干旱区生态环境知识资源中心(Arid): 通过式固相萃取/超高效液相色谱-串联质谱法测定蔬菜中18种农药残留

Arid

	通过式固相萃取/超高效液相色谱-串联质谱法测定蔬菜中18种农药残留
其他题名	Determination of 18 pesticide residues in vegetables by ultra-performance liquid chromatography-tandem mass spectrometry with pass-through solid phase extraction
	朱富强; 高翠; 刚强; 李艳明; 贾志勇; 张国康
来源期刊	环境化学
ISSN	0254-6108
出版年	2021
卷号	40 期号:3 页码:0254-6108
中文摘要	建立了超高效液相色谱-串联质谱(UPLC-MS/MS)快速测定蔬菜中18种农药残留的方法.样品经乙腈提取后,经Oasis PRiME HLB固相萃取柱净化,采用ACQUITY UPLC HSS T3 C_(18)(50 mm*2.1 mm,1.8 mum)色谱柱进行分离,以0.1%甲酸水溶液和乙腈作为流动相进行梯度洗脱.采用电喷雾电离源、正离子模式下以多反应监测(MRM)进行定性和定量分析.结果表明,18种农药在0.550 mug·L~(-1)范围内线性关系良好(r2 >0.995),方法最低检出限为0.41.5 mug·kg~(-1),最低定量限为1.45.0 mug·kg~(-1).在韭菜、芹菜、番茄、白菜基质中,5、10、50 mug·kg~(-1)添加水平下的加标回收率为60.2%126.9%,相对标准偏差(RSD)为0.4%21.6%(n =3).
英文摘要	An ultra-performance liquid chromatography-tandem mass spectrometry (UPLC-MS/MS) method was established for the rapid determination of 18 pesticide residues in vegetables.Samples were extracted with acetonitrile and cleaned up by the Oasis PRiME HLB column.The separation was performed on an ACQUITY UPLC HSS T3 C_(18)(50 mm*2.1 mm,1.8 mum) column with 0.1% formic acid aqueous solution and acetonitrile as mobile phase by gradient elution.The mass spectrometer was operated in multiple monitoring (MRM) mode with positive mode.The 18 pesticides showed great linear relationships in the range of 0.550 mug·L~(-1) with correlation coefficients (r2) greater than 0.995.The limits of detection (LODs) and limits of quantitation (LOQs) were in the ranges of 0.4 1.5 mug·kg~(-1) and 1.45.0 mug·kg~(-1),respectively.The average recoveries of targets varied from 60.2% to 126.9%,in leek,celery,tomato,cabbage,and the relative standard deviations were between 0.4% and 21.6% at the spiked levels of 5,10 and 50 mug·kg~(-1).
中文关键词	超高效液相色谱-串联质谱法 ; 通过式固相萃取 ; 农药残留 ; 蔬菜
英文关键词	ultra-performance liquid chromatography-tandem mass spectrometry pass-through solid phase extraction pesticide residues vegetables
类型	Article
语种	中文
国家	中国
收录类别	CSCD
WOS类目	Chemistry
CSCD记录号	CSCD:6943004
资源类型	期刊论文
条目标识符	http://119.78.100.177/qdio/handle/2XILL650/354332
作者单位	朱富强, 滨州市食品药品检验检测中心, 滨州, 山东 256600, 中国.; 高翠, 滨州市食品药品检验检测中心, 滨州, 山东 256600, 中国.; 刚强, 滨州市食品药品检验检测中心, 滨州, 山东 256600, 中国.; 李艳明, 滨州市食品药品检验检测中心, 滨州, 山东 256600, 中国.; 贾志勇, 滨州市产品质量监督检验所, 滨州, 山东 256600, 中国.; 张国康, 滨州职业学院, 滨州, 山东 256603, 中国.
推荐引用方式 GB/T 7714	朱富强,高翠,刚强,等. 通过式固相萃取/超高效液相色谱-串联质谱法测定蔬菜中18种农药残留[J],2021,40(3):0254-6108.
APA	朱富强,高翠,刚强,李艳明,贾志勇,&张国康.(2021).通过式固相萃取/超高效液相色谱-串联质谱法测定蔬菜中18种农药残留.环境化学,40(3),0254-6108.
MLA	朱富强,et al."通过式固相萃取/超高效液相色谱-串联质谱法测定蔬菜中18种农药残留".环境化学 40.3(2021):0254-6108.