干旱区生态环境知识资源中心(Arid): A NEW METHOD FOR THE DETERMINATION OF NAPHATYLAMINES IN WORKPLACE AIR FOR OCCUPATIONAL EXPOSURE ASSESSMENT

Arid

DOI	10.13075/mp.5893.01054
	A NEW METHOD FOR THE DETERMINATION OF NAPHATYLAMINES IN WORKPLACE AIR FOR OCCUPATIONAL EXPOSURE ASSESSMENT
	Jezewska, Anna; Kondej, Dorota; Woznica, Agnieszka
通讯作者	Jezewska, A (corresponding author), Natl Res Inst, Cent Inst Labour Protect, Dept Chem Aerosol & Biol Hazards, Ul Czerniakowska 16, PL-00701 Warsaw, Poland.
来源期刊	MEDYCYNA PRACY
ISSN	0465-5893
EISSN	2353-1339
出版年	2021
卷号	72 期号:2 页码:145-154
英文摘要	Background: Naphthylamine (NA), i.e., 1-naphthylamine (1-NA) and 2-naphthylamine (2-NA) and its salts (2-naphthylamine hydrochloride and 2-naphthylamine acetate) are colorless crystalline solids. They have been used, among others, in the production of paints and dyes. In the European Union, 1-NA is classified as a toxic substance, and 2-NA and its salts as carcinogenic category 1A. The aim of this study was to develop a new method for the determination of NA, which will enable the determination of 1-NA and 2-NA and its salts in the working environment, in the concentration range of 0.3-6 mu g/m(3). Material and Methods: The method consists in passing the test air containing the substances to be determined through a glass fiber filter impregnated with sulphuric acid(VI). After recovery with water and sodium hydroxide solution followed by extraction into a solid on Oasis HLB columns, the solutions in methanol are analyzed using a high-performance liquid chromatograph with a fluorescence detector and Ultra C18 column. Results: The method developed allows determining 1-NA and 2-NA and its salts in the concentration range of 0.3-6 mu g/m(3). The limit of detection for 1-NA is 81 pg/ml and for 2-NA - 80.6 pg/ml Conclusions: The method is characterized by good precision and accuracy; it meets the requirements of European Standard PN-EN 482 and can be used by occupational hygiene laboratories to measure the level of 1-NA and 2-NA and its salts in workplace air to assess workers' exposure to these substances.
英文关键词	determination method workplace air HPLC environmental engineering health sciences naphthylamine
类型	Article
语种	其他
开放获取类型	gold
收录类别	SCI-E
WOS记录号	WOS:000651752700005
WOS类目	Public, Environmental & Occupational Health
WOS研究方向	Public, Environmental & Occupational Health
资源类型	期刊论文
条目标识符	http://119.78.100.177/qdio/handle/2XILL650/351130
作者单位	[Jezewska, Anna; Kondej, Dorota; Woznica, Agnieszka] Natl Res Inst, Cent Inst Labour Protect, Dept Chem Aerosol & Biol Hazards, Ul Czerniakowska 16, PL-00701 Warsaw, Poland
推荐引用方式 GB/T 7714	Jezewska, Anna,Kondej, Dorota,Woznica, Agnieszka. A NEW METHOD FOR THE DETERMINATION OF NAPHATYLAMINES IN WORKPLACE AIR FOR OCCUPATIONAL EXPOSURE ASSESSMENT[J],2021,72(2):145-154.
APA	Jezewska, Anna,Kondej, Dorota,&Woznica, Agnieszka.(2021).A NEW METHOD FOR THE DETERMINATION OF NAPHATYLAMINES IN WORKPLACE AIR FOR OCCUPATIONAL EXPOSURE ASSESSMENT.MEDYCYNA PRACY,72(2),145-154.
MLA	Jezewska, Anna,et al."A NEW METHOD FOR THE DETERMINATION OF NAPHATYLAMINES IN WORKPLACE AIR FOR OCCUPATIONAL EXPOSURE ASSESSMENT".MEDYCYNA PRACY 72.2(2021):145-154.