干旱区生态环境知识资源中心(Arid): Pathology of Lagovirus europaeus GI.2/RHDV2/b (Rabbit Hemorrhagic Disease Virus 2) in Native North American Lagomorphs

Arid

DOI	10.7589/JWD-D-20-00207
	Pathology of Lagovirus europaeus GI.2/RHDV2/b (Rabbit Hemorrhagic Disease Virus 2) in Native North American Lagomorphs
	Lankton, Julia S.; Knowles, Susan; Keller, Saskia; Shearn-Bochsler, Valerie, I; Ip, Hon S.
通讯作者	Lankton, JS (corresponding author), US Geol Survey, Natl Wildlife Hlth Ctr, 6006 Schroeder Rd, Madison, WI 53711 USA.
来源期刊	JOURNAL OF WILDLIFE DISEASES
ISSN	0090-3558
EISSN	1943-3700
出版年	2021
卷号	57 期号:3 页码:694-700
英文摘要	Rabbit hemorrhagic disease, a notifiable foreign animal disease in the US, was reported for the first time in wild native North American lagomorphs in April 2020 in the southwestern US. Affected species included the desert cottontail (Sylvilagus audubonii), mountain cottontail (Sylvilagus nuttallii), black-tailed jackrabbit (Lepus californicus), and antelope jackrabbit (Lepus alleni). Desert cottontails (n=7) and black-tailed jack-rabbits (n=7) collected in April and May 2020 were necropsied at the US Geological Survey National Wildlife Health Center and tested positive for Lagovirus europaeus GI.2, also known as rabbit hemorrhagic disease virus 2 (GI.2/RHDV2/b), by real-time PCR at the US Department of Agriculture's Foreign Animal Disease Diagnostic Laboratory. Cross and microscopic lesions were similar to those reported in European rabbits (Gryctolagus cuniculus) and other hare (Lepus) species with GI.2/RHDV2/b infection; they included epistaxis (12/13; 92%); massive hepatocellular dissociation (14/14; 100%) and necrosis or apoptosis (11/11; 100%); pulmonary congestion (12/12; 100%), edema (12./13; 92%), and hemorrhage (11/12; 92%); and acute renal tubular injury (3/8; 38%). As in previous reports, massive hepatocellular dissociation and necrosis or apoptosis was the most diagnostically distinct finding. As North American Sylvilagus and Lepus species appear to be susceptible to fatal GI.2/RHDV2/b infection, additional work is needed to understand the host range, pathogenicity, and potential population effects of GI.2/RHDV2/b in North America.
英文关键词	Cottontail jackrabbit Lagovirus Lepus spp. pathology rabbit hemorrhagic disease virus 2 Sylvilagus spp.
类型	Article
语种	英语
收录类别	SCI-E
WOS记录号	WOS:000670799900030
WOS关键词	PCR
WOS类目	Veterinary Sciences
WOS研究方向	Veterinary Sciences
来源机构	United States Geological Survey
资源类型	期刊论文
条目标识符	http://119.78.100.177/qdio/handle/2XILL650/351052
作者单位	[Lankton, Julia S.; Knowles, Susan; Keller, Saskia; Shearn-Bochsler, Valerie, I; Ip, Hon S.] US Geol Survey, Natl Wildlife Hlth Ctr, 6006 Schroeder Rd, Madison, WI 53711 USA; [Keller, Saskia] Univ Wisconsin, Sch Vet Med, Dept Pathobiol Sci, 2015 Linden Dr, Madison, WI 53706 USA
推荐引用方式 GB/T 7714	Lankton, Julia S.,Knowles, Susan,Keller, Saskia,et al. Pathology of Lagovirus europaeus GI.2/RHDV2/b (Rabbit Hemorrhagic Disease Virus 2) in Native North American Lagomorphs[J]. United States Geological Survey,2021,57(3):694-700.
APA	Lankton, Julia S.,Knowles, Susan,Keller, Saskia,Shearn-Bochsler, Valerie, I,&Ip, Hon S..(2021).Pathology of Lagovirus europaeus GI.2/RHDV2/b (Rabbit Hemorrhagic Disease Virus 2) in Native North American Lagomorphs.JOURNAL OF WILDLIFE DISEASES,57(3),694-700.
MLA	Lankton, Julia S.,et al."Pathology of Lagovirus europaeus GI.2/RHDV2/b (Rabbit Hemorrhagic Disease Virus 2) in Native North American Lagomorphs".JOURNAL OF WILDLIFE DISEASES 57.3(2021):694-700.