干旱区生态环境知识资源中心(Arid): A SNP within the PMCH gene as a molecular marker associated with fertility traits in Angus and Brangus beef heifers raised under a desert environment

Arid

DOI	10.1007/s11250-021-02794-0
	A SNP within the PMCH gene as a molecular marker associated with fertility traits in Angus and Brangus beef heifers raised under a desert environment
	Ismael Angulo-Valenzuela, Norberto; Thomas, Milton G.; Riley, David G.; Medrano, Juan F.; Rolando Reyna-Granados, Javier; Martin Aguilar-Trejo, Carlos; Luna-Nevarez, Pablo
通讯作者	Luna-Nevarez, P (corresponding author), Inst Tecnol Sonora, Dept Ciencias Agronom & Veterinarias, Obregon 85000, Sonora, Mexico.
来源期刊	TROPICAL ANIMAL HEALTH AND PRODUCTION
ISSN	0049-4747
EISSN	1573-7438
出版年	2021
卷号	53 期号:3
英文摘要	Components of the GH/IGF1 endocrine axis regulate growth and reproductive traits in cattle. The pro-melanin-concentrating hormone (PMCH) gene located within chromosome 5 belongs to this axis. Objective herein was to evaluate PMCH single-nucleotide polymorphisms (SNPs) as molecular markers associated with age at first calving, calving interval, and age at second calving in Angus and Brangus beef heifers raised in desert conditions. Five SNPs within the PMCH gene were included in the study. Three of these SNPs had minor allele frequency > 10% and only one SNP did not deviate from Hardy-Weinberg equilibrium. A genotype to phenotype association analyses was performed using a mixed-effects model which included phenotype as the response variable, SNP genotype, breed, year of birth and age of dam as fixed terms, and sire as a random effect. Genotypes from the SNP rs135033882 were found to be associated (P < 0.05) with all evaluated fertility traits, and the term breed resulted as a significant source of variation only for age at second calving. The allele A was the favorable allele because it decreased the age at first calving 98.6 days, the calving interval 85.3 days, and the age at second calving 183.1 days, in Angus and Brangus heifers. In conclusion, we proposed a SNP within the PMCH gene as a potential candidate marker associated with reproductive performance in Angus and Brangus beef heifers raised in a desert climate.
英文关键词	Beef cows Endocrine axis Fertility PMCH SNP
类型	Article
语种	英语
收录类别	SCI-E
WOS记录号	WOS:000662740900002
WOS关键词	CARCASS TRAITS ; HORMONE ; CATTLE
WOS类目	Agriculture, Dairy & Animal Science ; Veterinary Sciences
WOS研究方向	Agriculture ; Veterinary Sciences
来源机构	University of California, Davis ; Colorado State University
资源类型	期刊论文
条目标识符	http://119.78.100.177/qdio/handle/2XILL650/351914
作者单位	[Ismael Angulo-Valenzuela, Norberto; Rolando Reyna-Granados, Javier; Martin Aguilar-Trejo, Carlos; Luna-Nevarez, Pablo] Inst Tecnol Sonora, Dept Ciencias Agronom & Veterinarias, Obregon 85000, Sonora, Mexico; [Thomas, Milton G.] Colorado State Univ, Dept Anim Sci, Ft Collins, CO 80523 USA; [Riley, David G.] Texas A&M Univ, Dept Anim Sci, College Stn, TX 77843 USA; [Medrano, Juan F.] Univ Calif Davis, Dept Anim Sci, Davis, CA 95616 USA
推荐引用方式 GB/T 7714	Ismael Angulo-Valenzuela, Norberto,Thomas, Milton G.,Riley, David G.,et al. A SNP within the PMCH gene as a molecular marker associated with fertility traits in Angus and Brangus beef heifers raised under a desert environment[J]. University of California, Davis, Colorado State University,2021,53(3).
APA	Ismael Angulo-Valenzuela, Norberto.,Thomas, Milton G..,Riley, David G..,Medrano, Juan F..,Rolando Reyna-Granados, Javier.,...&Luna-Nevarez, Pablo.(2021).A SNP within the PMCH gene as a molecular marker associated with fertility traits in Angus and Brangus beef heifers raised under a desert environment.TROPICAL ANIMAL HEALTH AND PRODUCTION,53(3).
MLA	Ismael Angulo-Valenzuela, Norberto,et al."A SNP within the PMCH gene as a molecular marker associated with fertility traits in Angus and Brangus beef heifers raised under a desert environment".TROPICAL ANIMAL HEALTH AND PRODUCTION 53.3(2021).