干旱区生态环境知识资源中心(Arid): Removing Disturbing Matrix Constituents from Biota Extracts from Total Extraction and Silicone-Based Passive Sampling

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DOI	10.1002/etc.5153
	Removing Disturbing Matrix Constituents from Biota Extracts from Total Extraction and Silicone-Based Passive Sampling
	Muz, Melis; Rojo-Nieto, Elisa; Jahnke, Annika
通讯作者	Muz, M (corresponding author), UFZ Helmholtz Ctr Environm Res, Dept Effect Directed Anal, Leipzig, Germany.
来源期刊	ENVIRONMENTAL TOXICOLOGY AND CHEMISTRY
ISSN	0730-7268
EISSN	1552-8618
出版年	2021
卷号	40 期号:10 页码:2693-2704
英文摘要	Contaminant analysis in biota extracts can be hampered by matrix interferences caused by, for example, co-extracted lipids that compromise the quality of the analytical data and require frequent maintenance of the analytical instruments. In the present study, using gas chromatography coupled to high resolution mass spectrometry (GC-HRMS), we aimed to develop and validate a straightforward, robust, and reproducible cleanup method with acceptable recoveries for diverse compound classes with a wide range of physicochemical properties representative of pollutant screening in biota extracts. We compared Oasis PRiME HLB cartridges, Agilent Captiva EMR-Lipid cartridges, and Freeze-Out with salmon lipids spiked with 113 target chemicals. The EMR-Lipid cartridges provided extracts with low matrix effects at reproducible recoveries of the multi-class target analytes (93 +/- 9% and 95 +/- 7% for low and high lipid amounts, respectively). The EMR-Lipid cartridges were further tested with spiked pork lipids submitted to total extraction or silicone-based passive sampling. Reproducible recoveries were achieved and matrix residuals were largely removed as demonstrated gravimetrically for both types of extracts. Ion suppression of halogenated compounds was not as efficiently removed by the cleanup of total and silicone-based extracts of pork lipids as for the salmon lipids. However, the samples with clean up provided better instrument robustness than those without cleanup. Hence, EMR-Lipid cartridges were shown to be efficient as a cleanup method in multi-class monitoring of biota samples and open up new possibilities as a suitable cleanup method for silicone extracts in biota passive sampling studies using GC-HRMS analysis. Environ Toxicol Chem 2021;00:1-12. (c) 2021 The Authors. Environmental Toxicology and Chemistry published by Wiley Periodicals LLC on behalf of SETAC.
英文关键词	Multi-class hydrophobic organic chemicals Biota analysis GC-HRMS analysis Matrix effects Cleanup Silicone-based passive sampling
类型	Article
语种	英语
开放获取类型	hybrid, Green Published
收录类别	SCI-E
WOS记录号	WOS:000683908600001
WOS关键词	MULTI-RESIDUE ANALYSIS ; POLYCYCLIC AROMATIC-HYDROCARBONS ; POLYBROMINATED DIPHENYL ETHERS ; PRESSURIZED LIQUID EXTRACTION ; TANDEM MASS-SPECTROMETRY ; POLYCHLORINATED-BIPHENYLS ; RAPID-DETERMINATION ; FLAME RETARDANTS ; THROUGH CLEANUP ; FISH-TISSUES
WOS类目	Environmental Sciences ; Toxicology
WOS研究方向	Environmental Sciences & Ecology ; Toxicology
资源类型	期刊论文
条目标识符	http://119.78.100.177/qdio/handle/2XILL650/363191
作者单位	[Muz, Melis] UFZ Helmholtz Ctr Environm Res, Dept Effect Directed Anal, Leipzig, Germany; [Rojo-Nieto, Elisa; Jahnke, Annika] UFZ Helmholtz Ctr Environm Res, Dept Ecol Chem, Leipzig, Germany; [Jahnke, Annika] Rhein Westfal TH Aachen, Inst Environm Res, Aachen, Germany
推荐引用方式 GB/T 7714	Muz, Melis,Rojo-Nieto, Elisa,Jahnke, Annika. Removing Disturbing Matrix Constituents from Biota Extracts from Total Extraction and Silicone-Based Passive Sampling[J],2021,40(10):2693-2704.
APA	Muz, Melis,Rojo-Nieto, Elisa,&Jahnke, Annika.(2021).Removing Disturbing Matrix Constituents from Biota Extracts from Total Extraction and Silicone-Based Passive Sampling.ENVIRONMENTAL TOXICOLOGY AND CHEMISTRY,40(10),2693-2704.
MLA	Muz, Melis,et al."Removing Disturbing Matrix Constituents from Biota Extracts from Total Extraction and Silicone-Based Passive Sampling".ENVIRONMENTAL TOXICOLOGY AND CHEMISTRY 40.10(2021):2693-2704.