干旱区生态环境知识资源中心(Arid): Cluster analysis of allergen reagents in atopic dermatitis patients according to the specific IgE results in ALEX2 Allergy Explorer test

Arid

DOI	10.1080/09540105.2021.1978942
	Cluster analysis of allergen reagents in atopic dermatitis patients according to the specific IgE results in ALEX2 Allergy Explorer test
	Celakovska, J.; Cermakova, E.; Vankova, R.; Krejsek, J.; Andrys, C.
通讯作者	Celakovska, J (corresponding author), Charles Univ Prague, Dept Dermatol & Venereol, Fac Hosp, Hradec Kralove 50002, Czech Republic. ; Celakovska, J (corresponding author), Charles Univ Prague, Med Fac, Hradec Kralove 50002, Czech Republic.
来源期刊	FOOD AND AGRICULTURAL IMMUNOLOGY
ISSN	0954-0105
EISSN	1465-3443
出版年	2021
卷号	32 期号:1 页码:625-649
英文摘要	The aim of this study is the Cluster analysis of specific IgE results in ALEX2 Allergy Explorer test in atopic dermatitis (AD) patients. The complete dermatological and allergological examination including the examination of the sensitisation to allergen reagents with ALEX2 Allergy Explorer testing was performed. The cluster analysis (silhouette value) was processed for results of specific IgE and for clinical parameters. Altogether 100 atopic dermatitis patients were examined - 48 men, 52 women, the average age 40.9 years. Although the distribution of specific IgE results corresponds to the division into protein families, the links between specific IgE to allergens reagents in clusters are weak. Our results strongly point towards cross-reactivity for crustacean-allergic patients to desert locust, house cricket and stable flies. Combining the results of specific IgE for the basic allergen reagents together with the results of specific IgE for less common allergens can help in the estimating of allergic reactions.
英文关键词	Cluster analysis silhouette atopic dermatitis molecular components multiplex ALEX2 Allergy Explorer testing protein families biochemical structure
类型	Article
语种	英语
开放获取类型	gold
收录类别	SCI-E
WOS记录号	WOS:000702924600001
WOS关键词	HOUSE-DUST-MITE ; PERIPHERAL-BLOOD EOSINOPHILIA ; CROSS-REACTIVITY ; POLLEN ALLERGEN ; MAJOR ALLERGEN ; BROWN SHRIMP ; SENSITIZATION ; FOOD ; IDENTIFICATION ; CHILDREN
WOS类目	Chemistry, Applied ; Food Science & Technology ; Immunology ; Toxicology
WOS研究方向	Chemistry ; Food Science & Technology ; Immunology ; Toxicology
资源类型	期刊论文
条目标识符	http://119.78.100.177/qdio/handle/2XILL650/363244
作者单位	[Celakovska, J.] Charles Univ Prague, Dept Dermatol & Venereol, Fac Hosp, Hradec Kralove 50002, Czech Republic; [Celakovska, J.; Vankova, R.; Krejsek, J.; Andrys, C.] Charles Univ Prague, Med Fac, Hradec Kralove 50002, Czech Republic; [Cermakova, E.] Charles Univ Prague, Dept Med Biophys, Med Fac, Hradec Kralove, Czech Republic; [Vankova, R.; Krejsek, J.; Andrys, C.] Charles Univ Prague, Dept Clin Immunol & Allergy, Fac Hosp, Hradec Kralove, Czech Republic
推荐引用方式 GB/T 7714	Celakovska, J.,Cermakova, E.,Vankova, R.,et al. Cluster analysis of allergen reagents in atopic dermatitis patients according to the specific IgE results in ALEX2 Allergy Explorer test[J],2021,32(1):625-649.
APA	Celakovska, J.,Cermakova, E.,Vankova, R.,Krejsek, J.,&Andrys, C..(2021).Cluster analysis of allergen reagents in atopic dermatitis patients according to the specific IgE results in ALEX2 Allergy Explorer test.FOOD AND AGRICULTURAL IMMUNOLOGY,32(1),625-649.
MLA	Celakovska, J.,et al."Cluster analysis of allergen reagents in atopic dermatitis patients according to the specific IgE results in ALEX2 Allergy Explorer test".FOOD AND AGRICULTURAL IMMUNOLOGY 32.1(2021):625-649.