干旱区生态环境知识资源中心(Arid): Young Adults with Mild Asthma in a High-Risk Occupation: Incidence and Risk Factors for Exacerbation

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DOI	10.1159/000515752
	Young Adults with Mild Asthma in a High-Risk Occupation: Incidence and Risk Factors for Exacerbation
	Shapiro, Michael; Zubkov, Konstantin; Rosman, Yossi; Landau, Regev
通讯作者	Shapiro, M (corresponding author), Tel Aviv Sourasky Med Ctr, Dept Internal Med T, Tel Aviv, Israel. ; Shapiro, M (corresponding author), Tel Aviv Univ, Sackler Fac Med, Tel Aviv, Israel. ; Shapiro, M (corresponding author), Israel Def Forces Med Corps, Ramat Gan, Israel.
来源期刊	INTERNATIONAL ARCHIVES OF ALLERGY AND IMMUNOLOGY
ISSN	1018-2438
EISSN	1423-0097
出版年	2021-04
英文摘要	Background: The effects of high-risk environment on young adults with mild asthma were never fully tested in practice, as most high-risk occupations do not welcome them. This study examines the effect of combat training on asthma worsening in the Israeli Defense Forces. Methods: Persons with asthma in remission and mild intermittent asthma who underwent combat training between 2014 and 2017 were compared in terms of disease worsening to their counterparts performing clerical duties during a follow-up of 8 months. Among combat trainees, exposure to known triggers for asthma exacerbation and health status on enlistment were assessed as risk factors for asthma exacerbation. Results: Asthma worsening among persons with asthma in remission was twice as common among those who are undergoing training compared to persons performing clerical duties. This difference was smaller among mild intermittent asthmatics. For both asthma severities, rates of asthma exacerbation requiring emergency room treatment were several times higher among the training group. Among individuals undergoing training, mild intermittent asthma was a significant risk factor for asthma worsening compared to asthma in remission (OR 1.99 [1.44-2.75]) while age (OR 0.67 [0.53-0.85]) and immigration to Israel (OR 0.55 [0.31-0.95]) were significant protective factors. Interpretation: Young adults with mild asthma are at significant risk for severe exacerbations when exposed to high-risk environment even among individuals who have long been symptom free. No single risk factor was found to have an independent effect suggesting a synergistic mechanism that is harder to mitigate.
英文关键词	Asthma Young adults High-risk environment
类型	Article ; Early Access
语种	英语
收录类别	SCI-E
WOS记录号	WOS:000645258800001
WOS关键词	ALLERGIC RHINITIS ; AIR-POLLUTION ; DESERT DUST ; ASSOCIATION ; SEVERITY ; SYMPTOMS ; DISEASES ; CHILDREN ; STRESS ; IMPACT
WOS类目	Allergy ; Immunology
WOS研究方向	Allergy ; Immunology
资源类型	期刊论文
条目标识符	http://119.78.100.177/qdio/handle/2XILL650/352235
作者单位	[Shapiro, Michael] Tel Aviv Sourasky Med Ctr, Dept Internal Med T, Tel Aviv, Israel; [Shapiro, Michael; Rosman, Yossi; Landau, Regev] Tel Aviv Univ, Sackler Fac Med, Tel Aviv, Israel; [Shapiro, Michael; Zubkov, Konstantin; Landau, Regev] Israel Def Forces Med Corps, Ramat Gan, Israel; [Rosman, Yossi] Meir Med Ctr, Allergy & Clin Immunol Unit, Kefar Sava, Israel; [Landau, Regev] Chaim Sheba Med Ctr, Internal Med D, Tel Hashomer, Israel
推荐引用方式 GB/T 7714	Shapiro, Michael,Zubkov, Konstantin,Rosman, Yossi,et al. Young Adults with Mild Asthma in a High-Risk Occupation: Incidence and Risk Factors for Exacerbation[J],2021.
APA	Shapiro, Michael,Zubkov, Konstantin,Rosman, Yossi,&Landau, Regev.(2021).Young Adults with Mild Asthma in a High-Risk Occupation: Incidence and Risk Factors for Exacerbation.INTERNATIONAL ARCHIVES OF ALLERGY AND IMMUNOLOGY.
MLA	Shapiro, Michael,et al."Young Adults with Mild Asthma in a High-Risk Occupation: Incidence and Risk Factors for Exacerbation".INTERNATIONAL ARCHIVES OF ALLERGY AND IMMUNOLOGY (2021).