干旱区生态环境知识资源中心(Arid): The Cytotoxic Effect of the Extract of Anchusa strigosa (Him Him) Grown in Jordan Against Different Cancer Cell Lines

Arid

DOI	10.21123/bsj.2021.18.1.0070
	The Cytotoxic Effect of the Extract of Anchusa strigosa (Him Him) Grown in Jordan Against Different Cancer Cell Lines
	Al-Khatib, Arwa; Al-Khateeb, Iqbal; Abu-Dahab, Rana; Al-Rawi, Naseer
通讯作者	Al-Khatib, A (corresponding author), Al Ahliyya Amman Univ, Fac Pharm, Dept Pharmaceut Sci, PDRC, Amman, Jordan.
来源期刊	BAGHDAD SCIENCE JOURNAL
ISSN	2078-8665
EISSN	2411-7986
出版年	2021
卷号	18 期号:1 页码:70-76
英文摘要	Anchusa strigosa - prickly alkanet from Boraginaceae grows in roadsides, and fields of a broad range of habitats from mediterranean woodlands, to steppe vegetation, to true desert. It is commonly known as him him or lisan al thawr. Anchusa can withstand hard weather conditions and hence is widely cultivated. The color of its flowers can range from pure white to deep cobalt blue. Various parts of A. strigosa are used in traditional medicine for treating several diseases or symptoms, such as abdominal pain, bronchitis, cough, and diarrhea. The goal of this study was to examine the cytotoxic effect of the crude extract of A. strigosa roots and leaves and their fractions against various tumor cell lines: adenocarcinoma MCF-7, human breast ductal carcinoma T-47D; human breast carcinoma MDA-MB-231; and colorectal carcinomas Caco-2. In conclusion the antiproliferative effect was assessed by SRB assay where it showed that the phytochemical constituents in the leaf part of the plant (A. strigosa) do have more potential in depressing the proliferation rate of the cell lines than the root part.
英文关键词	Anchusa strigosa Caco-2 MCF-7 MDA-MB 231
类型	Article
语种	英语
开放获取类型	DOAJ Gold
收录类别	ESCI
WOS记录号	WOS:000648758500010
WOS关键词	PYRROLIZIDINE ALKALOIDS ; ANTIOXIDANT ACTIVITY ; MEDICINAL-PLANTS
WOS类目	Multidisciplinary Sciences
WOS研究方向	Science & Technology - Other Topics
资源类型	期刊论文
条目标识符	http://119.78.100.177/qdio/handle/2XILL650/352743
作者单位	[Al-Khatib, Arwa; Al-Khateeb, Iqbal] Al Ahliyya Amman Univ, Fac Pharm, Dept Pharmaceut Sci, PDRC, Amman, Jordan; [Abu-Dahab, Rana] Univ Jordan, Fac Pharm, Amman, Jordan; [Al-Rawi, Naseer] Al Ahliyya Amman Univ, Fac Pharm, Dept Biopharmaceut & Clin Pharm, PDRC, Amman, Jordan
推荐引用方式 GB/T 7714	Al-Khatib, Arwa,Al-Khateeb, Iqbal,Abu-Dahab, Rana,et al. The Cytotoxic Effect of the Extract of Anchusa strigosa (Him Him) Grown in Jordan Against Different Cancer Cell Lines[J],2021,18(1):70-76.
APA	Al-Khatib, Arwa,Al-Khateeb, Iqbal,Abu-Dahab, Rana,&Al-Rawi, Naseer.(2021).The Cytotoxic Effect of the Extract of Anchusa strigosa (Him Him) Grown in Jordan Against Different Cancer Cell Lines.BAGHDAD SCIENCE JOURNAL,18(1),70-76.
MLA	Al-Khatib, Arwa,et al."The Cytotoxic Effect of the Extract of Anchusa strigosa (Him Him) Grown in Jordan Against Different Cancer Cell Lines".BAGHDAD SCIENCE JOURNAL 18.1(2021):70-76.