干旱区生态环境知识资源中心(Arid): 超高效液相色谱-高分辨质谱法测定水体中青霉素残留

Arid

	超高效液相色谱-高分辨质谱法测定水体中青霉素残留
其他题名	Determination of Penicillin Residues in Water by Ultra High Performance Liquid Chromatography-High Resolution Mass Spectrometry
	黄思静; 汪义杰; 朱斌; 王建国
来源期刊	中国给水排水
ISSN	1000-4602
出版年	2021
卷号	37 期号:2 页码:112-116
中文摘要	采用超高效液相色谱-高分辨质谱法(UPLC-HRMS)同时测定水体中7种青霉素残留。水样经Oasis HLB固相萃取小柱富集和净化后,用反向C18色谱柱分离,以0.1%的甲酸水溶液和乙腈溶液为流动相进行梯度洗脱,采用电喷雾离子源正离子模式进行检测。7种青霉素类化合物在1.0 ~ 20.0 mug/L的线性范围内,相关系数r均大于0.99,检出限为1 ~ 10 ng/L。实际水样加标回收率为91.15% ~ 106.36%,相对标准偏差为2.30% ~ 8.47%,均小于10%。该方法具有简单快速、准确度高等特点,可以实现水体中7种目标青霉素残留的测定。
英文摘要	High performance liquid chromatography-high resolution mass spectrometry(UPLC-HRMS)was used to determine 7 penicillin residues in water simultaneously.The water samples were enriched and purified by Oasis HLB solid phase extraction column and separated by reverse C18 chromatographic column.Then,gradient elution was implemented with 0.1% formic acid aqueous solution and acetonitrile solution as mobile phase.Finally,electrospray ion source positive ion mode was used for detection of penicillin.The correlation coefficient r of 7 penicillin compounds was greater than 0.99 and the detection limit was 1-10 ng/L in the linear range of 1.0-20.0 mug/L.Actual water sample with standard recovery rate was in the range of 91.15%-106.36%,and the relative standard deviations(RSDs)were 2.30%-8.47%,all less than 10%.The method was simple,fast and highly accurate,and could realize the determination of 7 target penicillin residues in water.
中文关键词	青霉素 ; 固相萃取 ; 超高效液相色谱-高分辨质谱
英文关键词	penicillin solid-phase extraction ultra high performance liquid chromatography-high resolution mass spectrometry(UPLC-HRMS)
类型	Article
语种	中文
收录类别	CSCD
WOS类目	Construction & Building Technology
CSCD记录号	CSCD:6890551
资源类型	期刊论文
条目标识符	http://119.78.100.177/qdio/handle/2XILL650/354556
作者单位	黄思静, 华南理工大学分析测试中心, 广州, 广东 510640, 中国. 朱斌, 华南理工大学分析测试中心, 广州, 广东 510640, 中国. 汪义杰, 珠江水利委员会珠江水利科学研究院, 广州, 广东 510611, 中国. 王建国, 珠江水利委员会珠江水利科学研究院, 广州, 广东 510611, 中国.
推荐引用方式 GB/T 7714	黄思静,汪义杰,朱斌,等. 超高效液相色谱-高分辨质谱法测定水体中青霉素残留[J],2021,37(2):112-116.
APA	黄思静,汪义杰,朱斌,&王建国.(2021).超高效液相色谱-高分辨质谱法测定水体中青霉素残留.中国给水排水,37(2),112-116.
MLA	黄思静,et al."超高效液相色谱-高分辨质谱法测定水体中青霉素残留".中国给水排水 37.2(2021):112-116.