干旱区生态环境知识资源中心(Arid): Validity of Selection Breeding for High Ephedrine-Alkaloid Content in E. sinica under Different Environments in Japan

Arid

DOI	10.1248/bpb.b20-00765
	Validity of Selection Breeding for High Ephedrine-Alkaloid Content in E. sinica under Different Environments in Japan
	Hiyama, Hajime; Ozawa, Aya; Makino, Bunsho; Yoshioka, Yosuke; Ohsawa, Ryo
通讯作者	Hiyama, H (corresponding author), TSUMURA & CO, Bot Raw Mat Prod Dept, 3586 Yoshiwara, Ami, Ibaraki 3001192, Japan. ; Hiyama, H (corresponding author), Univ Tsukuba, Grad Sch Life & Environm Sci, 1-1-1 Tennodai, Tsukuba, Ibaraki 3058572, Japan. ; Ohsawa, R (corresponding author), Univ Tsukuba, Fac Life & Environm Sci, 1-1-1 Tennodai, Tsukuba, Ibaraki 3058572, Japan.
来源期刊	BIOLOGICAL & PHARMACEUTICAL BULLETIN
ISSN	0918-6158
出版年	2021
卷号	44 期号:2 页码:287-291
英文摘要	Dried terrestrial stems of Ephedra sinica are called 'Ephedra herb,' whose pharmacological effects are due mainly to two major ingredients, (-)-ephedrine and (+)-pseudoephedrine (total alkaloids which are defined in Japanese Pharmacopoeia (TA)). Ephedra herb is an important crude drug in Japan. However, E. sinica is widely distributed in arid areas of northeastern China and Mongolia. Recently, E. sinica has started to be cultivated in Japan. This study aimed to assess the validity of selection breeding on TA content of E. sinica in several locations in Japan. In this experiment, we grew approximately 350 seedlings and divided them randomly into seven groups. Nearly fifty plants were cultivated at each of seven locations. In Ibaraki, Vamanashi, and Shizuoka, average TA content of whole samples satisfied the criteria for Ephedra herb defined in Japanese Pharmacopoeia (7.0 mg/g of dry weight (DW)). Plants with high and intermediate TA content at four locations were selected and transplanted to Ibaraki. There were significant differences in TA content between selected plants with high and intermediate TA content before and after transplanting (p <0.05). TA content of high-TA plants was significantly higher than that of control plants cultivated continuously at Iharaki (p < 0.05). These results suggest that the selection on content of ephedrine alkaloids in E. sinica under various locations in Japan is valid, and high- TA E. sinica plants can be selected at various locations.
英文关键词	Ephedra sinica total alkaloids defined in Japanese Pharmacopoeia breeding selection
类型	Article
语种	英语
开放获取类型	gold
收录类别	SCI-E
WOS记录号	WOS:000620796100020
WOS类目	Pharmacology & Pharmacy
WOS研究方向	Pharmacology & Pharmacy
资源类型	期刊论文
条目标识符	http://119.78.100.177/qdio/handle/2XILL650/349697
作者单位	[Hiyama, Hajime] TSUMURA & CO, Bot Raw Mat Prod Dept, 3586 Yoshiwara, Ami, Ibaraki 3001192, Japan; [Hiyama, Hajime] Univ Tsukuba, Grad Sch Life & Environm Sci, 1-1-1 Tennodai, Tsukuba, Ibaraki 3058572, Japan; [Ozawa, Aya; Makino, Bunsho] TSUMURA & CO, Bot Raw Mat Res Labs, 3586 Yoshiwara, Ami, Ibaraki 3001192, Japan; [Yoshioka, Yosuke; Ohsawa, Ryo] Univ Tsukuba, Fac Life & Environm Sci, 1-1-1 Tennodai, Tsukuba, Ibaraki 3058572, Japan
推荐引用方式 GB/T 7714	Hiyama, Hajime,Ozawa, Aya,Makino, Bunsho,et al. Validity of Selection Breeding for High Ephedrine-Alkaloid Content in E. sinica under Different Environments in Japan[J],2021,44(2):287-291.
APA	Hiyama, Hajime,Ozawa, Aya,Makino, Bunsho,Yoshioka, Yosuke,&Ohsawa, Ryo.(2021).Validity of Selection Breeding for High Ephedrine-Alkaloid Content in E. sinica under Different Environments in Japan.BIOLOGICAL & PHARMACEUTICAL BULLETIN,44(2),287-291.
MLA	Hiyama, Hajime,et al."Validity of Selection Breeding for High Ephedrine-Alkaloid Content in E. sinica under Different Environments in Japan".BIOLOGICAL & PHARMACEUTICAL BULLETIN 44.2(2021):287-291.