干旱区生态环境知识资源中心(Arid): Determination of Acetylsalicylic acid and Naproxen in waste and Tap Water of the Municipal Area of the Sukkur City by SPE-LC-MS/MS

Arid

DOI	10.21743/pjaec/2020.12.25
	Determination of Acetylsalicylic acid and Naproxen in waste and Tap Water of the Municipal Area of the Sukkur City by SPE-LC-MS/MS
	Mirbahar, Waheed Ali; Talpur, Mir Munsif Ali; Pirzada, Tajnees; Musharraf, Syed Ghulam
通讯作者	Talpur, MMA (corresponding author), Shah Abdul Latif Univ, Inst Chem, Khairpur, Sindh, Pakistan.
来源期刊	PAKISTAN JOURNAL OF ANALYTICAL & ENVIRONMENTAL CHEMISTRY
ISSN	1996-918X
EISSN	2221-5255
出版年	2020
卷号	21 期号:2 页码:232-246
英文摘要	This study is based on an environmental assessment of acetylsalicylic acid and naproxen in waste and tap water samples of twenty different locations of municipal area of Sukkur city, Sindh, Pakistan. Both drugs belong to the most frequently used Non-Steroidal Anti-Inflammatory Drugs (NSAIDs) group. The specified pharmaceuticals were extracted from the wastewater and tap water samples by Solid Phase Extraction (SPE) method using Waters Oasis hydrophilic lipophilic balance (HLB) cartridges. Liquid Chromatography-Tandem Mass Spectrometry (LC-MS/MS) technique was applied for the detection and quantification of selected drugs. Negative Electron Spray Ionization (ESI) was used along with Multi Reaction Monitoring (MRM) mode. Pharmaceuticals concentration were found 7.38-827 mu g/L and 5.47-328.95 mu g/L in waste and tap water samples, respectively. The results obtained are comparable with the data reported in literature. Human health risk assessment caused by acetylsalicylic acid and naproxen in aquatic media was observed by applying Risk Quotient (RQ) approach. The calculated RQ values are low enough (order of 10(-3) to 10(-5)) to cause a direct risk for consumers, but their presence in water may pose a danger synergistically.
英文关键词	Waste water Tap water Non-steroidal anti-inflammatory drugs (NSAIDs) Solid phase extraction (SPE) Liquid chromatography-mass spectroscopy (LC-MS/MS) Risk assessment
类型	Article
语种	英语
开放获取类型	DOAJ Gold
收录类别	ESCI
WOS记录号	WOS:000604134000008
WOS关键词	TREATMENT PLANTS ; EMERGING POLLUTANTS ; PHARMACEUTICALS ; REMOVAL ; RISK ; RESIDUES ; METABOLITES ; ENVIRONMENT ; FATE
WOS类目	Chemistry, Analytical
WOS研究方向	Chemistry
资源类型	期刊论文
条目标识符	http://119.78.100.177/qdio/handle/2XILL650/352659
作者单位	[Mirbahar, Waheed Ali; Talpur, Mir Munsif Ali; Pirzada, Tajnees] Shah Abdul Latif Univ, Inst Chem, Khairpur, Sindh, Pakistan; [Musharraf, Syed Ghulam] Univ Karachi, Int Ctr Chem & Biol Sci ICCBS, Karachi 75270, Pakistan
推荐引用方式 GB/T 7714	Mirbahar, Waheed Ali,Talpur, Mir Munsif Ali,Pirzada, Tajnees,et al. Determination of Acetylsalicylic acid and Naproxen in waste and Tap Water of the Municipal Area of the Sukkur City by SPE-LC-MS/MS[J],2020,21(2):232-246.
APA	Mirbahar, Waheed Ali,Talpur, Mir Munsif Ali,Pirzada, Tajnees,&Musharraf, Syed Ghulam.(2020).Determination of Acetylsalicylic acid and Naproxen in waste and Tap Water of the Municipal Area of the Sukkur City by SPE-LC-MS/MS.PAKISTAN JOURNAL OF ANALYTICAL & ENVIRONMENTAL CHEMISTRY,21(2),232-246.
MLA	Mirbahar, Waheed Ali,et al."Determination of Acetylsalicylic acid and Naproxen in waste and Tap Water of the Municipal Area of the Sukkur City by SPE-LC-MS/MS".PAKISTAN JOURNAL OF ANALYTICAL & ENVIRONMENTAL CHEMISTRY 21.2(2020):232-246.