干旱区生态环境知识资源中心(Arid): Mycoplasma agassizii, an opportunistic pathogen of tortoises, shows very little genetic variation across the Mojave and Sonoran Deserts

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DOI	10.1371/journal.pone.0245895
	Mycoplasma agassizii, an opportunistic pathogen of tortoises, shows very little genetic variation across the Mojave and Sonoran Deserts
	Luzuriaga-Neira, Agusto; Sandmeier, Franziska C.; Weitzman, Chava L.; Tracy, C. Richard; Bauschlicher, Shalyn N.; Tillett, Richard L.; Alvarez-Ponce, David
通讯作者	Alvarez-Ponce, D (corresponding author), Univ Nevada, Dept Biol, Reno, NV 89557 USA. ; Sandmeier, FC (corresponding author), Colorado State Univ, Biol Dept, Pueblo, CO 81001 USA.
来源期刊	PLOS ONE
ISSN	1932-6203
出版年	2021
卷号	16 期号:2
英文摘要	Mycoplasma agassizii is a common cause of upper respiratory tract disease in Mojave desert tortoises (Gopherus agassizii). So far, only two strains of this bacterium have been sequenced, and very little is known about its patterns of genetic diversity. Understanding genetic variability of this pathogen is essential to implement conservation programs for their threatened, long-lived hosts. We used next generation sequencing to explore the genomic diversity of 86 cultured samples of M. agassizii collected from mostly healthy Mojave and Sonoran desert tortoises in 2011 and 2012. All samples with enough sequencing coverage exhibited a higher similarity to M. agassizii strain PS6(T) (collected in Las Vegas Valley, Nevada) than to strain 723 (collected in Sanibel Island, Florida). All eight genomes with a sequencing coverage over 2x were subjected to multiple analyses to detect single-nucleotide polymorphisms (SNPs). Strikingly, even though we detected 1373 SNPs between strains PS6(T) and 723, we did not detect any SNP between PS6(T) and our eight samples. Our whole genome analyses reveal that M. agassizii strain PS6(T) may be present across a wide geographic extent in healthy Mojave and Sonoran desert tortoises.
类型	Article
语种	英语
开放获取类型	gold, Green Published
收录类别	SCI-E
WOS记录号	WOS:000616739700026
WOS关键词	UPPER RESPIRATORY-TRACT ; RIBOSOMAL-RNA GENE ; GOPHERUS-AGASSIZII ; DISEASE ; DIVERSITY ; DYNAMICS ; PATTERNS ; CULTURE ; STRAIN ; DETECT
WOS类目	Multidisciplinary Sciences
WOS研究方向	Science & Technology - Other Topics
来源机构	Colorado State University
资源类型	期刊论文
条目标识符	http://119.78.100.177/qdio/handle/2XILL650/351378
作者单位	[Luzuriaga-Neira, Agusto; Tracy, C. Richard; Alvarez-Ponce, David] Univ Nevada, Dept Biol, Reno, NV 89557 USA; [Sandmeier, Franziska C.; Bauschlicher, Shalyn N.] Colorado State Univ, Biol Dept, Pueblo, CO 81001 USA; [Weitzman, Chava L.] Virginia Polytech Inst & State Univ, Dept Biol Sci, Blacksburg, VA USA; [Tillett, Richard L.] Univ Nevada, Nevada Ctr Bioinformat, Reno, NV 89557 USA
推荐引用方式 GB/T 7714	Luzuriaga-Neira, Agusto,Sandmeier, Franziska C.,Weitzman, Chava L.,et al. Mycoplasma agassizii, an opportunistic pathogen of tortoises, shows very little genetic variation across the Mojave and Sonoran Deserts[J]. Colorado State University,2021,16(2).
APA	Luzuriaga-Neira, Agusto.,Sandmeier, Franziska C..,Weitzman, Chava L..,Tracy, C. Richard.,Bauschlicher, Shalyn N..,...&Alvarez-Ponce, David.(2021).Mycoplasma agassizii, an opportunistic pathogen of tortoises, shows very little genetic variation across the Mojave and Sonoran Deserts.PLOS ONE,16(2).
MLA	Luzuriaga-Neira, Agusto,et al."Mycoplasma agassizii, an opportunistic pathogen of tortoises, shows very little genetic variation across the Mojave and Sonoran Deserts".PLOS ONE 16.2(2021).