干旱区生态环境知识资源中心(Arid): Deciphering the metagenome-encoded pathway and domain structure for Palmerolide biosynthesis

Arid

项目编号	1R21CA205932-01A1
	Deciphering the metagenome-encoded pathway and domain structure for Palmerolide biosynthesis
	BAKER, BILL J; CHAIN, PATRICK S. G.; MURRAY, ALISON ELIZABETH (contact)
主持机构	DESERT RESEARCH INSTITUTE
开始日期	2018
结束日期	2020
资助经费	325324(USD)
项目类别	Non-SBIR/STTR RPGs
资助机构	US-NIH（美国国立卫生研究院）
语种	英语
国家	美国
英文简介	Project Narrative: The proposed research aims to identify a metagenome-encoded biosynthetic gene cluster from symbionts of the Antarctic ascidian, Synoicum adareanum, that is responsible for biosynthesis a potent new class of anti-melanoma targeted natural products, Palmerolides. Palmerolides have high specificity to melanoma cells and offer a new mechanism of action to fight metastatic melanoma.
英文关键词	Biotechnology Cancer Cancer Genomics Genetics Human Genome
资源类型	项目
条目标识符	http://119.78.100.177/qdio/handle/2XILL650/356147
推荐引用方式 GB/T 7714	BAKER, BILL J,CHAIN, PATRICK S. G.,MURRAY, ALISON ELIZABETH .Deciphering the metagenome-encoded pathway and domain structure for Palmerolide biosynthesis.2018.