干旱区生态环境知识资源中心(Arid): Seroprevalence and associated risk factors for vector-borne pathogens in dogs from Egypt

Arid

DOI	10.1186/s13071-021-04670-0
	Seroprevalence and associated risk factors for vector-borne pathogens in dogs from Egypt
	Selim, Abdelfattah; Alanazi, Abdullah D.; Sazmand, Alireza; Otranto, Domenico
通讯作者	Selim, A (corresponding author), Benha Univ, Dept Anim Med Infect Dis, Fac Vet Med, Toukh 13736, Egypt. ; Alanazi, AD (corresponding author), Shaqra Univ, Fac Sci & Humanities, Dept Biol Sci, POB 1040, Ad Dawadimi 11911, Saudi Arabia. ; Sazmand, A (corresponding author), Bu Ali Sina Univ, Dept Pathobiol, Fac Vet Sci, Hamadan 6517658978, Hamadan, Iran. ; Sazmand, A (corresponding author), Shahid Sadoughi Univ Med Sci, Sch Publ Hlth, Zoonot Dis Res Ctr, Yazd 8915173160, Iran.
来源期刊	PARASITES & VECTORS
ISSN	1756-3305
出版年	2021
卷号	14 期号:1
英文摘要	BackgroundDogs play an important role as reservoirs of many zoonotic vector-borne pathogens worldwide, yet reports of canine vector-borne diseases (CVBDs) in Egypt are scarce.MethodsSerum samples were collected from pet dogs (n=500) of the three most common breeds (German Shepherd, Rottweiler and Pit Bull) in five Governates of Cairo (n=230), Giza (n=110), Al-Qalyubia (n=60), Al-Gharbia (n=60) and Kafr El-Sheikh (n=40) with a hot desert climate. The presence of antibodies to Anaplasma spp. (A. phagocytophilum, A. platys), Ehrlichia spp. (E. canis, E. chaffeensis, E. ewingii), Borrelia burgdorferi (s.l.) and Dirofilaria immitis were assessed using IDEXX SNAP((R)) 4Dx((R)) ELISA tests. For each pathogen, risk factors (i.e. geographical area, keeping condition, sex, age, breed, tick infestation, weekly sanitation of dog enclosures and application of ectoparasiticides) were evaluated by logistic regression approach.ResultsIn total, 18.2% (n=91, 95% CI 15.1-21.8) of dogs scored seropositive for at least one pathogen, the most frequent being Ehrlichia spp. (n=56; 11.2%; 95% CI 8.7-14.3) followed by Anaplasma spp. (n=33; 6.6%, 95% CI 4.7-9.1), Borrelia burgdorferi (s.l.) (n=9; 1.8%, 95% CI 0.9-3.4) and D. immitis (n=7; 1.4%, 95% CI 0.9-2.9). In the tested population, 15.4% (95% CI 12.5-18.8) of dogs were exposed to a single pathogen while 2.4 (95% CI 1.4-4.2) and 0.4% (95% CI 0.1-1.4) were simultaneously exposed to two or three pathogens, respectively. Major risk factors associated with VBDs were living outdoors (Anaplasma spp., P=0.0001; Ehrlichia spp., P=0.0001), female sex (Ehrlichia spp., P=0.005), German Shepherd breed (Anaplasma spp., P=0.04; Ehrlichia spp., P=0.03), tick infestation (Anaplasma spp., P=0.0001; Ehrlichia spp., P=0.0001; B. burgdorferi (s.l.), P=0.003; D. immitis, P=0.02), irregular sanitation (Anaplasma spp., P=0.0001; Ehrlichia spp., P=0.0001; B. burgdorferi (s.l.), P=0.002; D. immitis, P=0.01) and not using ectoparasiticides (Anaplasma spp., P=0.0001; Ehrlichia spp., P=0.0001; B. burgdorferi (s.l.), P=0.007).ConclusionTo our knowledge, this is the first large-scale seroepidemiological study of CVBDs in Egypt. Considering that all of the detected pathogens are potentially zoonotic, effective ectoparasite control strategies, regular examination of pet dogs and successful chemoprophylaxis are advocated.
英文关键词	Anaplasma Borrelia Canine vector-borne pathogens Dirofilaria Egypt Ehrlichia One-health Zoonosis
类型	Article
语种	英语
开放获取类型	gold, Green Published
收录类别	SCI-E
WOS记录号	WOS:000632825900002
WOS类目	Parasitology ; Tropical Medicine
WOS研究方向	Parasitology ; Tropical Medicine
资源类型	期刊论文
条目标识符	http://119.78.100.177/qdio/handle/2XILL650/351287
作者单位	[Selim, Abdelfattah] Benha Univ, Dept Anim Med Infect Dis, Fac Vet Med, Toukh 13736, Egypt; [Alanazi, Abdullah D.] Shaqra Univ, Fac Sci & Humanities, Dept Biol Sci, POB 1040, Ad Dawadimi 11911, Saudi Arabia; [Sazmand, Alireza; Otranto, Domenico] Bu Ali Sina Univ, Dept Pathobiol, Fac Vet Sci, Hamadan 6517658978, Hamadan, Iran; [Sazmand, Alireza] Shahid Sadoughi Univ Med Sci, Sch Publ Hlth, Zoonot Dis Res Ctr, Yazd 8915173160, Iran; [Otranto, Domenico] Univ Bari, Dept Vet Med, I-70010 Bari, Italy
推荐引用方式 GB/T 7714	Selim, Abdelfattah,Alanazi, Abdullah D.,Sazmand, Alireza,et al. Seroprevalence and associated risk factors for vector-borne pathogens in dogs from Egypt[J],2021,14(1).
APA	Selim, Abdelfattah,Alanazi, Abdullah D.,Sazmand, Alireza,&Otranto, Domenico.(2021).Seroprevalence and associated risk factors for vector-borne pathogens in dogs from Egypt.PARASITES & VECTORS,14(1).
MLA	Selim, Abdelfattah,et al."Seroprevalence and associated risk factors for vector-borne pathogens in dogs from Egypt".PARASITES & VECTORS 14.1(2021).