干旱区生态环境知识资源中心(Arid): In vitro anthelmintic efficacy of Citrullus colocynthis (L.) Schrad on Haemonchus contortus

Arid

DOI	10.24099/vet.arhiv.1024
	In vitro anthelmintic efficacy of Citrullus colocynthis (L.) Schrad on Haemonchus contortus
	Rehman, Tauseef; Iqbal, Khalid J.; Anwer, Azra; Abbas, Rao Z.; Babar, Wasim; Ali, Ahmad; Khan, Muhammad K.; Javid, Arshad; Khan, Noor; Ali, Hafiz M.; Shahzad, Faisal; Zaman, Muhammad A.; Sikandar, Arbab
通讯作者	Abbas, RZ (corresponding author), Univ Agr Faisalabad, Dept Parasitol, Faisalabad, Pakistan.
来源期刊	VETERINARSKI ARHIV
ISSN	0372-5480
EISSN	1331-8055
出版年	2021
卷号	91 期号:3 页码:307-316
英文摘要	Ethno-veterinary medicinal studies associated with traditional uses of the flora of the Cholistan desert have shown that fruits of Citrullus colocynthis are used for the treatment of helminth infections. The present research was designed to evaluate the anthelmintic efficacy of C. colocynthis against H. contortus. The in vitro anthelmintic effects of aqueous-methanol and ethyl acetate fruit extracts of C. colocynthis against H. contortus were determined through egg hatch and adult motility assays. The effect of four serial dilutions of 25 mu g/mL of each extract compared to levamisol (0.55 mg/mL) and oxfendazole (three serial dilutions of 25 mu g/mL) were studied. Both ethyl acetate and aqueous-methanol extracts paralyzed all adult worms 4h and 8h post-exposure at a dose of 25 mg/mL each. In the egg hatch assay, about 83.67% and 80.67% of H. contortus eggs failed to hatch with the same dose (i.e. 25 mg/mL) of ethyl acetate and CAME extracts. respectively. The results of the present study strongly support fruit extracts of C. colocynthis as a promising alternative to synthetic drugs against H. contortus. These findings will lead to further in vivo studies to investigate the bio-availability of the active ingredients of the plant and the minimum non-lethal concentration required for treatment of haemonchosis in livestock. The anthelmintic effects of C. colocynthis might be attributed to the presence of phenolic acids.
英文关键词	anthelmintic efficacy C. colocynthis H. contortus egg hatch assay adult motility assay
类型	Article
语种	英语
开放获取类型	Green Published, gold
收录类别	SCI-E
WOS记录号	WOS:000667159300009
WOS关键词	ESSENTIAL OILS ; GASTROINTESTINAL HELMINTHS ; SMALL RUMINANTS ; PREVALENCE ; SENEGALENSIS ; ASSOCIATION ; RESISTANCE ; NEMATODES ; LIVESTOCK ; EXTRACTS
WOS类目	Veterinary Sciences
WOS研究方向	Veterinary Sciences
资源类型	期刊论文
条目标识符	http://119.78.100.177/qdio/handle/2XILL650/351933
作者单位	[Rehman, Tauseef; Ali, Hafiz M.; Shahzad, Faisal] Islamia Univ Bahawalpur, Univ Coll Vet & Anim Sci, Bahawalpur, Pakistan; [Iqbal, Khalid J.; Anwer, Azra; Ali, Ahmad] Islamia Univ Bahawalpur, Dept Zool, Bahawalpur, Pakistan; [Abbas, Rao Z.; Khan, Muhammad K.] Univ Agr Faisalabad, Dept Parasitol, Faisalabad, Pakistan; [Babar, Wasim] Cholistan Univ Vet & Anim Sci, Bahawalpur, Pakistan; [Javid, Arshad; Khan, Noor] Univ Vet & Anim Sci, Lahore, Pakistan; [Zaman, Muhammad A.] Coll Vet & Anim Sci, Dept Pathobiol, Jhang, Pakistan; [Sikandar, Arbab] Coll Vet & Anim Sci, Dept Anat, Jhang, Pakistan
推荐引用方式 GB/T 7714	Rehman, Tauseef,Iqbal, Khalid J.,Anwer, Azra,et al. In vitro anthelmintic efficacy of Citrullus colocynthis (L.) Schrad on Haemonchus contortus[J],2021,91(3):307-316.
APA	Rehman, Tauseef.,Iqbal, Khalid J..,Anwer, Azra.,Abbas, Rao Z..,Babar, Wasim.,...&Sikandar, Arbab.(2021).In vitro anthelmintic efficacy of Citrullus colocynthis (L.) Schrad on Haemonchus contortus.VETERINARSKI ARHIV,91(3),307-316.
MLA	Rehman, Tauseef,et al."In vitro anthelmintic efficacy of Citrullus colocynthis (L.) Schrad on Haemonchus contortus".VETERINARSKI ARHIV 91.3(2021):307-316.