干旱区生态环境知识资源中心(Arid): Gene expression plasticity and desert adaptation in house mice

Arid

DOI	10.1111/evo.14172
	Gene expression plasticity and desert adaptation in house mice
	Bittner, Noelle K. J.; Mack, Katya L.; Nachman, Michael W.
通讯作者	Nachman, MW (corresponding author), Univ Calif Berkeley, Dept Integrat Biol, Berkeley, CA 94720 USA. ; Nachman, MW (corresponding author), Univ Calif Berkeley, Museum Vertebrate Zool, Berkeley, CA 94720 USA.
来源期刊	EVOLUTION
ISSN	0014-3820
EISSN	1558-5646
出版年	2021
卷号	75 期号:6 页码:1477-1491
英文摘要	Understanding how organisms adapt to new environments is a key problem in evolution, yet it remains unclear whether phenotypic plasticity generally facilitates or hinders this process. Here we studied evolved and plastic responses to water-stress in lab-born descendants of wild house mice (Mus musculus domesticus) collected from desert and non-desert environments and measured gene expression and organismal phenotypes under control and water-stressed conditions. After many generations in the lab, desert mice consumed significantly less water than mice from other localities, indicating that this difference has a genetic basis. Under water-stress, desert mice maintained more weight than non-desert mice, and exhibited differences in blood chemistry related to osmoregulatory function. Gene expression in the kidney revealed evolved differences between mice from different environments as well as plastic responses between hydrated and dehydrated mice. Desert mice showed reduced expression plasticity under water-stress compared to non-desert mice. Importantly, non-desert mice under water-stress generally showed shifts toward desert-like expression, consistent with adaptive plasticity. Finally, we identify several co-expression modules linked to phenotypes of interest. These findings provide evidence for local adaptation after a recent invasion and suggest that adaptive plasticity may have facilitated colonization of the desert environment.
英文关键词	Adaptation desert gene expression Mus plasticity
类型	Article
语种	英语
收录类别	SCI-E
WOS记录号	WOS:000610447000001
WOS类目	Ecology ; Evolutionary Biology ; Genetics & Heredity
WOS研究方向	Environmental Sciences & Ecology ; Evolutionary Biology ; Genetics & Heredity
来源机构	University of California, Berkeley
资源类型	期刊论文
条目标识符	http://119.78.100.177/qdio/handle/2XILL650/350203
作者单位	[Bittner, Noelle K. J.; Mack, Katya L.; Nachman, Michael W.] Univ Calif Berkeley, Dept Integrat Biol, Berkeley, CA 94720 USA; [Bittner, Noelle K. J.; Mack, Katya L.; Nachman, Michael W.] Univ Calif Berkeley, Museum Vertebrate Zool, Berkeley, CA 94720 USA; [Mack, Katya L.] Stanford Univ, Dept Biol, Stanford, CA 94305 USA
推荐引用方式 GB/T 7714	Bittner, Noelle K. J.,Mack, Katya L.,Nachman, Michael W.. Gene expression plasticity and desert adaptation in house mice[J]. University of California, Berkeley,2021,75(6):1477-1491.
APA	Bittner, Noelle K. J.,Mack, Katya L.,&Nachman, Michael W..(2021).Gene expression plasticity and desert adaptation in house mice.EVOLUTION,75(6),1477-1491.
MLA	Bittner, Noelle K. J.,et al."Gene expression plasticity and desert adaptation in house mice".EVOLUTION 75.6(2021):1477-1491.