干旱区生态环境知识资源中心(Arid): Genome Divergence and Dynamics in the Thin-Tailed Desert Sheep From Sudan

Arid

DOI	10.3389/fgene.2021.659507
	Genome Divergence and Dynamics in the Thin-Tailed Desert Sheep From Sudan
	Abied, Adam; Ahbara, Abulgasim M.; Berihulay, Haile; Xu, Lingyang; Islam, Rabiul; El-Hag, Faisal M.; Rekik, Mourad; Haile, Aynalem; Han, Jian-Lin; Ma, Yuehui; Zhao, Qianjun; Mwacharo, Joram M.
通讯作者	Zhao, Q (corresponding author), Chinese Acad Agr Sci, Inst Anim Sci, Beijing, Peoples R China. ; Mwacharo, JM (corresponding author), Int Ctr Agr Res Dry Areas ICARDA, Small Ruminant Genom, Addis Ababa, Ethiopia. ; Mwacharo, JM (corresponding author), Roslin Inst, Anim & Vet Sci, Scotland Rural Coll, Roslin, Midlothian, Scotland. ; Mwacharo, JM (corresponding author), Roslin Inst, Ctr Trop Livestock Genet & Hlth CTLGH, Roslin, Midlothian, Scotland.
来源期刊	FRONTIERS IN GENETICS
EISSN	1664-8021
出版年	2021
卷号	12
英文摘要	With climate change bound to affect food and feed production, emphasis will shift to resilient and adapted indigenous livestock to sustain animal production. However, indigenous livestock comprise several varieties, strains and ecotypes whose genomes are poorly characterized. Here, we investigated genomic variation in an African thin-tailed Desert Sheep sampled in Sudan, using 600K genotype data generated from 92 individuals representing five ecotypes. We included data from 18 fat-tailed and 45 thin-tailed sheep from China, to investigate shared ancestry and perform comparative genomic analysis. We observed a clear genomic differentiation between the African thin-tailed Desert Sheep and the Chinese thin-tailed and fat-tailed sheep, suggesting a broad genetic structure between the fat-tailed and thin-tailed sheep in general, and that at least two autosomal gene pools comprise the genome profile of the thin-tailed sheep. Further analysis detected two distinct genetic clusters in both the African thin-tailed Desert Sheep and the Chinese thin-tailed sheep, suggesting a fine-scale and complex genome architecture in thin-tailed sheep. Selection signature analysis suggested differences in adaptation, production, reproduction and morphology likely underly the fine-scale genetic structure in the African thin-tailed Desert Sheep. This may need to be considered in designing breeding programs and genome-wide association studies.
英文关键词	adaptation climate change genetic diversity selection signatures SNP genotypes
类型	Article
语种	英语
开放获取类型	Green Published, gold
收录类别	SCI-E
WOS记录号	WOS:000680355000001
WOS关键词	LINKAGE DISEQUILIBRIUM ; NUCLEAR RECEPTOR ; POPULATION ; GENE ; SELECTION ; REVEALS ; CONSERVATION ; HOMOZYGOSITY ; INFORMATION ; ADAPTATIONS
WOS类目	Genetics & Heredity
WOS研究方向	Genetics & Heredity
资源类型	期刊论文
条目标识符	http://119.78.100.177/qdio/handle/2XILL650/363311
作者单位	[Abied, Adam; Berihulay, Haile; Xu, Lingyang; Islam, Rabiul; Ma, Yuehui; Zhao, Qianjun] Chinese Acad Agr Sci, Inst Anim Sci, Beijing, Peoples R China; [Abied, Adam; El-Hag, Faisal M.] Agr Res Corp, Dry Land Res Ctr & Anim Prod, Khartoum, Sudan; [Ahbara, Abulgasim M.; Haile, Aynalem; Mwacharo, Joram M.] Int Ctr Agr Res Dry Areas ICARDA, Small Ruminant Genom, Addis Ababa, Ethiopia; [El-Hag, Faisal M.] Tottori Univ, Arid Land Res Ctr, Tottori, Japan; [Rekik, Mourad] Int Ctr Agr Res Dry Areas ICARDA, Amman, Jordan; [Han, Jian-Lin] Chinese Acad Agr Sci, Inst Anim Sci, CAAS ILRI Joint Lab Livestock & Forage Genet Reso, Beijing, Peoples R China; [Han, Jian-Lin] Int Livestock Res Inst, Livestock Genet Program, Nairobi, Kenya; [Mwacharo, Joram M.] Roslin Inst, Anim & Vet Sci, Scotland Rural Coll, Roslin, Midlothian, Scotland; [Mwacharo, Joram M.] Roslin Inst, Ctr Trop Livestock Genet & Hlth CTLGH, Roslin, Midlothian, Scotland
推荐引用方式 GB/T 7714	Abied, Adam,Ahbara, Abulgasim M.,Berihulay, Haile,et al. Genome Divergence and Dynamics in the Thin-Tailed Desert Sheep From Sudan[J],2021,12.
APA	Abied, Adam.,Ahbara, Abulgasim M..,Berihulay, Haile.,Xu, Lingyang.,Islam, Rabiul.,...&Mwacharo, Joram M..(2021).Genome Divergence and Dynamics in the Thin-Tailed Desert Sheep From Sudan.FRONTIERS IN GENETICS,12.
MLA	Abied, Adam,et al."Genome Divergence and Dynamics in the Thin-Tailed Desert Sheep From Sudan".FRONTIERS IN GENETICS 12(2021).