudi Arabia
推荐引用方式 GB/T 7714	Alaqeely, Randa,Alhajeri, Bader H.,Almathen, Faisal,et al. Mitochondrial Sequence Variation, Haplotype Diversity, and Relationships Among Dromedary Camel-Types[J],2021,12.
APA	Alaqeely, Randa,Alhajeri, Bader H.,Almathen, Faisal,&Alhaddad, Hasan.(2021).Mitochondrial Sequence Variation, Haplotype Diversity, and Relationships Among Dromedary Camel-Types.FRONTIERS IN GENETICS,12.
MLA	Alaqeely, Randa,et al."Mitochondrial Sequence Variation, Haplotype Diversity, and Relationships Among Dromedary Camel-Types".FRONTIERS IN GENETICS 12(2021).