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DOI10.1002/wps.20869
Preventive psychiatry: a blueprint for improving the mental health of young people
Fusar-Poli, Paolol; Correll, Christoph U.; Arango, Celso; Berk, Michael; Patel, Vikram; Ioannidis, John P. A.
通讯作者Fusar-Poli, P (corresponding author), Kings Coll London, Inst Psychiat Psychol & Neurosci, Dept Psychosis Studies, Early Psychosis Intervent & Clin Detect EPIC Lab, London, England. ; Fusar-Poli, P (corresponding author), South London & Maudsley NHS Fdn Trust, OASIS Serv, London, England. ; Fusar-Poli, P (corresponding author), Univ Pavia, Dept Brain & Behav Sci, Pavia, Italy.
来源期刊WORLD PSYCHIATRY
ISSN1723-8617
EISSN2051-5545
出版年2021
卷号20期号:2页码:200-221
英文摘要Preventive approaches have latterly gained traction for improving mental health in young people. In this paper, we first appraise the conceptual foundations of preventive psychiatry, encompassing the public health, Gordon's, US Institute of Medicine, World Health Organization, and good mental health frameworks, and neurodevelopmentally-sensitive clinical staging models. We then review the evidence supporting primary prevention of psychotic, bipolar and common mental disorders and promotion of good mental health as potential transformative strategies to reduce the incidence of these disorders in young people. Within indicated approaches, the clinical high-risk for psychosis paradigm has received the most empirical validation, while clinical high-risk states for bipolar and common mental disorders are increasingly becoming a focus of attention. Selective approaches have mostly targeted familial vulnerability and non-genetic risk exposures. Selective screening and psychological/psychoeducational interventions in vulnerable subgroups may improve anxiety/depressive symptoms, but their efficacy in reducing the incidence of psychotic/bipolar/common mental disorders is unproven. Selective physical exercise may reduce the incidence of anxiety disorders. Universal psychological/psychoeducational interventions may improve anxiety symptoms but not prevent depressive/anxiety disorders, while universal physical exercise may reduce the incidence of anxiety disorders. Universal public health approaches targeting school climate or social determinants (demographic, economic, neighbourhood, environmental, social/cultural) of mental disorders hold the greatest potential for reducing the risk profile of the population as a whole. The approach to promotion of good mental health is currently fragmented. We leverage the knowledge gained from the review to develop a blueprint for future research and practice of preventive psychiatry in young people: integrating universal and targeted frameworks; advancing multivariable, transdiagnostic, multi-endpoint epidemiological knowledge; synergically preventing common and infrequent mental disorders; preventing physical and mental health burden together; implementing stratified/personalized prognosis; establishing evidence-based preventive interventions; developing an ethical framework, improving prevention through education/training; consolidating the cost-effectiveness of preventive psychiatry; and decreasing inequalities. These goals can only be achieved through an urgent individual, societal, and global level response, which promotes a vigorous collaboration across scientific, health care, societal and governmental sectors for implementing preventive psychiatry, as much is at stake for young people with or at risk for emerging mental disorders.
英文关键词Young people prevention mental disorders preventive psychiatry psychosis bipolar disorder anxiety depression evidence-based medicine neurodevelopment children adolescents
类型Article
语种英语
开放获取类型Green Published, Bronze
收录类别SCI-E ; SSCI
WOS记录号WOS:000651412600009
WOS关键词CLINICAL HIGH-RISK ; ULTRA-HIGH RISK ; MAJOR DEPRESSIVE DISORDER ; AGE-OF-ONSET ; ATTENUATED PSYCHOSIS SYNDROME ; HELP-SEEKING ADOLESCENTS ; INDIVIDUALS AT-RISK ; SOUTH-LONDON OASIS ; BIPOLAR DISORDER ; GENERAL-POPULATION
WOS类目Psychiatry
WOS研究方向Psychiatry
来源机构University of London
资源类型期刊论文
条目标识符http://119.78.100.177/qdio/handle/2XILL650/352006
作者单位[Fusar-Poli, Paolol] Kings Coll London, Inst Psychiat Psychol & Neurosci, Dept Psychosis Studies, Early Psychosis Intervent & Clin Detect EPIC Lab, London, England; [Fusar-Poli, Paolol] South London & Maudsley NHS Fdn Trust, OASIS Serv, London, England; [Fusar-Poli, Paolol] Univ Pavia, Dept Brain & Behav Sci, Pavia, Italy; [Correll, Christoph U.] Northwell Hlth, Zucker Hillside Hosp, Dept Psychiat, Glen Oaks, NY USA; [Correll, Christoph U.] Zucker Sch Med Hofstra Northwell, Dept Psychiat & Mol Med, Hempstead, NY USA; [Correll, Christoph U.] Feinstein Inst Med Res, Ctr Psychiat Neurosci, Manhasset, NY USA; [Correll, Christoph U.] Charite Univ Med Berlin, Dept Child & Adolescent Psychiat, Berlin, Germany; [Arango, Celso] Hosp Gen Univ Gregorio Maranon, Inst Psychiat & Mental Hlth, Dept Child & Adolescent Psychiat, Madrid, Spain; [Arango, Celso] Univ Complutense Madrid, Sch Med, Hlth Res Inst IiGSM, Madrid, Spain; [Arango, Celso] Biomed Res Ctr Mental Hlth CIBERSAM, Madrid, Spain; [Berk, Michael] Deakin Univ...
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Fusar-Poli, Paolol,Correll, Christoph U.,Arango, Celso,et al. Preventive psychiatry: a blueprint for improving the mental health of young people[J]. University of London,2021,20(2):200-221.
APA Fusar-Poli, Paolol,Correll, Christoph U.,Arango, Celso,Berk, Michael,Patel, Vikram,&Ioannidis, John P. A..(2021).Preventive psychiatry: a blueprint for improving the mental health of young people.WORLD PSYCHIATRY,20(2),200-221.
MLA Fusar-Poli, Paolol,et al."Preventive psychiatry: a blueprint for improving the mental health of young people".WORLD PSYCHIATRY 20.2(2021):200-221.
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