干旱区生态环境知识资源中心(Arid): Scorpion Stings and Antivenom Use in Arizona

Arid

DOI	10.1016/j.amjmed.2021.01.025
	Scorpion Stings and Antivenom Use in Arizona
	Klotz, Stephen A.; Yates, Sarah; Smith, Shannon L.; Dudley, Steven, Jr.; Schmidt, Justin O.; Shirazi, F. Mazda
通讯作者	Klotz, SA (corresponding author), Univ Arizona, Dept Med, 1507 N Campbell Ave, Tucson, AZ 85724 USA.
来源期刊	AMERICAN JOURNAL OF MEDICINE
ISSN	0002-9343
EISSN	1555-7162
出版年	2021
卷号	134 期号:8 页码:1034-1038
英文摘要	BACKGROUND: Arizona: rugged desert landscape harbors many venomous animals, including a small nocturnal scorpion, Centruroides sculpturatus, whose venom can cause severe neuromotor disturbance. An effective antivenom is available at selected health care facilities in the state. METHODS: We analyzed 4398 calls of scorpion stings to the Arizona Poison and Drug Information Center (APDIC) in Tucson over a period of 3 years, from January 2017 to December 2019. RESULTS: We followed 1952 (44.4%) of the victims to resolution. We excluded 2253 callers with minimal effects of the sting and 193 victims with possible toxic effects who were lost to follow-up. The most common complaints among callers were pain at the sting site in 88.9% and local numbness in 62.2%. Detailed clinical information was obtained from 593 calls from a health care facility. Neuromotor signs consistent with C. sculpuratus envenomation included nystagmus in 163 (27.5%), hypersalivation in 91 (15.3%), and fasciculations in 88 (14.8%). Antivenom (Anascorp; Rare Disease Therapeutics, Inc., Franklin, Tenn) was administered to 145 patients. Most were children <5 years old (n = 76, or 54.4%); 27 (18.6%) were 5-9 years old and 42 (30.0%) were >= 10 years of age. About half, 79 of 145 (54.5%) victims who received antivenom, met the APDIC recommended use criteria. CONCLUSIONS: Patients treated with antivenom exhibited a rapid resolution of symptoms without immediate or delayed hypersensitivity reactions. We recommend broadened availability of antivenom at sites where it is most needed. (C) 2021 Elsevier Inc. All rights reserved.
英文关键词	Antivenom Bark scorpion Centruroides sculpturatus Fasciculations Hypersalivation Rotary nystagmus Scorpion stings
类型	Article
语种	英语
收录类别	SCI-E
WOS记录号	WOS:000683323700021
WOS类目	Medicine, General & Internal
WOS研究方向	General & Internal Medicine
来源机构	University of Arizona
资源类型	期刊论文
条目标识符	http://119.78.100.177/qdio/handle/2XILL650/362435
作者单位	[Klotz, Stephen A.; Yates, Sarah; Smith, Shannon L.] Univ Arizona, Div Infect Dis, Dept Med, Tucson, AZ 85724 USA; [Schmidt, Justin O.] Univ Arizona, Dept Entomol, Tucson, AZ 85724 USA; [Dudley, Steven, Jr.; Shirazi, F. Mazda] Univ Arizona, Arizona Poison & Drug Informat Ctr, Tucson, AZ 85724 USA
推荐引用方式 GB/T 7714	Klotz, Stephen A.,Yates, Sarah,Smith, Shannon L.,et al. Scorpion Stings and Antivenom Use in Arizona[J]. University of Arizona,2021,134(8):1034-1038.
APA	Klotz, Stephen A.,Yates, Sarah,Smith, Shannon L.,Dudley, Steven, Jr.,Schmidt, Justin O.,&Shirazi, F. Mazda.(2021).Scorpion Stings and Antivenom Use in Arizona.AMERICAN JOURNAL OF MEDICINE,134(8),1034-1038.
MLA	Klotz, Stephen A.,et al."Scorpion Stings and Antivenom Use in Arizona".AMERICAN JOURNAL OF MEDICINE 134.8(2021):1034-1038.