干旱区生态环境知识资源中心(Arid): Volatile Constituents of Cistanche tubulosa and Their Antioxidant and Antimicrobial Potentials

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DOI	10.25135/rnp.220.20.11.1859
	Volatile Constituents of Cistanche tubulosa and Their Antioxidant and Antimicrobial Potentials
	Musa, Arafa; El-Massr, Khaled F.; El-Ghorab, Ahmed H.; Farouk, Amr; Ali, Hazim M.; Abdelgawad, Mohamed A.; Naguib, Ibrahim A.; Mostafa, Ehab M.
通讯作者	Musa, A (corresponding author), Jouf Univ, Coll Pharm, Dept Pharmacognosy, Sakaka 72341, Aljouf, Saudi Arabia. ; Musa, A (corresponding author), Al Azhar Univ, Fac Pharm, Dept Pharmacognosy, Cairo 11371, Egypt.
来源期刊	RECORDS OF NATURAL PRODUCTS
ISSN	1307-6167
出版年	2021
卷号	15 期号:4 页码:301-311
英文摘要	The hydrodistilled volatile constituents of Cistanche tubulosa (commonly known as Desert Ginseng) have been chemically and biologically investigated. Based on the retention times and mass fragmentation of the obtained GC-MS chromatogram, 106 individual components which representing approximate to 99.29 % of the total volatile constituents have been identified. The major compounds (66.57% of the total composition) were identified as hexanal (15.98%), trans-sabinyl acetate (12.22%), allo-aromadendrene (9.30%), nonanoic acid (6.66%), 3Z-hexeny-2- methyl butanoate (6.09%), valeranone (5.25%), (E, E)-alpha-Farnesene (3.18%), beta-pinene (3.06%), linalool isovalerate (3.03%) and alpha-humulene (1.8%). Estimation of the antioxidant activity of EO showed promising effect at 80 mu g/mL concentration, it exerted 62.40, 863.29 and 62.72 % inhibition compared to TBHQ that showed 78.62, 77.56 and 79.23 % inhibition using DPPH, ABTS and beta-carotene/Linoleic acid, respectively. The antioxidant activity was pronounced at 80 mu g/mL than other concentrations. The volatile constituents showed inhibitory activity against gram positive bacteria ranged from 2.23 mg/100 mL (for staphylococcus aureus), and 15.68 mg/100 mL (for Bacillus cereus) compared to ciprofloxacin which showed inhibitory activity 0.185, and 0.182 mg/100 mL, respectively. Moreover, the MIC of volatiles towards gram negative bacteria are ranged from 18.35 (Escherichia coli) to 31.61 mg/100 mL (Klebsiella pneumonia) compared to ciprofloxacin with 0.184 to 0.188 mg/mL respectively. Additionally, the antifungal activity against candida albicans was rather promising (4.36 mg/mL).
英文关键词	Cistanche tubulosa volatile constituents antioxidant antimicrobial Orobanchaceae
类型	Article
语种	英语
开放获取类型	gold
收录类别	SCI-E
WOS记录号	WOS:000641301200008
WOS关键词	ESSENTIAL OIL ; CHEMICAL-COMPOSITION ; INDEXES
WOS类目	Plant Sciences ; Chemistry, Applied ; Chemistry, Medicinal
WOS研究方向	Plant Sciences ; Chemistry ; Pharmacology & Pharmacy
资源类型	期刊论文
条目标识符	http://119.78.100.177/qdio/handle/2XILL650/351473
作者单位	[Musa, Arafa; Mostafa, Ehab M.] Jouf Univ, Coll Pharm, Dept Pharmacognosy, Sakaka 72341, Aljouf, Saudi Arabia; [Musa, Arafa; Mostafa, Ehab M.] Al Azhar Univ, Fac Pharm, Dept Pharmacognosy, Cairo 11371, Egypt; [El-Massr, Khaled F.; El-Ghorab, Ahmed H.; Ali, Hazim M.] Jouf Univ, Coll Sci, Chem Dept, Sakaka 72341, Aljouf, Saudi Arabia; [El-Massr, Khaled F.; El-Ghorab, Ahmed H.; Farouk, Amr] Natl Res Ctr, Flavour & Aroma Dept, Giza, Egypt; [Abdelgawad, Mohamed A.] Jouf Univ, Coll Pharm, Dept Pharmaceut Chem, Sakaka 72341, Aljouf, Saudi Arabia; [Abdelgawad, Mohamed A.] Beni Suef Univ, Fac Pharm, Dept Pharmaceut Organ Chem, Bani Suwayf 62514, Egypt; [Naguib, Ibrahim A.] Taif Univ, Coll Pharm, Dept Pharmaceut Chem, POB 11099, At Taif 21944, Saudi Arabia
推荐引用方式 GB/T 7714	Musa, Arafa,El-Massr, Khaled F.,El-Ghorab, Ahmed H.,et al. Volatile Constituents of Cistanche tubulosa and Their Antioxidant and Antimicrobial Potentials[J],2021,15(4):301-311.
APA	Musa, Arafa.,El-Massr, Khaled F..,El-Ghorab, Ahmed H..,Farouk, Amr.,Ali, Hazim M..,...&Mostafa, Ehab M..(2021).Volatile Constituents of Cistanche tubulosa and Their Antioxidant and Antimicrobial Potentials.RECORDS OF NATURAL PRODUCTS,15(4),301-311.
MLA	Musa, Arafa,et al."Volatile Constituents of Cistanche tubulosa and Their Antioxidant and Antimicrobial Potentials".RECORDS OF NATURAL PRODUCTS 15.4(2021):301-311.